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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Loram 2.5 Tablet is used to treat high blood pressure. It contains Ramipril and Losartan which work by relaxing and widening the narrowed blood vessels. In some cases, this medicine may cause side effects such as headache, dizziness, dry cough, weakness, stomach pain, diarrhoea, indigestion, nausea and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Torrent Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Loram 2.5 Tablet

Loram 2.5 Tablet belongs to the group of medications called ‘antihypertensives’ used in the treatment of hypertension (high blood pressure). High blood pressure is a chronic (long-term) condition in which blood pressure is elevated persistently in higher than normal levels. If left untreated, this condition can increase the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat and other complications.

Loram 2.5 Tablet contains Ramipril and Losartan. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor and works by lowering the body’s production of substances that could narrow the blood vessels and increase blood pressure. Losartan is an angiotensin-II receptor blocker (ARB) that narrows the blood vessels increasing the blood pressure, therefore blocking angiotensin can result in the widening of the narrowed blood vessels. Together, Loram 2.5 Tablet allows the blood to flow more smoothly in the blood vessels.

You should take this medicine exactly as prescribed by the doctor. Loram 2.5 Tablet may cause side effects such as headache, dizziness, hypotension (abnormally low blood pressure), especially when you stand or sit up quickly, dry cough, weakness, stomach pain, diarrhea, indigestion, feeling or being sick, skin rash, chest pain, muscle cramps, hyperkalemia (increased potassium levels in the blood), and hypoglycemia (decreased glucose levels in the blood). If any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Loram 2.5 Tablet if you are allergic to any contents of it, have severe liver impairment, have angioedema (serious allergic reaction), having dialysis treatment, have renal artery stenosis (a kidney problem in which blood supply to the kidney is reduced), and have severe hypotension (abnormally low blood pressure). It is also not recommended for use in children, pregnant and breastfeeding women. The dose may have to be adjusted in elderly people. It is not advised to consume alcohol as it can increase dizziness. Loram 2.5 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Loram 2.5 Tablet

Treatment of Hypertension

Medicinal Benefits

Loram 2.5 Tablet is used in the treatment of hypertension. It works by lowering the body’s production of substances that could increase blood pressure and also widens narrowed blood vessels. It allows the blood to flow more smoothly in the blood vessels. It can reduce the risk of heart failure, stroke and delay worsening of kidney problems. It can also be given as a treatment for chronic heart failure. 

Directions for Use

Take Loram 2.5 Tablet as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Loram 2.5 Tablet

  • Dizziness
  • Hypotension (abnormally low blood pressure), especially when you stand or sit up quickly
  • Dry cough
  • Weakness
  • Stomach pain
  • Diarrhea
  • Indigestion
  • Feeling or being sick
  • Skin rash
  • Chest pain
  • Muscle cramps
  • Hyperkalemia (increased potassium levels in the blood)
  • Hypoglycemia (decreased glucose levels in the blood)

Drug Warnings

Before taking Loram 2.5 Tablet , inform your doctor if you have heart, kidney or liver problems. Loram 2.5 Tablet may sometimes cause a decrease in blood pressure than normal, especially in dehydrated people are taking diuretics (medicines to treat edema) and have low levels of sodium. Regularly check your blood pressure levels to avoid any risk. Loram 2.5 Tablet should also be used with caution in patients who are taking treatment for allergy, have hyperkalemia (high potassium levels), have adrenal gland problems and have systemic lupus erythematosus (a skin disease).

Drug Interactions

Drug-Drug Interactions: Loram 2.5 Tablet may interact with non-steroidal anti-inflammatory drugs (NSAIDs) (ibuprofen and indomethacin), pain killer(aspirin), medicines used for the treatment of low blood pressure, shock, cardiac failure, or allergies (ephedrine, noradrenaline), medicine used to treat long-term heart failure (sacubitril+valsartan), medicine that suppress immune system (ciclosporin, sirolimus, and everolimus), water pill (furosemide), medicines which can increase the amount of potassium in your blood (spironolactone, triamterene, amiloride, trimethoprim and trimethoprim+sulfamethoxazole), blood thinner (heparin), steroid medicine (prednisolone), medicine to treat gout (allopurinol), medicine to treat heart rhythm problems (procainamide), medicines used to treat cancer (temsirolimus and amifostine), antipsychotics, medicine used to treat type 2 diabetes (vildagliptin and insulin), medicine used to treat diarrhea (racecadotril), medicine to treat high blood pressure (aliskiren), and antidepressants (baclofen and lithium).

