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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lostat-H Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Losartan and Hydrochlorothiazide, which helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Also, it prevents excess salt absorption in the body, preventing fluid retention. Thus, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload). In some cases, it may cause side effects such as upper respiratory infections, dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough.
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Manufacturer/Marketer :

Blue Cross Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Lostat-H Tablet

Lostat-H Tablet is used treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. Lostat-H Tablet is a combination medication generally used when a single medicine is unable to control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

Lostat-H Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

You can take Lostat-H Tablet with food or an empty stomach. It should be swallowed whole with a glass of water. Your doctor will advise you on how often you take your tablets based on your medical condition. You may experience upper respiratory infections, dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough in some cases. Most of these side effects of Lostat-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Lostat-H Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Do not use if you are pregnant or planning to get pregnant; stop taking Lostat-H Tablet , and tell your doctor immediately. Besides this, you should not use the Lostat-H Tablet if you cannot urinate. If you have diabetes, do not use Lostat-H Tablet with any medication that contains aliskiren (a blood pressure medicine). Before taking the Lostat-H Tablet , tell your doctor if you have ever had liver disease, kidney failure, glaucoma (increased eye pressure), high or low magnesium or potassium levels in your blood, allergies or asthma, lupus (an autoimmune disease), or diabetes.

Uses of Lostat-H Tablet

Treatment of Hypertension (high blood pressure), Prevention of stroke.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lostat-H Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries). Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid retention).

How Lostat-H Tablet Works

Lostat-H Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lostat-H Tablet

  • Dizziness

  • Feeling tired

  • Nausea

  • Diarrhoea

  • Dehydration

  • Back pain

  • Cold/flu symptoms

What if I have taken an overdose of Lostat-H Tablet

Do not take more than the prescribed dose of Lostat-H Tablet as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Lostat-H Tablet should not be given to the people allergic to Lostat-H Tablet , have low blood pressure (less than 90 mm of Hg), or have had a heart attack, kidney disease, or liver disease. It should be used with caution in patients who have diabetes. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Do not consume alcohol with Lostat-H Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Lostat-H Tablet as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking Lostat-H Tablet . Drink a lot of fluids as Lostat-H Tablet can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.

Drug-Drug Interactions

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LosartanQuinapril
Severe
LosartanPerindopril
Severe

Drug-Drug Interactions

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LosartanQuinapril
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of Lostat-H Tablet 10's with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanPerindopril
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of Lostat-H Tablet 10's with Perindopril can increase of kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LosartanTizanidine
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of Lostat-H Tablet 10's with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
LosartanPotassium chloride
Severe
How does the drug interact with Lostat-H Tablet 10's:
Co-administration of Lostat-H Tablet 10's with Potassium chloride may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Potassium chloride together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce the intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not discontinue any medications without a doctor's advice.
LosartanRamipril
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of ramipril together with Lostat-H Tablet 10's may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Lostat-H Tablet 10's with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanCaptopril
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of Lostat-H Tablet 10's with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanLisinopril
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of Lostat-H Tablet 10's with Lisinopril can increase potassium levels.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Lisinopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LosartanEnalapril
Severe
How does the drug interact with Lostat-H Tablet 10's:
Using enalapril together with Lostat-H Tablet 10's may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Enalapril with Lostat-H Tablet 10's may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
LosartanAmiloride
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of amiloride with Lostat-H Tablet 10's may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Taking amiloride along with Lostat-H Tablet 10's may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanSpironolactone
Severe
How does the drug interact with Lostat-H Tablet 10's:
Coadministration of Lostat-H Tablet 10's with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Lostat-H Tablet 10's with Spironolactone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.

Drug-Food Interactions

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LOSARTAN-50MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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LOSARTAN-50MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Lostat-H Tablet 10's with potassium-rich foods can increase the risk or severity of side effects like weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Do not stop using any medications without first talking to your doctor. Avoid taking potassium-rich foods (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) along with Lostat-H Tablet 10's. If you experience any nausea, vomiting, weakness, confusion, tingling of the hands and feet, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Lostat-H Tablet Substitute

Substitutes safety advice
  • Losar-H Tablet 15's

    by Others

    18.39per tablet
  • Repace H Tablet 10's

    by Others

    15.30per tablet
  • Covance D Tablet 10's

    by Others

    16.74per tablet
  • Losakind-H Tablet 10's

    by Others

    8.37per tablet
  • Tozaar H Tablet 15's

    by AYUR

    15.03per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol and Lostat-H Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Lostat-H Tablet is not recommended during pregnancy. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Caution

Lostat-H Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this.

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Driving

Caution

Lostat-H Tablet causes drowsiness and dizziness, so drive only if you are alert

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Liver

Caution

Lostat-H Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Unsafe

Not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Caution

Lostat-H Tablet hasn’t been studied in children younger than 18 years of age. So, it shouldn’t be used in people younger than 18 years.

FAQs

Lostat-H Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.
Lostat-H Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.
Lostat-H Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
In case you have missed a dose of Lostat-H Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Lostat-H Tablet will lead to low blood pressure.
It is not recommended to take Lostat-H Tablet if you are pregnant as it can damage the unborn baby (may lead to fetal toxicity).
Yes, prolonged intake of Lostat-H Tablet can cause an increase in blood potassium level. So, patients taking Lostat-H Tablet should avoid taking supplements and food rich in potassium to avoid any unpleasant side-effect.
Yes, Lostat-H Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Lostat-H Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
You should not take Lostat-H Tablet if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, anuria (reduction or absence of urine) and pregnant women in their second or third trimesters. Besides this, avoid using Lostat-H Tablet (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.

Country of origin

India

Manufacturer/Marketer address

Peninsula Chambers, Peninsula Corporate Park, G.K Marg, Lower Parel (West), Mumbai - 400013, Maharashtra, INDIA.
Other Info - LOS0006

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