Lori Injection 2 ml belongs to a group of medications called benzodiazepine used to treat anxiety, muscle spasms, and epilepsy/seizures/fits. It can also be used as a sedative during surgery or dental procedure. Besides this, it is also used to manage alcohol withdrawal symptoms like agitation, tremor, or hallucinations. An anxiety disorder is a mental condition characterized by feelings of excessive fear or worry that affect an individual's daily activities.

Lori Injection 2 ml contains diazepam, which works by increasing levels of the calming chemical mediator known as gamma-aminobutyric acid (GABA) in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles.

Lori Injection 2 ml will be administered by a healthcare professional; do not self-administer. Sometimes, Lori Injection 2 ml may cause side effects, such as drowsiness, fatigue, confusion, unsteadiness, or dizziness. Most of these side effects of Lori Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have lung disease, muscle weakness (myasthenia gravis), sleeping disorder, severe liver disease, or problems with alcohol consumption or other prescription recreational drugs. Inform your doctor if you are pregnant or breastfeeding. Do not drive or operate machinery as Lori Injection 2 ml may reduce mental alertness. It is advisable to avoid alcohol after taking this medicine to prevent adverse effects such as dizziness, drowsiness, and difficulty concentrating.

Lori Injection 2 ml belongs to a group of medications called benzodiazepine used to treat anxiety, muscle spasms, and epilepsy/seizures/fits. It can also be used as a sedative during surgery or dental procedure. Besides this, it is also used to manage alcohol withdrawal symptoms like agitation, tremor, or hallucinations. Lori Injection 2 ml contains diazepam, which works by increasing levels of the calming chemical mediator known as gamma-aminobutyric acid (GABA) in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles.

• Drowsiness
• Feeling sleepy (sedation)
• Light-headedness
• Unsteadiness, or dizziness
• Confusion

Lori Injection 2 ml is not recommended for people with hypersensitivity to diazepam, other related benzodiazepines or any components present in Lori Injection 2 ml, people with a phobia (a fear of a particular object or situation), difficulty breathing, porphyria (a disorder of the blood brought on by a buildup of specific substances connected to the proteins in red blood cells), liver impairment, muscle weakness (myasthenia gravis), open-angle glaucoma or acute narrow-angle glaucoma unless patients are receiving appropriate therapy. Inform your doctor if you have suicidal thoughts, difficulty concentrating, sleep disorders, depression, breathing problems, history of alcohol/drug abuse, arteriosclerosis (narrowing of the blood vessels), lung, kidney, liver or heart problems. Concomitant use of opioids and benzodiazepines may result in profound sedation, respiratory depression, coma, and death.

Drug-Drug Interactions: Lori Injection 2 ml may interact with antidepressants (fluvoxamine, fluoxetine), antipsychotics (clozapine), antihistamines (cetirizine), general anaesthetics, sedatives, antibiotics (erythromycin, rifampicin),  muscle relaxants (suxamethonium, tubocurarine), strong pain killers (morphine), medications to lower high blood pressure (moxonidine), diuretics (hydrochlorothiazide), nitrates (hydralazine), antacids (cimetidine, omeprazole), pills to treat chronic alcoholism (disulfiram), antiepileptic medicines (phenobarbital, carbamazepine, phenytoin, primidone), anti-HIV drugs (amprenavir, ritonavir), anti-Parkinson’s drug (levodopa), anaesthetic medications (ketamine), asthma drugs (theophylline), medicines used to relieve symptoms when you stop taking opioids (lofexidine) and medications used to treat nausea and vomiting (nabilone).

Drug-Food Interactions: Grapefruit, grapefruit juice and caffeine-containing food or drinks should be avoided as they can affect the working of Lori Injection 2 ml.

Drug-Disease Interactions: Inform your doctor if you have a phobia (a fear of a particular object or situation), obsessions (a personality disorder), breathing disorders, myasthenia gravis (muscle disorder), sleep apnoea syndrome (a condition where breathing stops for a short period of time when you are asleep), porphyria (a disease of the blood), liver impairment and arteriosclerosis (a narrowing of the blood vessels).

• FLUOXETINE
• CLOZAPINE
• CETIRIZINE
• ERYTHROMYCIN
• SUXAMETHONIUM
• TUBOCURARINE
• MORPHINE
• PHENOBARBITAL
• HYDROCHLOROTHIAZIDE
• HYDRALAZINE
• CIMETIDINE
• OMEPRAZOLE
• CARBAMAZEPINE
• PRIMIDONE
• AMPRENAVIR
• RITONAVIR
• LEVODOPA
• KETAMINE
• THEOPHYLLINE
• LOFEXIDINE
• NABILONE
• RIFAMPICIN
• DISULFIRAM
• PHENYTOIN

• Yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction can help improve your mindfulness.
• De-stress by meditating, reading books, taking a nice bubble bath, or listening to relaxing music.
• Regular exercise can help reduce anxiety by generating endorphins and enhancing your sleep and self-image.
• Drink plenty of water to keep hydrated.
• Include a diet rich in whole grains, vegetables, and fruits.
• Limit your consumption of alcohol, coffee, added sugar, salt, and fat.

• The use of Lori Injection 2 ml may increase the risk of misuse, abuse, and addiction.  Therefore, before prescribing Lori Injection 2 ml and throughout the treatment, the patient's risk for misuse, abuse, and addiction should be assessed.
• Lori Injection 2 ml may cause withdrawal symptoms if treatment is stopped suddenly. Therefore, the dose should be gradually reduced to prevent withdrawal symptoms.

Anxiety Disorder: An anxiety disorder is a mental health disorder characterised by feelings of excessive fear or worry that affect an individual's daily activities. Anxiety disorders differ from normal feelings of anxiety and nervousness, involving excessive anxiety, fear or worry. Anxiety disorders can affect an individual’s job performance, school work and personal relationships.

Muscle spasms: Muscle spasms are sudden, uncontrollable movements of the muscle that can be unpleasant and painful. Muscle spasms can occur when the nerve impulses that regulate muscle action are damaged or disrupted. Symptoms include stiff joints, strange postures, trouble moving, and pain in the affected muscles and joints. Muscle spasms can be triggered by fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing.

Epilepsy/seizures/fits: Epilepsy is a chronic disorder characterised by seizures (fits) episodes. In this condition, a chemical change in the brain cells (neurons) leads to a sudden surge of electrical activity in the brain, followed by sudden jerky movements of limbs or a part of the body.

Sedation: Sedation is a state of sleep, relaxation or drowsiness brought on by an external substance such as a drug. Sedation is the alleviation of irritation, anxiety or agitation by administering a sedative drug. It is generally carried out to ease the process of a diagnostic procedure or surgery.

Alcohol withdrawal syndrome: After a period of heavy drinking, someone who stops consuming alcohol may experience symptoms of alcohol withdrawal. The severity of alcohol withdrawal symptoms might vary greatly. Symptoms could appear anywhere between two hours to four days after a person stops drinking. Symptoms include hallucinations, seizures, tremors, nausea, and migraine. Alcohol withdrawal frequently necessitates both medical attention and hospitalisation.