Drug-Food Interactions: Loram 2.5 Tablet may interact with alcohol and increase dizziness.

Drug-Disease Interactions: Loram 2.5 Tablet should not be used in patients with liver impairment, angioedema (serious allergic reaction), under dialysis treatment, renal artery stenosis (a kidney problem in which blood supply to the kidney is reduced) and severe hypotension (abnormally low blood pressure).

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • INDOMETHACIN
  • ASPIRIN
  • EPHEDRINE
  • NORADRENALINE
  • SACUBITRIL+VALSARTAN
  • CICLOSPORIN
  • SIROLIMUS
  • EVEROLIMUS
  • FUROSEMIDE
  • SPIRONOLACTONE
  • TRIAMTERENE
  • AMILORIDE
  • TRIMETHOPRIM
  • TRIMETHOPRIM+SULFAMETHOXAZOLE
  • HEPARIN
  • PREDNISOLONE
  • ALLOPURINOL
  • PROCAINAMIDE
  • TEMSIROLIMUS
  • INSULIN
  • RACECADOTRIL
  • ALISKIREN
  • BACLOFEN
  • LITHIUM

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • Limit alcohol intake. One serving for women and two servings for men is advisable.
  • Quit smoking as it is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food and drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Special Advise

  • Monitor your blood pressure regularly while using Loram 2.5 Tablet to make sure it is working properly. 
  • Your doctor may also monitor glucose levels, kidney function and electrolyte levels at regular intervals during the treatment with Loram 2.5 Tablet . 
  • You should not discontinue using Loram 2.5 Tablet without consulting your doctor.

Disease/Condition Glossary

Hypertension: It is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. It occurs when the blood’s force against the wall of blood vessels is too high. This condition can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes damage to the brain, kidneys and eyes. The risk of high blood pressure complications increases with the following: obesity, smoking, diabetes, alcohol intake, lack of physical inactivity, stress and kidney diseases.

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Alcohol

Caution

It is not advised to consume alcohol while taking Loram 2.5 Tablet as it can increase dizziness.

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Pregnancy

Unsafe

It is not recommended to take Loram 2.5 Tablet while you are pregnant (especially during the second and third trimesters) as it may be harmful to the unborn baby. Consult your doctor before the use of Loram 2.5 Tablet .

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Breast Feeding

Unsafe

It is not recommended to take Loram 2.5 Tablet while you are breastfeeding as it may cause harmful effects on the nursing baby. Consult your doctor before the use of Loram 2.5 Tablet .

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Driving

Caution

Loram 2.5 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Loram 2.5 Tablet should be given with caution in patients with a history of liver diseases. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Loram 2.5 Tablet should be given with caution in patients with a history of kidney diseases. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Loram 2.5 Tablet is not recommended for use in children as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102
Other Info - LOR0027

Author Details

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FAQs

Loram 2.5 Tablet is used to treat hypertension (high blood pressure).
Loram 2.5 Tablet contains Ramipril and Losartan. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor and works by lowering the body’s production of substances that could narrow the blood vessels and increase blood pressure. Losartan is an angiotensin-II receptor blocker (ARB) which narrows the blood vessels increasing the blood pressure, therefore blocking angiotensin can result in widening of the narrowed blood vessels. Together, Loram 2.5 Tablet can effectively reduce blood pressure and prevent complications associated with it.
Loram 2.5 Tablet can be safely taken as long as your doctor has prescribed it to you. High blood pressure is a life-long condition and you should not abruptly stop taking the medicine. Discontinuing Loram 2.5 Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in the future.
Please inform your doctor before surgery if you are taking Loram 2.5 Tablet as it needs to be stopped. Loram 2.5 Tablet might lower the blood pressure further if taken along with general anesthesia.
Loram 2.5 Tablet may cause side-effects such as headache, dizziness, hypotension (abnormally low blood pressure), especially when you stand or sit up quickly, dry cough, weakness, stomach pain, diarrhea, indigestion, feeling or being sick, skin rash, chest pain, muscle cramps, hyperkalemia (increased potassium levels in the blood) and hypoglycemia (decreased glucose levels in the blood). If any of these side-effects persist or get worse, inform your doctor immediately.
Loram 2.5 Tablet is probably safe for diabetic patients if it is prescribed by a doctor. Loram 2.5 Tablet protects the kidney and slows down the decrease of kidney function in hypertensive (high blood pressure) and type 2 diabetic patients.

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