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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Luprocare Depot 3.75 gm Injection is used to treat prostate cancer in men, endometriosis & hormone-responsive breast cancer in women and premature puberty in children. It contains Leuprorelin which works by decreasing the levels of testosterone in men and oestrogen in women. It also inhibits the growth of the tumour or causes it to shrink. In some cases, this medicine may cause side effects such as pain, redness, swelling, or skin hardening at the injection site. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

LEUPRORELIN-100MG

Manufacturer/Marketer :

Daylon healthcare pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Luprocare Depot 3.75 gm Injection

Luprocare Depot 3.75 gm Injection belongs to the class of synthetic hormones used in the treatment of prostate cancer in men, endometriosis, and hormone-responsive breast cancer in women. Also, Luprocare Depot 3.75 gm Injection is used to treat premature puberty in children. Prostate cancer is cancer of the prostate gland (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Luprocare Depot 3.75 gm Injection contains Leuprorelin, a synthetic hormone that works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and estrogen in women. Thereby, Luprocare Depot 3.75 gm Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumor or causing it to shrink.  

Use Luprocare Depot 3.75 gm Injection as prescribed by your doctor. You are advised to take Luprocare Depot 3.75 gm Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience pain, redness, swelling, or skin hardening at the injection site, muscle weakness, bone pain, inability to have an erection, breast tenderness, headache, vaginal dryness, changes in breast size, acne, or mood swings. Most of these side effects of Luprocare Depot 3.75 gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Luprocare Depot 3.75 gm Injection or any other medicines, please tell your doctor. Luprocare Depot 3.75 gm Injection is contraindicated in pregnant and breastfeeding women. It is advised to use effective contraceptive measures to avoid pregnancy while taking Luprocare Depot 3.75 gm Injection as it may cause birth defects. Luprocare Depot 3.75 gm Injection should be used with caution in children. You are recommended to avoid or limit consumption of alcohol with Luprocare Depot 3.75 gm Injection as it may increase the risk of bone density loss. Drive only if you are alert as Luprocare Depot 3.75 gm Injection may cause dizziness, drowsiness, or vision disturbances.

Uses of Luprocare Depot 3.75 gm Injection

Treatment of Prostate cancer, Breast cancer, Endometriosis, Premature puberty

Directions for Use

Luprocare Depot 3.75 gm Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Luprocare Depot 3.75 gm Injection contains Leuprorelin which works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and oestrogen in women. Thereby, Luprocare Depot 3.75 gm Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumour or causing it to shrink.  Also, Luprocare Depot 3.75 gm Injection is used to treat hormone-responsive breast cancer in pre and postmenopausal women. By reducing testosterone and oestrogen levels, Luprocare Depot 3.75 gm Injection delays the onset of puberty in children.

How Luprocare Depot 3.75 gm Injection Works

Luprocare Depot 3.75 gm Injection contains Leuprorelin, a synthetic hormone that works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and estrogen in women. Thereby, Luprocare Depot 3.75 gm Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumor or causing it to shrink.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Luprocare Depot 3.75 gm Injection

In men:

  • Muscle weakness
  • Bone pain
  • Inability to have an erection
  • Tiredness
  • Decreased interest in sex

In women:

  • Breast tenderness
  • Difficulty in sleeping
  • Headache
  • Vaginal dryness
  • Changes in breast size

In children:

  • Acne
  • Mood swings
  • Vaginal bleeding
  • Pain, redness, swelling or skin hardening at the injection site

What if I have taken an overdose of Luprocare Depot 3.75 gm Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to Luprocare Depot 3.75 gm Injection or any other medicines, please tell your doctor. Luprocare Depot 3.75 gm Injection is contraindicated in pregnant and breastfeeding women. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Luprocare Depot 3.75 gm Injection as it may cause birth defects. Luprocare Depot 3.75 gm Injection should be used with caution in children. You are advised to quit smoking as it may increase the risk of prostate cancer. You are recommended to avoid or limit consumption of alcohol with Luprocare Depot 3.75 gm Injection as it may increase the risk of bone density loss. Drive only if you are alert as Luprocare Depot 3.75 gm Injection may cause dizziness, drowsiness or vision disturbances.

