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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Loxonor 25mg Tablet is used to treat schizophrenia and manic depression (bipolar disorder). It contains Loxapine which works by blocking the effects of chemical messengers in the brain and helps improve mood, behaviour, and thoughts. In some cases, this medicine may cause side effects such as restlessness, sleepiness, abdominal pain, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition

LOXAPINE-25MG

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Loxonor 25mg Tablet

Loxonor 25mg Tablet is used to treat schizophrenia and manic depression (or bipolar disorder). Loxonor 25mg Tablet also treats short-term treatment of long-term aggression in people with Alzheimer's dementia and mentally disabled children. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused. Manic depression, or bipolar disorder, is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behaviour changes. 

Loxonor 25mg Tablet contains 'Loxapine', which works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping in improving mood, behaviour, and thoughts. Loxonor 25mg Tablet elevates the symptoms of the disease and prevents them from coming back. 

Take Loxonor 25mg Tablet as your doctor has prescribed it. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. In some cases, you may experience certain common side effects such as Parkinsonism, difficulty sleeping, sleepiness, depression, anxiety, restlessness, shortness of breath, abdominal pain, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Loxonor 25mg Tablet for as long as your doctor has prescribed. Do not take Loxonor 25mg Tablet if you are pregnant or breastfeeding unless prescribed. Loxonor 25mg Tablet causes drowsiness and dizziness; do not drive unless you are alert. Loxonor 25mg Tablet can be given to children if prescribed by the doctor for treating conduct disorder. Loxonor 25mg Tablet should not be given to children for treating schizophrenia or mania. Avoid consuming alcohol with Loxonor 25mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Loxonor 25mg Tablet

Treatment of Schizophrenia, Manic depression (bipolar disorder)

Medicinal Benefits

Loxonor 25mg Tablet is used in the treatment of certain mood disorders like schizophrenia. This drug makes a person think more clearly, be less nervous and live a normal life. Loxonor 25mg Tablet also decreases aggression and wishes to hurt yourself or other persons. It also helps in reducing hallucinations about the things that actually not present there. Being an antipsychotic drug, it works by restoring the balance of certain natural substances like dopamine in the brain.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Loxonor 25mg Tablet

  • Dizziness
  • Faintness.
  • Blurred vision.
  • Weakness.
  • Dry mouth.
  • Trouble in falling asleep or staying asleep.
  • Increased saliva.
  • Nausea.

Drug Warnings

Loxonor 25mg Tablet have some sedative effects, start within 20 to 30 minutes and lasted through 12 hours, so it is advised to avoid driving or doing such work that needs mental alertness. Loxonor 25mg Tablet can not be used in comatose patients or persons heavily dependent on barbiturates, alcohol, and narcotics. This medicine should not be used in people who are allergic to this medicine or any other component of the drug. Loxonor 25mg Tablet should be used with caution in elderly persons as they are at more risk of serious side effects of the medicine. Loxonor 25mg Tablet is not allowed to use for the treatment of dementia-related psychosis.  Loxonor 25mg Tablet can be given to children above 10 years if prescribed by the doctor for treating a mental condition like schizophrenia and bipolar disorder. Avoid consuming alcohol along with Loxonor 25mg Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Loxonor 25mg Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Inform your doctor before taking Loxonor 25mg Tablet if you have diabetes as Loxonor 25mg Tablet can cause an increase in blood sugar levels. Loxonor 25mg Tablet may not be suitable for people with a history of prolactin-dependant breast cancer as Loxonor 25mg Tablet increases the levels of prolactin. Loxonor 25mg Tablet should not be used in adults to treat dementia-related psychosis. 
 

