Lorbriqua 100 mg Tablet 30's
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Lorbriqua 100 mg Tablet belongs to the group of medicines that inhibit an enzyme called anaplastic lymphoma kinase (ALK). It is used to treat adults with advanced stages of lung cancer called non-small cell lung cancer (NSCLC). Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer.
Lorbriqua 100 mg Tablet contains the active substance Lorlatinib, a medicine used to treat adults with advanced stages of a form of lung cancer called non-small cell lung cancer (NSCLC). It works by inhibiting a type of enzyme called tyrosine kinase and triggers the death of cancer cells in patients with alterations in genes for ALK. Lorbriqua 100 mg Tablet is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase.
Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as diarrhoea, constipation, joint pain, weight gain, headache, rash, and muscle pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor before taking Lorbriqua 100 mg Tablet if you are pregnant or breastfeeding. Lorbriqua 100 mg Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Lorbriqua 100 mg Tablet as it could lead to increased dizziness. Lorbriqua 100 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Lorbriqua 100 mg Tablet is listed as pregnancy category D. Because Lorbriqua 100 mg Tablet can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Lorbriqua 100 mg Tablet . Consult your doctor if you are breastfeeding; your doctor will decide whether Lorbriqua 100 mg Tablet can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Lorbriqua 100 mg Tablet may affect male fertility. Talk to your doctor about fertility preservation before taking Lorbriqua 100 mg Tablet .
Lorbriqua 100 mg Tablet contains the active substance Lorlatinib, a medicine used to treat adults with advanced stages of a form of lung cancer called non-small cell lung cancer (NSCLC). Lorbriqua 100 mg Tablet is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase. It works by inhibiting a type of enzyme called tyrosine kinase and triggers the death of cancer cells in patients with alterations in genes for ALK.
Consult your doctor before taking Lorbriqua 100 mg Tablet if you are pregnant or breastfeeding. Lorbriqua 100 mg Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Lorbriqua 100 mg Tablet as it could lead to increased dizziness. Lorbriqua 100 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Lorbriqua 100 mg Tablet is listed as pregnancy category D. Because Lorbriqua 100 mg Tablet can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Lorbriqua 100 mg Tablet . Consult your doctor if you are breastfeeding; your doctor will decide whether the Lorbriqua 100 mg Tablet can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Lorbriqua 100 mg Tablet may affect male fertility. Talk to your doctor about fertility preservation before taking Lorbriqua 100 mg Tablet .
Drug-Drug Interactions: Lorbriqua 100 mg Tablet may interact with various medications, including medicines used to treat fungal infections (e.g. Ketoconazole, Itraconazole), medications used to treat bacterial infections/CYP3A4 inhibitors (e.g. Erythromycin), a drug used to treat irregular heartbeat and other heart problems. (e.g. Quinidine), medications used to treat severe pain (e.g. Alfentanil and Fentanyl), medicines used in organ transplantation to prevent organ rejection (e.g. Ciclosporin, Sirolimus, and Tacrolimus), medicines used to treat AIDS/HIV (e.g. Efavirenz, Cobicistat), medications used to treat migraine headaches (e.g. Dihydroergotamine, Ergotamine ), a drug used to treat depression or to help people quit smoking (e.g. Buproprion), and medication used to treat hepatitis C (e.g. Boceprevir).
Drug-Food Interactions: You must not drink grapefruit juice or eat grapefruit while on treatment with Lorbriqua 100 mg Tablet as they may change the amount of Lorbriqua 100 mg Tablet in your body.
Drug-Disease Interactions: Lorbriqua 100 mg Tablet should be used with caution in patients with liver disorders, kidney disorders, central nervous system (CNS) and heart disorders.
You will have blood tests before you start treatment and during your treatment. These tests check the level of cholesterol, triglycerides and the enzymes amylase or lipase in your blood before you start treatment with Lorbriqua 100 mg Tablet and regularly during treatment. You will have blood tests before you start treatment and during your treatment. These tests check the level of cholesterol, triglycerides and the enzymes amylase or lipase in your blood before you start treatment with Lorbriqua 100 mg Tablet and regularly during treatment.
Non-small cell lung cancer (NSCLC): Non-small cell lung cancer (NSCLC) is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer.
Alcohol
Caution
It is not known if alcohol interacts with Lorbriqua 100 mg Tablet . However, as a precautionary measure, you are recommended not to consume alcohol with the Lorbriqua 100 mg Tablet to avoid unpleasant side effects.
Pregnancy
Unsafe
Lorbriqua 100 mg Tablet is listed as pregnancy category D. Because Lorbriqua 100 mg Tablet can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Lorbriqua 100 mg Tablet .
Breast Feeding
Unsafe
Do not breastfeed for seven days after the last dose while taking this medicine. This is because it is unknown if the Lorbriqua 100 mg Tablet can pass into breast milk and could harm your baby.
Driving
Caution
Lorbriqua 100 mg Tablet moderately influences the ability to drive and use machines. Caution should be exercised when driving or operating machines, as patients may experience CNS effects.
Liver
Caution
Inform your doctor before receiving the Lorbriqua 100 mg Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.
Kidney
Caution
Inform your doctor before receiving the Lorbriqua 100 mg Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.
Children
Unsafe
Lorbriqua 100 mg Tablet is only indicated in adults, and it is not to be given to children and adolescents.
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