Lupinace Tablet is used to treat high blood pressure and heart failure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Lupinace Tablet lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Lupinace Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure. 

In some cases, you may experience headaches, ankle swelling, slow heart rate, and nausea. Lupinace Tablet may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery. Most of these side effects of Lupinace Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Even if your blood pressure becomes normal, you should not stop using Lupinace Tablet; doing so may worsen your condition. Let your doctor know if you have had or currently have any liver, kidney, or heart problems. During pregnancy and lactation, Lupinace Tablet should be only taken after consulting your doctor. You should regularly monitor your blood pressure and heart rate.

Lupinace Tablet is primarily used to treat hypertension or high blood pressure. In combination therapy, it is also prescribed with other drugs, like thiazide diuretics (water pills). Besides, Lupinace Tablet prevents congestive heart failure in combination with diuretics (water pills) and cardiac glycosides like digitalis. In these patients, Lupinace Tablet improves heart complications, increases survival, and reduces hospitalization frequency.

• Cough
• Dizziness
• Vision blurred
• Weakness
• Nausea (feeling sick)

Lupinace Tablet should not be given to the people allergic to Lupinace Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, tell your doctor if you have low blood pressure (hypotension),  heart disease, liver disease, kidney disease, or are currently on dialysis. Lupinace Tablet is not recommended in neonates and children with worse kidney functioning (glomerular filtration rate <30 mL/min). The level of raised bilirubin has been reported in some cases, so patients with liver diseases (like cirrhosis, jaundice, yellowing of skin/eye etc.) should take the Lupinace Tablet with caution. Do not take Lupinace Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness. Tell your doctor that, you are using Lupinace Tablet before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery.

Drug-Drug Interactions: Lupinace Tablet may interact with diuretics (water pills), potassium supplements, anti-diabetic drugs or insulin, high blood pressure-lowering pills (aliskiren), and lithium.

Drug-Food Interactions: Avoid intake of high potassium and sodium intake. Including these in your diet might increase level of potassium in your blood (hyperkalemia). Besides this, do not use salt substitutes or potassium supplements while taking Lupinace Tablet.

Drug-Disease Interactions: Lupinace Tablet should not be given in patients with angioedema (swelling), bone marrow suppression, congestive heart failure, haemodialysis, hyperkalaemia (high potassium level), low blood pressure (hypotension), liver disease and kidney dysfunction.

• ALISKIREN
• INSULIN
• LITHIUM

• Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
• Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
• Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
• If you are taking alcohol, then only one serving for women and two serving for men is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
• Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

• If hypotension occurs, the patient should be placed in the supine position and if necessary, should receive an intravenous infusion of normal saline.

High blood pressure: Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. High blood pressure (hypertension) can cause chest pain (angina), heart attack (when blood supply to the heart is blocked), brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.