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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:47 PM IST
Luprova 22.5 Injection is used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. It contains Leuprolide which works by inhibiting the synthesis of testosterone in men and oestrogen in women. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition :

LEUPROLIDE-22.5MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Luprova 22.5 Injection

Luprova 22.5 Injection belongs to the class of 'anticancer or anti-neoplastic agents', primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Luprova 22.5 Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

Take Luprova 22.5 Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Luprova 22.5 Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

To treat your condition effectually continue taking Luprova 22.5 Injection for as long as your doctor has prescribed. Do not stop Luprova 22.5 Injection midway.  Avoid taking Luprova 22.5 Injection if you are pregnant or breastfeeding because this Luprova 22.5 Injection can cause harmful effects on the unborn baby. Both women and men using this Luprova 22.5 Injection should use birth control to avoid pregnancy. Luprova 22.5 Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Luprova 22.5 Injection is not recommended for children below two years of age. Luprova 22.5 Injection may make you feel dizzy, hence drive when you are alert only.

Uses of Luprova 22.5 Injection

Treatment of Prostate cancer, Breast cancer, Endometriosis, Precocious puberty.

Medicinal Benefits

Luprova 22.5 Injection contains Leuprolide, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Luprova 22.5 Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Luprova 22.5 Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Luprova 22.5 Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis and breast cancer.

Side Effects of Luprova 22.5 Injection

  • Weight changes
  • Hot flushes
  • Muscle weakness
  • Bone Pain
  • Loss of interest in sexual intercourse
  • Inability to have an erection
  • Tiredness
  • Difficulty sleeping
  • Headaches
  • Breast tenderness
  • Changes in breast size
  • Mood swings
  • Abdominal pain
  • Vomiting (feeling sick)
  • Acne
  • Vaginal Bleeding 
  • Spotting
  • Injection site reactions (skin hardening, redness, pain, abscesses, swelling, nodules, ulcers and skin damage)

Directions for Use

Luprova 22.5 Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Luprova 22.5 Injection or any other medicines, please tell your doctor. Luprova 22.5 Injection can affect the unborn baby when used in pregnancy. Hence, Luprova 22.5 Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Luprova 22.5 Injection, make sure to use reliable forms of contraception to prevent pregnancy during the course. Luprova 22.5 Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Use the Luprova 22.5 Injection with caution in elderly patients and children. Luprova 22.5 Injection is not recommended for children younger than two years of age. Your symptoms may become temporarily worse when you first start taking Luprova 22.5 Injection. Inform your doctor if this continues for longer than 2 months. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting Luprova 22.5 Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Luprova 22.5 Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Luprova 22.5 Injection. Luprova 22.5 Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

verifiedApollotooltip
LeuprorelinPimozide
Critical
LeuprorelinVandetanib
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Habit Forming

No

How Luprova 22.5 Injection Works

Luprova 22.5 Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

What if I have taken an overdose of Luprova 22.5 Injection

Since this medication is given by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Luprova 22.5 Injection to avoid unpleasant side-effects. Alcohol intake, along with Luprova 22.5 Injection, may cause increased drowsiness.

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Pregnancy

Unsafe

Luprova 22.5 Injection is a pregnancy category X drug. Luprova 22.5 Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective method of contraception while taking fluorouracil and for at least 6 months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Luprova 22.5 Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Luprova 22.5 Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Luprova 22.5 Injection.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Luprova 22.5 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Luprova 22.5 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Caution

Luprova 22.5 Injection is not recommended in children younger than two years of age.

Country of origin

INDIA

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - LUP0313

Author Details

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FAQs

Luprova 22.5 Injection is used to treat prostate cancer in men, breast cancer & endometriosis in women and precocious puberty (early puberty) in children.
Luprova 22.5 Injection contains Leuprolide, a synthetic hormone that helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis in women.
Yes, Luprova 22.5 Injection commonly affects the hair by making them thin which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen lowering effect of Luprova 22.5 Injection. These effects are not long-lasting and may return after some time. If it matters to you then inform your doctor for further advice.
Luprova 22.5 Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Luprova 22.5 Injection.
Luprova 22.5 Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Luprova 22.5 Injection and inform your doctor if you have diabetes before taking Luprova 22.5 Injection.
Luprova 22.5 Injection may worsen your mood disorders like depression. Hence it is advised to use Luprova 22.5 Injection only when you are free from any kind of mental problems. Please consult your doctor for more information.
Luprova 22.5 Injection is not recommended for patients suffering from heart rhythm problems such as arrhythmia (irregular heartbeat) as it may increase the risk of heart rhythm problems. Therefore, inform your doctor if you have any heart problems before taking Luprova 22.5 Injection.
Luprova 22.5 Injection may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Luprova 22.5 Injection.
Before starting treatment with Luprova 22.5 Injection, you should inform your doctor if you are allergic to any of its ingredients. Let your doctor know if you are pregnant or breastfeeding, as Luprova 22.5 Injection could harm the unborn baby. Luprova 22.5 Injection may also affect fertility in men, so discuss with your doctor if you plan to start a family in the future. Also, make sure to inform your doctor if you have a history of liver or kidney disease, heart disease, recent heart attack, depression, brain tumours, electrolyte imbalances, diabetes, seizures, weak bones, or high cholesterol levels.
No, Luprova 22.5 Injection does not need to be refrigerated. It should be stored at room temperature, away from direct sunlight.
Luprova 22.5 Injection is typically administered by a healthcare provider either under the skin (subcutaneously) or into a muscle (intramuscularly). Please do not self-administer Luprova 22.5 Injection.
No, Luprova 22.5 Injection is not a chemotherapy medicine. Luprova 22.5 Injection is a hormonal medicine that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similarly to the GnRH hormone produced by the hypothalamus in the brain.
Yes, Luprova 22.5 Injection can stop periods. It is used to treat endometriosis, a condition where tissue similar to the lining of the uterus (womb) grows outside the uterus and causes painful or irregular periods. Luprova 22.5 Injection works by suppressing the production of hormones that regulate the menstrual cycle, which can create a temporary menopause-like state, stopping periods for a while.
Yes, Luprova 22.5 Injection is a hormonal medicine that works by suppressing the production of reproductive hormones in females. Using Luprova 22.5 Injection during pregnancy is not recommended, as it may harm the developing foetus (newborn baby). Its use should be avoided during pregnancy unless prescribed by your doctor.
Taking Luprova 22.5 Injection may affect your bone health by lowering certain hormone levels (such as oestrogen or testosterone), which can lead to decreased bone mineral density over time. Please consult your doctor about the potential risks of using Luprova 22.5 Injection and ask about steps you can take to help protect your bones.
Luprova 22.5 Injection may increase blood sugar levels (hyperglycaemia) or make existing diabetes worse. It is important to monitor your blood sugar levels while using Luprova 22.5 Injection and consult your doctor if you have any concerns before or during treatment.

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Keep Refrigerated. Do not freeze.

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