Drug Interactions

Drug-Drug Interaction: Loxonor 25mg Tablet may have interaction with medicines used to treat schizophrenia and bipolar disorder (aripiprazole), anxiety disorders (lorazepam, diazepam, alprazolam), depression (citalopram, duloxetine, fluoxetine, escitalopram, trazodone, sertraline), allergy (diphenhydramine, hydroxyzine), mania (divalproex sodium), fits (gabapentin, clonazepam, lamotrigine, pregabalin ), pain (oxycodone, tramadol), asthma (albuterol), psychosis (quetiapine).
Drug-Food Interaction: Loxonor 25mg Tablet may interact with alcohol, obesity, and high cholesterol levels.
Drug-Disease Interaction: Loxonor 25mg Tablet may have interactions with dementia (memory loss), CNS depression, liver disease, seizures, low blood pressure, diabetes, lipid alterations, weight gain, parkinsonism, acute alcohol intoxication, neuroleptic malignant syndrome (occurs due to reaction with anti-psychotic drugs), Tardive dyskinesia (repetitive, involuntary movements), irregular heartbeat (with QT interval prolongation), kidney impairment/disease, blood abnormalities, lipid alterations, Priapism (prolonged erection of the penis), and hyperprolactinemia (higher levels of prolactin in the blood).

Drug-Drug Interactions Checker List

  • ALBUTEROL
  • GABAPENTIN
  • QUETIAPINE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • HYDROXYZINE
  • DIPHENHYDRAMINE
  • OXYCODONE
  • TRAMADOL
  • ESCITALOPRAM
  • SERTRALINE
  • TRAZODONE
  • DULOXETINE
  • FLUOXETINE
  • ARIPIPRAZOLE
  • LORAZEPAM
  • ALPRAZOLAM
  • CITALOPRAM
  • DIAZEPAM

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

While taking Loxonor 25mg Tablet, you may become more sensitive to extreme temperature conditions (like too hot or too cold temperature), so it is advisable to avoid getting too cold or too hot or becoming dehydrated, especially during summer. Drink plenty of fluid and water to cope with this condition. 

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganized thinking, loss of interest, lack of emotions, etc.

Manic depression (bipolar disorder): It is a serious brain disorder in which a person goes through unusual mood changes (mood swings) and frequent changes in his/her behaviour and thinking. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Loxonor 25mg Tablet as it may cause increased drowsiness and lower your blood pressure.

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Pregnancy

Unsafe

Avoid taking Loxonor 25mg Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Loxonor 25mg Tablet can pass into the breastmilk, so it is not safe to breastfeed while taking Loxonor 25mg Tablet. Consult your doctor before taking Loxonor 25mg Tablet; your doctor will decide whether Loxonor 25mg Tablet can be taken by breastfeeding mothers or not. Tell your doctor if your baby has symptoms of dizziness or tremor.

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Driving

Unsafe

Loxonor 25mg Tablet causes tiredness, dizziness and vision problems. Do not drive or operate machinery without consulting your doctor.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

The safety and efficacy of Loxonor 25mg Tablet are not established in children under the age of 18 years.

Country of origin

India
Other Info - LO87637

Author Details

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FAQs

Loxonor 25mg Tablet is used to treat schizophrenia and manic depression (or bipolar disorder). It is also used to treat aggression in people with Alzheimer's dementia and mentally disabled children.
Loxonor 25mg Tablet works by balancing the chemical messengers called neurotransmitters and blocking the effect of dopamine and serotonin located in the brain, thereby helps in improving mood, behaviour and thoughts.
Loxonor 25mg Tablet can cause tiredness, dizziness and vision problems. So, it is advisable not to drive or operate machinery without consulting your doctor. It may also lower your blood pressure on sudden standing leading to dizziness, so try to get up easily to avoid this.
Loxonor 25mg Tablet may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Loxonor 25mg Tablet. Diabetes patients should consult a doctor before taking Loxonor 25mg Tablet.
Yes, orthostatic hypotension could be a side-effect of Loxonor 25mg Tablet. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Loxonor 25mg Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.
Loxonor 25mg Tablet may make you sweat less, making you more likely to get heatstroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly.
Dry mouth could be a side-effect of Loxonor 25mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Loxonor 25mg Tablet is known to cause increased mortality in people who are elderly with dementia. So, please inform your doctor if you have dementia; before starting Loxonor 25mg Tablet.

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