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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Lynparza 100 mg Tablet is used to treat various cancers, including ovarian, breast, pancreatic, and prostate. It contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage. Avoid taking this medication if you are pregnant or breastfeeding because this can cause harmful effects on the unborn baby. Both women and men using this should use birth control to avoid pregnancy.

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Composition :

OLAPARIB-100MG

Manufacturer/Marketer :

Steris Healthcare

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lynparza 100 mg Tablet

Lynparza 100 mg Tablet is an 'anti-cancer' drug used to treat various cancers, including ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.

Lynparza 100 mg Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

To treat your condition effectually, continue taking Lynparza 100 mg Tablet for as long as your doctor has prescribed. Do not stop using the Lynparza 100 mg Tablet midway. Talk to your doctor before taking Lynparza 100 mg Tablet if you have severe allergic reactions to Lynparza 100 mg Tablet or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Lynparza 100 mg Tablet if you are pregnant or breastfeeding because this Lynparza 100 mg Tablet can cause harmful effects on the unborn baby. Both women and men using this Lynparza 100 mg Tablet should use birth control to avoid pregnancy. While on Lynparza 100 mg Tablet treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.

Uses of Lynparza 100 mg Tablet

Treatment of Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Lynparza 100 mg Tablet belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate.  Lynparza 100 mg Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

How Lynparza 100 mg Tablet Works

Lynparza 100 mg Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lynparza 100 mg Tablet

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Feeling tired or weak (fatigue)
  • Feeling very tired
  • Indigestion or heartburn (dyspepsia)
  • Loss of appetite
  • Headache
  • Changes in the taste of foods (dysgeusia)
  • Feeling dizzy
  • Cough
  • Shortness of breath (dyspnoea)
  • Diarrhoea
  • Low white blood cell count (leukopenia or neutropenia)
  • Rash
  • Sore mouth (stomatitis)
  • Upper abdominal pain (pain in the stomach area under the ribs)
  • Blood clot in a deep vein, usually in the leg (venous thrombosis)

What if I have taken an overdose of Lynparza 100 mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Lynparza 100 mg Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Lynparza 100 mg Tablet for as long as your doctor has prescribed. Do not stop Lynparza 100 mg Tablet midway. Talk to your doctor before taking Lynparza 100 mg Tablet if you have severe allergic reactions to Lynparza 100 mg Tablet or other medicines or suffer from any medical illness. Avoid taking Lynparza 100 mg Tablet if you are pregnant or breastfeeding because this Lynparza 100 mg Tablet can cause harmful effects on the unborn baby. Both women and men using this Lynparza 100 mg Tablet should use birth control to avoid pregnancy. Do not start Lynparza 100 mg Tablet unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Lynparza 100 mg Tablet and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Lynparza 100 mg Tablet.

Drug-Drug Interactions

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OlaparibDiltiazem
Severe
OlaparibArmodafinil
Severe

Drug-Drug Interactions

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OlaparibDiltiazem
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Using Diltiazem and Lynparza 100 mg Tablet 8's can increase the blood levels of Lynparza 100 mg Tablet 8's. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Diltiazem and Lynparza 100 mg Tablet 8's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibArmodafinil
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Taking Armodafinil and Lynparza 100 mg Tablet 8's may reduce the blood levels of Lynparza 100 mg Tablet 8's, which may reduce the effect of Lynparza 100 mg Tablet 8's.

How to manage the interaction:
Although there is a possible interaction between Armodafinil and Lynparza 100 mg Tablet 8's, you can take these medicines together if prescribed by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without consulting a doctor.
OlaparibBaricitinib
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Coadministration of Baricitinib and Lynparza 100 mg Tablet 8's can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Lynparza 100 mg Tablet 8's if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
OlaparibAtazanavir
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Using Atazanavir and Lynparza 100 mg Tablet 8's can increase the blood levels of Lynparza 100 mg Tablet 8's. This can increase the risk and/or severity of side effects Lynparza 100 mg Tablet 8's.

How to manage the interaction:
Combining Atazanavir and Lynparza 100 mg Tablet 8's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
OlaparibFosphenytoin
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
When Lynparza 100 mg Tablet 8's is taken with Fosphenytoin, it can cause Lynparza 100 mg Tablet 8's to be broken down faster in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Co-administration of Lynparza 100 mg Tablet 8's with Fosphenytoin can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
OlaparibKetoconazole
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Using Ketoconazole and Lynparza 100 mg Tablet 8's can increase the blood levels of Lynparza 100 mg Tablet 8's. This can increase the risk and/or severity of side effects (nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells).

How to manage the interaction:
Combining Ketoconazole and Lynparza 100 mg Tablet 8's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
OlaparibDeferiprone
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Combining Deferiprone and Lynparza 100 mg Tablet 8's can increase the risk of lowering white blood cell count and affect white blood cells or bone marrow function.

How to manage the interaction:
Combining Deferiprone and Lynparza 100 mg Tablet 8's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibErythromycin
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Coadministration of Lynparza 100 mg Tablet 8's and erythromycin may significantly increase the blood levels of Lynparza 100 mg Tablet 8's. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, less desire to eat, abdominal pain or discomfort.

How to manage the interaction:
Combining Erythromycin and Lynparza 100 mg Tablet 8's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibEfavirenz
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
When Lynparza 100 mg Tablet 8's is taken with Efavirenz, it can cause Lynparza 100 mg Tablet 8's to be broken down faster in the body.

How to manage the interaction:
Although taking Lynparza 100 mg Tablet 8's and Efavirenz together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
OlaparibLetermovir
Severe
How does the drug interact with Lynparza 100 mg Tablet 8's:
Using Letermovir and Lynparza 100 mg Tablet 8's can increase the blood levels of Lynparza 100 mg Tablet 8's. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Letermovir and Lynparza 100 mg Tablet 8's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Lynparza 100 mg Tablet Substitute

Substitutes safety advice
  • Bracanat 100 Tablet 30's

    188.33per tablet
  • Bdparp 100 Tablet 28's

    593.04per tablet
  • Bdparp 100 Tablet 56's

    593.04per tablet
  • Brcaone 100 Tablet 60's

    492.00per tablet
  • Obrenza 100 Tablet 60's

    257.89per tablet
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Lynparza 100 mg Tablet.

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Pregnancy

Unsafe

Lynparza 100 mg Tablet should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Lynparza 100 mg Tablet and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Unsafe

Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.

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Driving

Caution

Lynparza 100 mg Tablet may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Lynparza 100 mg Tablet in pediatric patients have not been established.

FAQs

Lynparza 100 mg Tablet is used to treat ovarian, breast, pancreatic, and prostate cancers.
Lynparza 100 mg Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.
If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Lynparza 100 mg Tablet.
Yes, Lynparza 100 mg Tablet can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.
Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Country of origin

Germany

Manufacturer/Marketer address

Tanaji Chowk, Mumbai
Other Info - LYN0035

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