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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Lonapil 0.25mg Tablet is used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. It may also be used to treat restless leg syndrome. It contains clonazepam, which works by increasing the level of a calming chemical in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, it aids in the treatment of seizures, panic disorder, and involuntary muscle spasms. In some cases, it may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CLONAZEPAM-0.25MG

Manufacturer/Marketer :

Arches Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lonapil 0.25mg Tablet

Lonapil 0.25mg Tablet belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Lonapil 0.25mg Tablet may also be used to treat restless leg syndrome. Epilepsy is a common neurological disorder that produces recurrent seizures. Seizures occur due to a sudden burst of electrical activity in the brain that disrupts its normal functioning. Panic disorder is an anxiety disorder characterised by frequent episodes of panic or fear.

Lonapil 0.25mg Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, Lonapil 0.25mg Tablet aids in the treatment of seizures, panic disorder, and involuntary muscle spasms.

Your doctor will advise you on how often you need to take this medicine based on your medical condition. In some cases, Lonapil 0.25mg Tablet may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Most of these side effects do not require medical attention and gradually resolve over time. However, please contact your doctor if the side effects are persistent.

Lonapil 0.25mg Tablet is a habit-forming drug. Therefore, before stopping this medicine, consult your doctor as it may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. If you are pregnant or breastfeeding, consult your doctor before taking Lonapil 0.25mg Tablet . Avoid drinking alcohol while taking Lonapil 0.25mg Tablet as it may cause increased dizziness and drowsiness. It is recommended not to drive or operate any machinery as Lonapil 0.25mg Tablet may cause dizziness, drowsiness, and problems with walking and coordination.

Uses of Lonapil 0.25mg Tablet

Treatment of Seizures, Panic disorder, Involuntary muscle spasms, Restless leg syndrome.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Solution: Shake the bottle well before use. Check the label for directions and take it in dose as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack.Orally disintegrating strip/Orally disintegrating tablet: Keep the strip/tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip/tablet with wet hands.

Medicinal Benefits

Lonapil 0.25mg Tablet belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Lonapil 0.25mg Tablet may also be used to treat restless leg syndrome. Lonapil 0.25mg Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. It decreases the feeling of nervousness, stress, and anxiety, which leads to a state of calmness and relaxation. Lonapil 0.25mg Tablet benefits people who struggle with anxiety and worries in daily life. Regular intake of the prescribed dose of Lonapil 0.25mg Tablet improves social life and the ability and performance at work, and general wellbeing.

How Lonapil 0.25mg Tablet Works

Lonapil 0.25mg Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, Lonapil 0.25mg Tablet aids in the treatment of seizures, panic disorder, and involuntary muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lonapil 0.25mg Tablet

  • Drowsiness
  • Dizziness
  • Fatigue
  • Problems with memory, walking, and coordination

What if I have taken an overdose of Lonapil 0.25mg Tablet

Do not take more than the prescribed dose of Lonapil 0.25mg Tablet as it may cause overdose. The symptoms of overdose include confusion, drowsiness or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Lonapil 0.25mg Tablet if you are allergic to clonazepam or any benzodiazepine class of drugs (diazepam, chlordiazepoxide, bromazepam, or flurazepam). Inform your doctor if you have lung disease, glaucoma, muscle weakness (myasthenia gravis), sleep apnoea (difficulty in sleeping), depression, mood problems, suicidal behaviour/thoughts, liver or kidney problems. Taking Lonapil 0.25mg Tablet with opioid medicines can cause severe drowsiness, breathing problems, coma, and death. Lonapil 0.25mg Tablet should be taken with extreme caution in patients with a history of alcohol or drug abuse. Do not stop taking Lonapil 0.25mg Tablet suddenly as it may cause withdrawal symptoms.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamPentazocine
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Taking Lonapil 0.25mg Tablet 10's with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Lonapil 0.25mg Tablet 10's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamPentazocine
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of Pentazocine with Lonapil 0.25mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Lonapil 0.25mg Tablet 10's with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamTramadol
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of Lonapil 0.25mg Tablet 10's with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Lonapil 0.25mg Tablet 10's and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamButorphanol
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of Butorphanol with Lonapil 0.25mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Although taking Lonapil 0.25mg Tablet 10's and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamNalbuphine
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of Nalbuphine with Lonapil 0.25mg Tablet 10's can make the side effects worse.

How to manage the interaction:
Although there is a possible interaction between Lonapil 0.25mg Tablet 10's and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamFentanyl
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of fentanyl and Lonapil 0.25mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Although combining Fentanyl and Lonapil 0.25mg Tablet 10's can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you feel sleepiness, loss of balance, or confusion. Do not stop taking any medication without consulting a doctor.
ClonazepamBuprenorphine
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
When Buprenorphine is used with Lonapil 0.25mg Tablet 10's, it may lead to significant adverse effects such as respiratory difficulties.

