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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Lupihist DM Plus Syrup is a combination medicine that belongs to the expectorant class. It is used to treat dry cough. This medicine works by preventing nerve signals from the brain's cough centre from reaching the muscles that cause coughing and thus reducing cough. You may experience common side effects like headache, dizziness, numbness, drowsiness, or nausea.

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lupihist DM Plus Syrup

Lupihist DM Plus Syrup is used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear the airways.

Lupihist DM Plus Syrup is a combination of three drugs: Chlorpheniramine maleate (antihistamine), Phenylephrine hydrochloride (decongestant), and Dextromethorphan hydrobromide (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, it helps to provide relief from dry cough.

Take Lupihist DM Plus Syrup as prescribed. Your doctor will recommend how often you need to take Lupihist DM Plus Syrup based on your medical condition. Some people may experience dry mouth, throat, or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Lupihist DM Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Lupihist DM Plus Syrup. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Lupihist DM Plus Syrup. Avoid using Lupihist DM Plus Syrup if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Lupihist DM Plus Syrup.

Uses of Lupihist DM Plus Syrup

Treatment of Dry cough

Directions for Use

Syrup: Check the label for directions before using it. Shake the bottle well before use. Take Lupihist DM Plus Syrup as prescribed by your doctor with the help of a measuring cup provided with the pack.Capsule/Tablet: Swallow it with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Lupihist DM Plus Syrup is a combination of three drugs: Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide. Lupihist DM Plus Syrup is a combination medicine belonging to a class of drugs called 'cough and cold preparations' primarily used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine hydrochloride is a decongestant that helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Lupihist DM Plus Syrup helps to relieve cough, cold and allergic symptoms.

How Lupihist DM Plus Syrup Works

Lupihist DM Plus Syrup is a combination of three drugs: Chlorpheniramine maleate (antihistamine), Phenylephrine hydrochloride (decongestant), and Dextromethorphan hydrobromide (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, it helps to provide relief from dry cough.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lupihist DM Plus Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

What if I have taken an overdose of Lupihist DM Plus Syrup

Take this medicine in the prescribed doses only. Overdose of Lupihist DM Plus Syrup may cause agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, and seizures. Seek immediate medical attention if you or your child experience any of these symptoms.

Drug Warnings

If you are allergic to Lupihist DM Plus Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Lupihist DM Plus Syrup. Lupihist DM Plus Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Lupihist DM Plus Syrup. Avoid taking Lupihist DM Plus Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Lupihist DM Plus Syrup.

Drug-Drug Interactions

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DextromethorphanSelegiline
Critical
DextromethorphanTranylcypromine
Critical

Drug-Drug Interactions

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DextromethorphanSelegiline
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Lupihist DM Plus Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Tranylcypromine with Lupihist DM Plus Syrup 60 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Isocarboxazid with Lupihist DM Plus Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanPargyline
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Pargyline and Lupihist DM Plus Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Lupihist DM Plus Syrup 60 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanRasagiline
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Rasagiline with Lupihist DM Plus Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Phenelzine and Lupihist DM Plus Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Lupihist DM Plus Syrup 60 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Lupihist DM Plus Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Furazolidone with Lupihist DM Plus Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Lupihist DM Plus Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Lupihist DM Plus Syrup 60 ml only after 14 days of stopping Furazolidone.
PhenylephrinePropofol
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Lupihist DM Plus Syrup 60 ml with Propofol may lead to increased levels of Lupihist DM Plus Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSevoflurane
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with Sevoflurane can increase the levels of Lupihist DM Plus Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods. 
  • Drink plenty of fluids to avoid a dry throat while you have a cough. This will also help loosen mucus.
  • Avoid citrus fruits, as they may worsen the cough. Eat fruits rich in water, such as pears, watermelon, peaches, and pineapples.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Lupihist DM Plus Syrup Substitute

Substitutes safety advice
  • Alex Sugar Free Syrup 100 ml

    1.39per tablet
  • Respicure D Syrup 100 ml

    by AYUR

    1.03per tablet
  • Alkof Junior Syrup 100 ml

    1.06per tablet
  • Eascof-D Sugar Free Mixed Fruit Syrup 100 ml

    by AYUR

    1.08per tablet
  • XL-90 Plus Cough Syrup 100 ml

    by XL9

    1.08per tablet
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Alcohol

Caution

Avoid consumption of alcohol with Lupihist DM Plus Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Lupihist DM Plus Syrup.

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Pregnancy

Caution

The safety of Lupihist DM Plus Syrup in pregnant women is unknown. Consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Lupihist DM Plus Syrup is excreted in human milk. Consult your doctor if you have any concerns; your doctor will decide if Lupihist DM Plus Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Lupihist DM Plus Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Lupihist DM Plus Syrup.

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Liver

Caution

Take Lupihist DM Plus Syrup with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Lupihist DM Plus Syrup with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Caution

Lupihist DM Plus Syrup is not recommended for children below 12 years of age. However, please consult a doctor before using Lupihist DM Plus Syrup in children.

FAQs

Lupihist DM Plus Syrup is used to treat dry cough.
Lupihist DM Plus Syrup contains Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.
Consult your doctor before taking Lupihist DM Plus Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Lupihist DM Plus Syrup 72 hours prior to the surgery.
It is not recommended to take Lupihist DM Plus Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, Lupihist DM Plus Syrup should be taken at least 14days after your last dose of anti-depressants.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, wait until then to take Lupihist DM Plus Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.
Lupihist DM Plus Syrup may rarely worsen the symptoms of glaucoma. Therefore, Lupihist DM Plus Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.
Lupihist DM Plus Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Lupihist DM Plus Syrup. Avoid consumption of alcohol with Lupihist DM Plus Syrup as it may increase drowsiness.
No, Lupihist DM Plus Syrup does not contain steroids. It contains an antihistamine (chlorpheniramine maleate), a decongestant (phenylephrine hydrochloride), and a cough suppressant (dextromethorphan hydrobromide).
Yes, Lupihist DM Plus Syrup may cause sleepiness or drowsiness. Therefore, drive or operate machinery only if you are alert.
No, Lupihist DM Plus Syrup will not be more effective if taken in more than the recommended dose. Avoid exceeding the recommended dose as it might cause an overdose leading to unpleasant side effects.
Consult the doctor if you are breastfeeding; your doctor will decide if Lupihist DM Plus Syrup can be taken by breastfeeding mothers or not.
Store Lupihist DM Plus Syrup at room temperature, in a dry place. Keep it out of sight and reach of children.
Lupihist DM Plus Syrup is not recommended for children below 12 years of age. However, please consult a doctor before using Lupihist DM Plus Syrup in children.
After taking Lupihist DM Plus Syrup, it is advised to wait for a while before drinking water.
Lupihist DM Plus Syrup should be taken as advised by the doctor. Talk to the doctor if you have any concerns.
No, Lupihist DM Plus Syrup is not a steroid. It is a cough suppressant used to treat dry cough.
No, Lupihist DM Plus Syrup is not an antibiotic. It is a combination medicine used to treat cough.
Lupihist DM Plus Syrup may cause side effects like dry mouth, throat, or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Lupihist DM Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - LUP0372

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