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Composition

RITUXIMAB-100MG

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Mabtas T 100 mg Injection

Mabtas T 100 mg Injection belongs to a class of medicines called monoclonal antibodies used in the treatment of non-Hodgkin’s disease and chronic lymphocytic leukaemia. This medicine is also used in treating rheumatoid arthritis in combination with methotrexate and granulomatosis in combination with glucocorticoids. It is also used to treat Pemphigus Vulgaris (PV) and mature B-cell acute leukaemia (B-AL).

Mabtas T 100 mg Injection contains Rituximab, which works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. On the other hand, Mabtas T 100 mg Injection works by interfering with the immune system process that causes inflammation in the joint tissues. Thus, it reduces pain and inflammation and prevents joint damage and disease progression over time

Mabtas T 100 mg Injection may cause certain side effects, such as pale skin, painful urination, night sweats, flushing, back pain, nausea, vomiting, diarrhoea, stomach pain, mouth sores, peeling of skin, injection site reactions and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Mabtas T 100 mg Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Mabtas T 100 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Also, inform your doctor if you have liver/kidney disease, hepatitis B virus infection, cardiac disorders, any active infections, or gastrointestinal disorders before receiving this injection. Mabtas T 100 mg Injection may cause bowel obstruction and perforation, reactivation of Hepatitis B infection, Cardiac arrhythmias, tumour lysis syndrome, and angina in some patients. Hence, careful monitoring should be done during the entire treatment. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Mabtas T 100 mg Injection

Treatment of Non-Hodgkin's disease, rheumatoid arthritis, chronic lymphocytic leukaemia, granulomatosis and pemphigus vulgaris

Medicinal Benefits

Mabtas T 100 mg Injection contains Rituximab, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. On the other hand, Mabtas T 100 mg Injection works by interfering with the immune system process that causes inflammation in the joint tissues. Thus, it reduces pain and inflammation and prevents joint damage and disease progression over time.

Side Effects of Mabtas T 100 mg Injection

  • Pale skin
  • Diarrhoea
  • Painful urination
  • Night sweats
  • Flushing
  • Back pain
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Mouth sores
  • Peeling of skin
  • Cough
  • Bruising or bleeding gums
  • Pain at the site of injection

Directions for Use

Mabtas T 100 mg Injection will be administered by a trained healthcare professional. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Mabtas T 100 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, hepatitis B Virus infection, cardiac disorders, any active infections, or gastrointestinal disorders. Mabtas T 100 mg Injection may cause bowel obstruction and perforation, reactivation of Hepatitis B infection, Cardiac arrhythmias, tumour lysis syndrome (tumour cells release their contents into the bloodstream), and angina in some patients. Hence, careful monitoring should be done during the entire treatment. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Therapeutic Class

CHEMOTHERAPY

Drug Interactions

Drug-Drug Interactions: Mabtas T 100 mg Injection may interact with vaccines, antineoplastic drugs (cisplatin), and other medicines.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease, gastrointestinal disorders, and pulmonary disorders before receiving Mabtas T 100 mg Injection.

Drug-Drug Interactions Checker List

  • CISPLATIN
  • TYPHOID VACCINE
  • CHOLERA VACCINE

Diet & Lifestyle Advise

  • After your treatment begins, dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

What if I have taken an overdose of Mabtas T 100 mg Injection

Since Mabtas T 100 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Special Advise

  • A blood test should be performed such as liver function test, renal function test, and pulmonary function test, to check for liver/kidney function and pulmonary function.
  • Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).

Disease/Condition Glossary

Non-Hodgkin’s Disease: Non-Hodgkin’s disease or Non-Hodgkin’s lymphoma is a blood cancer that affects your lymph system. It causes the uncontrollable growth of cancer cells in the lymph nodes. The lymph system is a part of the immune system which protects your body from disease and infections. Symptoms include lymph node swelling, abdominal pain, chest pain, cough, fever, and night sweats.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that causes joint pain and damage. It occurs when the immune system does not work properly. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. Mabtas T 100 mg Injection is used in combination with methotrexate for the treatment of rheumatoid arthritis.

Chronic lymphocytic leukaemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

Pemphigus Vulgaris: It is a condition that causes painful blisters on the skin and the lining of the mouth, nose, throat and genitals.

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Mabtas T 100 mg Injection. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Mabtas T 100 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are a nursing mother, inform your doctor before receiving Mabtas T 100 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Mabtas T 100 mg Injection will be administered in the hospital setting. Hence, avoid driving.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Mabtas T 100 mg Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Mabtas T 100 mg Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Consult your doctor

Mabtas T 100 mg Injection will be given to the children only if needed. If administered, careful monitoring of the child is needed.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - MAB0009

FAQs

Mabtas T 100 mg Injection is used to treat Non-Hodgkin’s disease, rheumatoid arthritis, chronic lymphocytic leukaemia, granulomatosis and pemphigus vulgaris.
Mabtas T 100 mg Injection contains Rituximab, which works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth.
Mabtas T 100 mg Injection may cause bowel obstruction and perforation, reactivation of Hepatitis B infection, Cardiac arrhythmias, tumour lysis syndrome, and angina in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.
Mabtas T 100 mg Injection contains the active substance rituximab. This is a type of protein called a monoclonal antibody.
The common side effects of Mabtas T 100 mg Injection are pale skin, painful urination, night sweats, flushing, back pain, nausea, vomiting, diarrhoea, stomach pain, mouth sores, peeling of skin, injection site reactions and pain at the site of injection. If any of these side effects persist or worsen, please consult your doctor.

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