Lupisulin R 40IU/ml Solution for Injection is used to treat type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition in which glucose levels are elevated in the body. In type 1 diabetes, the body does not make enough insulin (a hormone essential for glucose metabolism). In type 2 diabetes, either the body stops producing enough insulin, or there is resistance to the action of insulin.

Lupisulin R 40IU/ml Solution for Injection contains 'Human Insulin'. It replaces the deficient hormone 'insulin' in patients with diabetes. Lupisulin R 40IU/ml Solution for Injection suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Lupisulin R 40IU/ml Solution for Injection ensures rapid and consistent sugar control. It starts to work within 30 min after injection, and its action lasts up to 8 hours.

Take Lupisulin R 40IU/ml Solution for Injection as prescribed by your doctor. A healthcare professional will teach you how to take the injection. It can cause some side effects, such as low blood sugar, swelling in your hands or feet, weight gain, or thickening of the skin at the injection site. Consult your doctor if any of these side effects persist or get worse.

Do not take Lupisulin R 40IU/ml Solution for Injection if you are allergic to insulin or have an episode of hypoglycemia (low blood sugar). Talk to your doctor if you have a history of liver or kidney diseases and if you are pregnant or breastfeeding. Also, inform your doctor if you are taking any other anti-diabetic medications. If you experience an episode of hypoglycemia, seek medical attention immediately.

Lupisulin R 40IU/ml Solution for Injection contains Human Insulin, which is a short-acting form of insulin. It helps lower blood sugar levels in both adults and children. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. Lupisulin R 40IU/ml Solution for Injection helps in improving glycemic control, which in turn decreases the risk of progression of complications of diabetes like damage to the retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer, and others. 

• Low blood sugar
• Swelling in your hands or feet
• Weight gain
• Thickening of the skin at the injection

Do not take Lupisulin R 40IU/ml Solution for Injection if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking Lupisulin R 40IU/ml Solution for Injection if you are pregnant or breastfeeding. Lupisulin R 40IU/ml Solution for Injection may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule. 

Drug-Drug Interactions: Lupisulin R 40IU/ml Solution for Injection may interact with antidiabetic medications such as thiazolidinediones (rosiglitazone and pioglitazone) and increase the risk of heart failure. It may also interact with antibiotics (levofloxacin, norfloxacin, and ofloxacin, etc), antidepressants, medications to treat high blood pressure (enalapril, lisinopril, captopril, losartan, valsartan, propranolol, and metoprolol), diuretics, medications used to treat heart diseases and cause hypoglycemia (low blood sugar).

Drug-Food Interactions: Try to avoid alcoholic beverages with Lupisulin R 40IU/ml Solution for Injection as it may alter your blood glucose levels.

Drug-Disease Interactions: Inform your doctor if you have kidney disease, liver disease, low blood sugar level (hypoglycemia), and low potassium level (hypokalaemia).

• ROSIGLITAZONE
• PIOGLITAZONE
• LEVOFLOXACIN
• NORFLOXACIN
• OFLOXACIN
• ENALAPRIL
• LISINOPRIL
• CAPTOPRIL
• LOSARTAN
• VALSARTAN
• PROPRANOLOL
• METOPROLOL

• Include foods rich in healthy carbohydrates, fibre, fruits, whole grains, and vegetables in your diet.
• Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
• Follow a healthy diet and walk for at least a few minutes to complement treatment with Lupisulin R 40IU/ml Solution for Injection.
• Maintain a healthy weight by exercising regularly.
• Rest properly, avoid stress by doing meditation or yoga.

If you feel any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.  

Diabetes mellitus: It is a metabolic disease that causes high blood sugar levels. Type 1 diabetes (juvenile diabetes) is an autoimmune disease in which the immune system attacks and destroys its own cells in the pancreas, thereby producing no insulin. It often occurs in childhood. Type 2 diabetes (adult-onset diabetes) occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas produces little or no insulin at all. Symptoms include frequent urination, increased thirst, hunger, and blurred vision. The treatment includes oral glucose-lowering medicines and insulin shots.