How does Lomotil Tablet work?

Lomotil Tablet contains Diphenoxylate and Atropine. Diphenoxylate works by slowing down intestinal movements, thereby making the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine.

Does Lomotil Tablet cause dry mouth?

Dry mouth could be a side-effect of Lomotil Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Does Lomotil Tablet cause constipation?

Constipation might be a side-effect of Lomotil Tablet . Drink enough fluids and eat fibre-rich food if you experience constipation. Consult your doctor if the condition persists or worsens.

Can I take anti-depressants with Lomotil Tablet ?

Do not take anti-depressants, especially MAO inhibitors, along with Lomotil Tablet as it may cause headache, high blood pressure, and hyperthermia (high temperature). Consult your doctor before taking Lomotil Tablet with other medicines to avoid unpleasant side effects.

Is it safe to take Lomotil Tablet for longer durations?

Do not take Lomotil Tablet for longer durations unless prescribed. Generally, your condition will get better within 48hours of taking Lomotil Tablet . Talk to your doctor if there is no improvement even after taking Lomotil Tablet for 10 days.

Can Lomotil Tablet cause addiction?

Lomotil Tablet does not have the potentiality to be habit-forming or addictive when used as suggested by your doctor. Always follow the doctor’s instructions while taking Lomotil Tablet .

Can Lomotil Tablet cause dental problems?

Lomotil Tablet doesn’t have potentiality to cause dental problems. If you face dental problem or any difficulty while using Lomotil Tablet please consult your doctor.

What are the instructions for the storage and disposal of Lomotil Tablet ?

Lomotil Tablet should be stored in a cool and dry place away from sunlight and kept away from children’s reach. Dispose of unused or expired products through a drug take-back program or dispose them as advised by the pharmacist.

Can the use of Lomotil Tablet cause dizziness?

Lomotil Tablet may cause dizziness. So, do not drive or operate heavy machinery if you feel dizzy.

Can I drink alcohol while taking Lomotil Tablet ?

Avoid drinking alcohol while taking Lomotil Tablet . Alcohol can increase dizziness, drowsiness, and confusion.

Lomotil Tablet 20's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Lomotil Tablet is used to treat diarrhoea. It contains Diphenoxylate and Atropine, which works by slowing down the intestinal movements, thereby makes the stools more solid and less frequent. Also, it helps to prevent involuntary muscle movements in the intestine. In some cases, you may experience certain common side effects such as abdominal discomfort, nausea, vomiting, headache, dry mouth and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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About Lomotil Tablet

Lomotil Tablet belongs to the group of medicines called antidiarrheal used to treat diarrhoea. Diarrhoea is a condition characterized by loose and watery stools with a frequent need to have a bowel movement. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.

Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down the intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Atropine is added to prevent the abuse of diphenoxylate as higher doses may cause physical dependence.

You are advised to take Lomotil Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal discomfort, nausea, vomiting, headache, dry mouth and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Lomotil Tablet if you have a blockage in the intestines, ulcerative colitis, asthma, glaucoma, urination problems, Down’s syndrome, dehydration, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Lomotil Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Lomotil Tablet as it may cause increased dizziness and drowsiness. Lomotil Tablet should not be given to children below 13years as the safety and effectiveness have not been established.

Uses of Lomotil Tablet

Treatment of Diarrhoea.

Directions for Use

You can take Lomotil Tablet with or without food. Swallow Lomotil Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Lomotil Tablet belongs to the group of medicines called antidiarrheals used to treat diarrhoea. Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Together, Lomotil Tablet helps to treat diarrhoea.

How Lomotil Tablet Works

Lomotil Tablet is a combination of two drugs: Diphenoxylate (opioid agonist) and Atropine (anti-cholinergic). Diphenoxylate works by slowing down the intestinal movements, thereby makes the stools more solid and less frequent. Atropine helps to prevent involuntary muscle movements in the intestine. Atropine is added to prevent the abuse of diphenoxylate as higher doses may cause physical dependence.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lomotil Tablet

Abdominal discomfort
Nausea
Vomiting
Headache
Dry mouth
Dizziness

What if I have taken an overdose of Lomotil Tablet

Do not take more than the prescribed dose of Lomotil Tablet as it may cause overdose leading to breathing problems and may result in permanent brain damage. The symptoms of early overdose include blurred vision, weakness, slurred speech, fast heartbeat, fainting, slow breathing, feeling hot, seizure or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Lomotil Tablet if you are allergic to any of its contents; if you have obstructive jaundice, diarrhoea caused by bacteria or antibiotics. Do not take monoamine oxidase inhibitors (MAOI) with Lomotil Tablet . Inform your doctor before taking Lomotil Tablet if you have a blockage in the intestines, ulcerative colitis, asthma, glaucoma, urination problems, Down’s syndrome, dehydration, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Lomotil Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Lomotil Tablet as it may cause increased dizziness and drowsiness. Lomotil Tablet should not be given to children below 13years as the safety and effectiveness have not been established.