Drug-Drug Interactions

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LeuprorelinIbutilide
Critical
LeuprorelinDofetilide
Critical

Drug-Drug Interactions

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LeuprorelinIbutilide
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Using ibutilide together with leuprolide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Ibutilide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinDofetilide
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking leuprolide with dofetilide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Dofetilide together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LeuprorelinVandetanib
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking Luprocare Depot 3.75 gm Injection 1's with Vandetanib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Vandetanib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinCisapride
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking leuprolide with cisapride can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Luprocare Depot 3.75 gm Injection 1's with Cisapride is not recommended, it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinCitalopram
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Coadministration of Luprocare Depot 3.75 gm Injection 1's and citalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's and citalopram together can possibly result in an interaction; they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinPimozide
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking Luprocare Depot 3.75 gm Injection 1's with Pimozide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinSaquinavir
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking leuprolide with Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinNilotinib
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Using nilotinib together with leuprolide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Nilotinib is not recommended, as it can result in an interaction. It can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LeuprorelinEliglustat
Critical
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking Leuprolide and Eliglustat together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Luprocare Depot 3.75 gm Injection 1's with Eliglustat together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LeuprorelinProcainamide
Severe
How does the drug interact with Luprocare Depot 3.75 gm Injection 1's:
Taking leuprolide with procainamide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Luprocare Depot 3.75 gm Injection 1's and procainamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, and saturated fat found in animal products, milk, and dairy products as they may increase the risk of prostate cancer.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Quit smoking to reduce the risk of prostate cancer.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.

Habit Forming

No

Therapeutic Class

GONADOTROPHIN-RELEASING HORMONE AGONIST
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Alcohol

Caution

Avoid or limit alcohol consumption with Luprocare Depot 3.75 gm Injection as it may increase the risk of bone density loss.

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Pregnancy

Unsafe

Luprocare Depot 3.75 gm Injection is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Luprocare Depot 3.75 gm Injection is contraindicated in breastfeeding women. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Luprocare Depot 3.75 gm Injection may cause dizziness, drowsiness or disturbance in the vision. Therefore, avoid driving if you experience any of these symptoms after taking Luprocare Depot 3.75 gm Injection.

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Liver

Caution

Take Luprocare Depot 3.75 gm Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Luprocare Depot 3.75 gm Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Luprocare Depot 3.75 gm Injection should be used for children under the supervision of a paediatric endocrinologist.

FAQs

Luprocare Depot 3.75 gm Injection contains Leuprorelin, a synthetic hormone that works similar to the natural hormone, gonadotropin-releasing hormone (GnRH) by acting on the pituitary gland and decreases the levels of testosterone in men and oestrogen in women. Thereby, Luprocare Depot 3.75 gm Injection is used in the treatment of prostate cancer by inhibiting the growth of tumour or causing it to shrink.
Luprocare Depot 3.75 gm Injection may stop menstrual periods. However, after 7 to 12 weeks of taking the final dose of injection, periods will resume. Please consult a doctor if you have any concerns regarding this.
Luprocare Depot 3.75 gm Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Luprocare Depot 3.75 gm Injection and inform your doctor if you have diabetes before taking Luprocare Depot 3.75 gm Injection.
Luprocare Depot 3.75 gm Injection may be used to treat endometriosis (tissue lining the uterus known as endometrium grows outside the uterus). Luprocare Depot 3.75 gm Injection reduces oestrogen levels and causes menopause temporarily. Thereby, shrink the tissue outside the uterus or stop its growth.
Luprocare Depot 3.75 gm Injection may decrease bone density, especially when used for the treatment of premature puberty in children. Therefore, regular monitoring of bone density is recommended while taking Luprocare Depot 3.75 gm Injection.
Luprocare Depot 3.75 gm Injection should be used with extreme caution in patients suffering from depression as it may worsen the condition. Therefore, inform your doctor if you have any history of depression before taking Luprocare Depot 3.75 gm Injection.
No, Luprocare Depot 3.75 gm Injection is not a chemotherapy medicine. It is a synthetic hormone which belongs to the class of medicines called gonadotropin-releasing hormone (GnRH) agonists.
Yes, Luprocare Depot 3.75 gm Injection is a hormonal medicine that works by altering reproductive hormones. It is not recommended for use during pregnancy as it can harm the fetus and may lead to abortion. If you are pregnant or planning to become pregnant, please inform your doctor.
The common side effects of Luprocare Depot 3.75 gm Injection are pain, redness, swelling, or skin hardening at the injection site, muscle weakness, bone pain, inability to have an erection, breast tenderness, headache, vaginal dryness, changes in breast size, acne, or mood swings. If any of these side effects persist or worsen, please consult your doctor.
Luprocare Depot 3.75 gm Injection belongs to the class of synthetic hormones used in the treatment of prostate cancer in men, endometriosis, and hormone-responsive breast cancer in women. Also, it is used to treat premature puberty in children.

Country of origin

India

Manufacturer/Marketer address

715, Gold Crest Business Center, L.T Road, Borivali-W, Mumbai 400092
Other Info - LUP0304

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