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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:47 PM IST

Lipaglyn Tablet is used to treat high triglyceride levels in type-2 diabetic patients. It contains Saroglitazar which reduces the synthesis of triglycerides and promotes glucose utilisation. In some cases, this medicine may cause side effects such as nausea, vomiting, weakness, dizziness, and fever. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

SAROGLITAZAR-4MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Lipaglyn Tablet

Lipaglyn Tablet is an insulin sensitiser used to treat diabetic dyslipidaemia/hypertriglyceridemia in type-2 diabetic patients, which is not controlled by statins (lipid-lowering agents) alone. Lipaglyn Tablet has both lipid and glucose-lowering effects in a single molecule, thereby helping lower blood triglycerides and blood glucose levels. Diabetic dyslipidaemia is characterised by increased triglyceride levels, low-density lipoproteins (LDL) and decreased high-density lipoprotein (HDL) levels. This condition is common in people with type-2 diabetes mellitus.
 
Lipaglyn Tablet contains ‘Saroglitazar’, which has dual Peroxisome Proliferator-Activated Receptor (PPAR)-α/γ agonist having a strong PPAR-alpha effect and moderate PPAR-gamma effect. PPAR-alpha reduces the synthesis and secretion of triglycerides and increases lipolysis and hepatic oxidation of fatty acids. It also induces an increase in the synthesis of HDL cholesterol. PPAR-gamma reduces the metabolic burden on the liver and muscle and promotes glucose utilisation. It improves post-absorptive insulin-mediated suppression of hepatic glucose output. Thereby, Lipaglyn Tablet helps in lowering blood triglycerides and blood glucose levels.
 
You are advised to take Lipaglyn Tablet for as long as your doctor has prescribed it, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach inflammation, nausea, vomiting, weakness, chest discomfort, dizziness, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant. It is not known if Lipaglyn Tablet is excreted into breastmilk; therefore, nursing mothers should avoid taking Lipaglyn Tablet . Lipaglyn Tablet should not be given to children as safety and effectiveness have not been established. Lipaglyn Tablet should be used with caution in patients with kidney or liver impairment and in elderly patients. Avoid alcohol consumption while taking Lipaglyn Tablet as it might cause unpleasant side effects. Lipaglyn Tablet might cause dizziness, so drive with caution. Inform your doctor about all the medications you are taking and your health condition to rule out any unpleasant side effects.

Uses of Lipaglyn Tablet

Treatment of Diabetic dyslipidaemia/hypertriglyceridemia

Medicinal Benefits

Lipaglyn Tablet is an insulin sensitiser used to treat diabetic dyslipidaemia/hypertriglyceridemia in type-2 diabetes, which is not controlled by statins alone. Lipaglyn Tablet has demonstrated a reduction of triglycerides (TG), Low-Density Lipoprotein (LDL) cholesterol, non-high-density Lipoprotein (non-HDL) cholesterol, Very Low-Density Lipoprotein (VLDL) cholesterol, and an increase in HDL cholesterol. It has also shown glycemic indices by lowering the fasting plasma glucose and glycosylated haemoglobin in diabetic patients. Lipaglyn Tablet has dual Peroxisome Proliferator-Activated Receptor (PPAR)-α/γ agonist having strong PPAR-alpha effect and moderate PPAR-gamma effect. PPAR-alpha reduces the synthesis and secretion of triglycerides and increases lipolysis and hepatic oxidation of fatty acids. It also induces an increase in the synthesis of HDL cholesterol. PPAR-gamma reduces the metabolic burden on the liver and muscle, promotes glucose utilisation, and improves post-absorptive insulin-mediated suppression of hepatic glucose output. Lipaglyn Tablet has both lipid and glucose-lowering effects in a single molecule; this helps in lowering blood triglycerides and blood glucose levels as well. It also helps in improving insulin resistance. Lipaglyn Tablet offers a superior safety profile, greater efficacy on lipid regulation, and excellent glycaemic control.