Drug-Drug Interactions

AtropineSecretin

Severe

AtropineTopiramate

Severe

Drug-Drug Interactions

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AtropineSecretin

Severe

How does the drug interact with Lomotil Tablet 20's:
When Secretin human is used with Lomotil Tablet 20's, the therapeutic efficacy of Secretin human can be decrease.

How to manage the interaction:
Although there is a possible interaction between Lomotil Tablet 20's and Secretin, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

AtropineTopiramate

Severe

How does the drug interact with Lomotil Tablet 20's:
When Lomotil Tablet 20's and Topiramate are taken together it can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Lomotil Tablet 20's and topiramate together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.

AtropinePotassium citrate

Severe

How does the drug interact with Lomotil Tablet 20's:
Taking potassium citrate oral tablets or capsules with Lomotil Tablet 20's may increase the irritating effects of potassium on stomach and upper intestine.

How to manage the interaction:
Taking Lomotil Tablet 20's with potassium citrate together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, consult the doctor. Do not discontinue any medications without consulting a doctor.

AtropinePotassium chloride

Severe

How does the drug interact with Lomotil Tablet 20's:
Co-administration of Lomotil Tablet 20's with Potassium chloride oral tablets or capsules can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Lomotil Tablet 20's and Potassium chloride, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact the doctor right away: severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting(especially with blood), decreased hunger, dark, tarry stools. Do not discontinue any medications without a doctor's advice.

AtropineHydromorphone

Severe

How does the drug interact with Lomotil Tablet 20's:
Using Hydromorphone together with Lomotil Tablet 20's may increase the risk and/or severity of some side effects (dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation).

How to manage the interaction:
Although taking Hydromorphone and Lomotil Tablet 20's together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: trouble peeing, feeling dizzy or sleepy, feeling confused or having trouble focusing, dry mouth, constipation, or feeling less mentally sharp. Do not discontinue any medications without consulting a doctor.

AtropineUmeclidinium bromide

Severe

How does the drug interact with Lomotil Tablet 20's:
Using Lomotil Tablet 20's together with umeclidinium may increase side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes).

How to manage the interaction:
Although taking Lomotil Tablet 20's and Umeclidinium bromide together can cause an interaction, it can be taken if a doctor has suggested it. If you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, rapid heartbeat, confusion, memory problems, and glaucoma - an eye disease that causes vision loss in one or both eyes. Do not stop using any medications without talking to a doctor.

AtropineZonisamide

Severe

How does the drug interact with Lomotil Tablet 20's:
Coadministration of Lomotil Tablet 20's and Zonisamide can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although taking Lomotil Tablet 20's and Zonisamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, or if you have reduced sweating or a fever, consult a doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.

AtropinePramlintide

Severe

How does the drug interact with Lomotil Tablet 20's:
Coadministration of Pramlintide with Lomotil Tablet 20's can increase the risk of reduced movement in the digestive system.

How to manage the interaction:
Taking Lomotil Tablet 20's with Pramlintide together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.

AtropineSolifenacin

Severe

How does the drug interact with Lomotil Tablet 20's:
When Lomotil Tablet 20's is used with solifenacin may cause side effects (drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems).

How to manage the interaction:
Co- administration of Lomotil Tablet 20's with solifenacin can lead to an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, blurred vision, dry mouth, heat intolerance, flushing, reduced sweating, trouble urinating, abdominal cramps, constipation, irregular heartbeat, disorientation, and memory issues, consult the doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Include bananas, apple, toast, and rice in your diet to firm the stools.
Stay hydrated by drinking plenty of fluids to compensate for electrolyte loss.
Clear broths and ORS can help provide essential electrolytes.
Avoid spicy, fried and processed foods.
Take ample rest.
Avoid the intake of foods which can trigger diarrhoea.
Do not consume contaminated food or water.
It is advised to intake plenty of fluids to compensate for the loss of electrolytes and salts due to diarrhoea.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

Alcohol

Unsafe

Avoid consuming alcohol while taking Lomotil Tablet as it may cause increased dizziness and drowsiness.

Pregnancy

Caution

Lomotil Tablet belongs to pregnancy category C. Please consult your doctor before taking Lomotil Tablet if you are pregnant; your doctor will prescribe Lomotil Tablet only if the benefits outweigh the risks.

Breast Feeding

Caution

Lomotil Tablet may pass into breastmilk. Consult your doctor before taking Lomotil Tablet ; your doctor will decide whether Lomotil Tablet can be taken by breastfeeding mothers or not.

Driving

Caution

Lomotil Tablet may cause dizziness and drowsiness. Do not drive or operate machinery if you feel dizzy or drowsy.

Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Lomotil Tablet if you have liver impairment/liver disease before taking Lomotil Tablet .

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or kidney impairment/kidney disease before taking Lomotil Tablet .