How to manage the interaction:
Co-administration of Buprenorphine alongside Lonapil 0.25mg Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you know how these drugs affect you. Do not discontinue any medications without consulting a doctor.
ClonazepamCodeine
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of Lonapil 0.25mg Tablet 10's with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Lonapil 0.25mg Tablet 10's with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.
ClonazepamMethadone
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Co-administration of Lonapil 0.25mg Tablet 10's with methadone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Lonapil 0.25mg Tablet 10's with methadone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without a doctor's advice.
ClonazepamMorphine
Severe
How does the drug interact with Lonapil 0.25mg Tablet 10's:
Using Morphine together with Lonapil 0.25mg Tablet 10's can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Lonapil 0.25mg Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise, which can help lower anxiety by releasing endorphins and improving your sleep and self-image.
  • Find humor in your daily life. Try to watch light-hearted shows to help relieve stress.
  • You can increase your mindfulness by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • Herbs like turmeric, ginger, and chamomile contain anti-inflammatory properties. Including this stuff in meals can reduce inflammation caused due to anxiety disorder.
  • Reduce alcohol, caffeine, added sugar, high salt, and high fat intake. Especially trans-fat may also help reduce inflammation.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon.
  • Try to spend time with your friends and family. Having a strong social network may help you lower the risk of anxiety.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Lonapil 0.25mg Tablet Substitute

Substitutes safety advice
  • Lonazep 0.25Mg Tablet 15's

    2.01per tablet
  • Clonotril-0.25 Tablet 15's

    2.01per tablet
  • Zapiz-0.25 Tablet 20's

    1.74per tablet
  • Petril-MD 0.25 Tablet 15's

    2.01per tablet
  • Zapiz-0.25 Tablet 10's

    3.47per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Lonapil 0.25mg Tablet to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness.

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Pregnancy

Unsafe

Lonapil 0.25mg Tablet belongs to pregnancy Category D. It is usually not recommended during pregnancy. However, consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Lonapil 0.25mg Tablet .

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Driving

Unsafe

Lonapil 0.25mg Tablet may cause dizziness, drowsiness and visual disturbances which may affect the ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Lonapil 0.25mg Tablet .

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Liver

Caution

Lonapil 0.25mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lonapil 0.25mg Tablet to be taken with caution, especially if you have a history of kidney disorders. The dose may have to be adjusted by your doctor.

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Children

Unsafe

It is not known whether Lonapil 0.25mg Tablet is safe or effective in treating conditions like panic disorder in children younger than 18 years. So, your doctor will decide whether Lonapil 0.25mg Tablet can be given to children less than 18 years of age or not.

FAQs

Lonapil 0.25mg Tablet is used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. It may also be used to treat restless leg syndrome.
Lonapil 0.25mg Tablet boosts gamma-aminobutyric acid levels (GABA) in the brain, which helps to ease anxiety, stop seizures (fits), and relax tense muscles.
Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness, or age-related health issues, which may require caution and an adjustment in the dose. Consult a doctor if you have any concerns.
Lonapil 0.25mg Tablet is a controlled and habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. However, if Lonapil 0.25mg Tablet is prescribed for more than 2-4 weeks, your doctor may reduce your dose gradually before completely stopping it to avoid withdrawal symptoms.
Do not stop taking Lonapil 0.25mg Tablet until instructed by your doctor. Stopping Lonapil 0.25mg Tablet may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. Your doctor may lower the dose gradually to prevent this.
Caffeine is a stimulant that may reduce the calming effects of Lonapil 0.25mg Tablet . So, it is advisable to avoid consuming caffeinated beverages like coffee, tea, cola, or chocolate containing caffeine.
The duration of Lonapil 0.25mg Tablet depends on the condition being treated. Your doctor will decide for how long you need to take Lonapil 0.25mg Tablet and may adjust the duration based on your age or specific condition. Please consult your doctor for the right duration of Lonapil 0.25mg Tablet .
Lonapil 0.25mg Tablet is generally safe when taken as prescribed by your doctor. However, it may cause side effects such as drowsiness, dizziness, and dependence if misused or taken long-term. Always follow your doctor's instructions to minimize risks.
No, Lonapil 0.25mg Tablet is not an opioid. It is a benzodiazepine, a class of medications primarily used to treat anxiety, panic disorders, and seizures. Opioids, on the other hand, are pain-relieving medications.
Lonapil 0.25mg Tablet is not an antidepressant. It is a benzodiazepine that helps reduce anxiety and seizures by calming the brain and nervous system. However, long-term use of benzodiazepines can sometimes lead to depression.
No, Lonapil 0.25mg Tablet is not classified as a narcotic. However, it is a prescription medication that belongs to the benzodiazepine class and is classified as a Schedule IV controlled substance. This means it has the potential to be habit-forming and may lead to misuse or dependence if not used as directed by your doctor.
Yes, Lonapil 0.25mg Tablet acts on nerve cells to help calm abnormal electrical activity in the brain, which may help reduce feelings of anxiety. However, Lonapil 0.25mg Tablet should only be taken for anxiety only if prescribed by your doctor.
Yes, Lonapil 0.25mg Tablet can make you sleepy because it is a benzodiazepine with sedative effects. It may cause drowsiness as a common side effect. If you continue to feel drowsy for a long time, please inform your doctor.
Lonapil 0.25mg Tablet is not commonly associated with weight gain. If you’re concerned about any weight changes or side effects, please consult your doctor.
No, it is not recommended to take Lonapil 0.25mg Tablet (a benzodiazepine) with hydrocodone (an opioid) as it may lead to serious side effects, such as severe sedation, respiratory distress, coma, and even death. Please consult your doctor before combining these medications.
Yes, you can take Lonapil 0.25mg Tablet with paracetamol if advised by the doctor, as they do not have significant drug-drug interactions. However, please consult with your doctor before taking Lonapil 0.25mg Tablet with paracetamol.
No, Lonapil 0.25mg Tablet is generally recommended for short-term use due to its potential for dependence and side effects. Please consult your doctor regularly to assess the need for continued use.
The common side effects of Lonapil 0.25mg Tablet include drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. If these side effects persist, please inform your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

No:45/4 1St Main road, Mangala Nagar, Porur, Chennai - 600 116, India.
Other Info - LON0135

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