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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Lopsan P 8mg/500mg Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Losartan and Hydrochlorothiazide, which helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Also, it prevents excess salt absorption in the body, preventing fluid retention. Thus, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload). In some cases, it may cause side effects such as upper respiratory infections, dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough.
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Manufacturer/Marketer :

Sanjeevani Bio-Tech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lopsan P 8mg/500mg Tablet

Lopsan P 8mg/500mg Tablet is used treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. Lopsan P 8mg/500mg Tablet is a combination medication generally used when a single medicine is unable to control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

Lopsan P 8mg/500mg Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

You can take Lopsan P 8mg/500mg Tablet with food or an empty stomach. It should be swallowed whole with a glass of water. Your doctor will advise you on how often you take your tablets based on your medical condition. You may experience upper respiratory infections, dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough in some cases. Most of these side effects of Lopsan P 8mg/500mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Lopsan P 8mg/500mg Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Do not use if you are pregnant or planning to get pregnant; stop taking Lopsan P 8mg/500mg Tablet, and tell your doctor immediately. Besides this, you should not use the Lopsan P 8mg/500mg Tablet if you cannot urinate. If you have diabetes, do not use Lopsan P 8mg/500mg Tablet with any medication that contains aliskiren (a blood pressure medicine). Before taking the Lopsan P 8mg/500mg Tablet, tell your doctor if you have ever had liver disease, kidney failure, glaucoma (increased eye pressure), high or low magnesium or potassium levels in your blood, allergies or asthma, lupus (an autoimmune disease), or diabetes.

Uses of Lopsan P 8mg/500mg Tablet

Treatment of Hypertension (high blood pressure), Prevention of stroke.

Medicinal Benefits

Lopsan P 8mg/500mg Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries). Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid retention).

Side Effects of Lopsan P 8mg/500mg Tablet

  • Dizziness

  • Feeling tired

  • Nausea

  • Diarrhoea

  • Dehydration

  • Back pain

  • Cold/flu symptoms

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Lopsan P 8mg/500mg Tablet should not be given to the people allergic to Lopsan P 8mg/500mg Tablet, have low blood pressure (less than 90 mm of Hg), or have had a heart attack, kidney disease, or liver disease. It should be used with caution in patients who have diabetes. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Do not consume alcohol with Lopsan P 8mg/500mg Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Lopsan P 8mg/500mg Tablet as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking Lopsan P 8mg/500mg Tablet. Drink a lot of fluids as Lopsan P 8mg/500mg Tablet can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Drug Interactions

verifiedApollotooltip
HydrochlorothiazideCisapride
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Food Interactions

verifiedApollotooltip
LOSARTAN-50MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods, Fruit juices
Moderate

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

What if I have taken an overdose of Lopsan P 8mg/500mg Tablet

Do not take more than the prescribed dose of Lopsan P 8mg/500mg Tablet as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

You are recommended not to consume alcohol and Lopsan P 8mg/500mg Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Lopsan P 8mg/500mg Tablet is not recommended during pregnancy. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Caution

Lopsan P 8mg/500mg Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this.

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Driving

Caution

Lopsan P 8mg/500mg Tablet causes drowsiness and dizziness, so drive only if you are alert

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Liver

Caution

Lopsan P 8mg/500mg Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Unsafe

Not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Caution

Lopsan P 8mg/500mg Tablet hasn’t been studied in children younger than 18 years of age. So, it shouldn’t be used in people younger than 18 years.

Country of origin

India

Manufacturer/Marketer address

S.C.F-250,First Floor, Motor Market Manimajra, Chandigarh
Other Info - LO60201

Author Details

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FAQs

Lopsan P 8mg/500mg Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.
Lopsan P 8mg/500mg Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.
Lopsan P 8mg/500mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
In case you have missed a dose of Lopsan P 8mg/500mg Tablet, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Lopsan P 8mg/500mg Tablet will lead to low blood pressure.
It is not recommended to take Lopsan P 8mg/500mg Tablet if you are pregnant as it can damage the unborn baby (may lead to fetal toxicity).
Yes, prolonged intake of Lopsan P 8mg/500mg Tablet can cause an increase in blood potassium level. So, patients taking Lopsan P 8mg/500mg Tablet should avoid taking supplements and food rich in potassium to avoid any unpleasant side-effect.
Yes, Lopsan P 8mg/500mg Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Lopsan P 8mg/500mg Tablet. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
You should not take Lopsan P 8mg/500mg Tablet if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, anuria (reduction or absence of urine) and pregnant women in their second or third trimesters. Besides this, avoid using Lopsan P 8mg/500mg Tablet (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.

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