Side Effects of Lipaglyn Tablet

  • Gastritis (stomach inflammation)
  • Nausea
  • Vomiting
  • Asthenia (weakness)
  • Chest discomfort
  • Dizziness
  • Pyrexia (fever)

Directions for Use

Swallow Lipaglyn Tablet as a whole with a glass of water; do not break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Lipaglyn Tablet if you are allergic to any of the components. Inform your doctor if you notice rapid weight gain. Consult your doctor before taking Lipaglyn Tablet if you are pregnant. It is not known if Lipaglyn Tablet is excreted into breastmilk; therefore, nursing mothers should avoid taking Lipaglyn Tablet . Lipaglyn Tablet should not be given to children as safety and effectiveness have not been established. Lipaglyn Tablet might cause dizziness, so drive with caution. Avoid alcohol consumption while taking Lipaglyn Tablet as it might cause unpleasant side-effects. Lipaglyn Tablet should be used with caution in patients with type-2 diabetes having cardiovascular disease.

Therapeutic Class

ANTIDIABETICS

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.

  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.

  • Limit salt and sugar intake.

  • Avoid smoking and alcohol consumption. 

  • Choose healthy fats and cut down on trans-fat.

  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.

  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take stairs instead of elevators/lifts.

  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.

  • Follow a healthy diet and walk for at least 45 minutes to complement treatment with Lipaglyn Tablet .

  • Rest properly, avoid stress by doing meditation or yoga.

Habit Forming

No

How Lipaglyn Tablet Works

Lipaglyn Tablet contains ‘Saroglitazar’, which has dual Peroxisome Proliferator-Activated Receptor (PPAR)-α/γ agonist having a strong PPAR-alpha effect and moderate PPAR-gamma effect. PPAR-alpha reduces the synthesis and secretion of triglycerides and increases lipolysis and hepatic oxidation of fatty acids. It also induces an increase in the synthesis of HDL cholesterol. PPAR-gamma reduces the metabolic burden on the liver and muscle and promotes glucose utilisation. It improves post-absorptive insulin-mediated suppression of hepatic glucose output. Thereby, Lipaglyn Tablet helps in lowering blood triglycerides and blood glucose levels.

What if I have taken an overdose of Lipaglyn Tablet

Take Lipaglyn Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Lipaglyn Tablet to prevent unpleasant side effects.

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Pregnancy

Caution

Lipaglyn Tablet belongs to pregnancy category C. Consult your doctor before taking Lipaglyn Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Nursing mothers should avoid taking Lipaglyn Tablet as it is not known if Lipaglyn Tablet is excreted into breastmilk.

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Driving

Caution

Lipaglyn Tablet may cause dizziness. Therefore, drive or operate machinery only if you are alert.

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Liver

Caution

Lipaglyn Tablet should be used with caution in patients with liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Lipaglyn Tablet should be used with caution in patients with kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Lipaglyn Tablet is not recommended for children as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - LIP0201

Author Details

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FAQs

Lipaglyn Tablet is used to treat diabetic dyslipidaemia/hypertriglyceridemia in type-2 diabetic patients, which is not controlled by statins (lipid-lowering agents) alone.
Lipaglyn Tablet decreases triglycerides, LDL cholesterol and increases HDL cholesterol. It also helps in promoting glucose utilisation. Thereby, Lipaglyn Tablet improves insulin resistance, and lowers blood triglycerides and blood glucose levels.
Lipaglyn Tablet does not cause weight gain or oedema. However, inform your doctor if you notice rapid weight gain. Your doctor might assess you for fluid accumulation, volume-related events such as oedema and congestive heart failure.
Do not stop taking Lipaglyn Tablet without consulting your doctor. To treat your condition effectually, continue taking Lipaglyn Tablet for as long as your doctor has prescribed it.
Lipaglyn Tablet can be taken by elderly patients if prescribed by the doctor. However, Lipaglyn Tablet should be used with caution in geriatric patients.
Consult your doctor before taking Lipaglyn Tablet if you have cardiac problems. If prescribed, Lipaglyn Tablet should be used with caution in patients with type-2 diabetes having heart-related problems with episodic congestive heart failure. Regular monitoring for signs and symptoms of congestive heart failure in such patients is advised.
Lipaglyn Tablet should be swallowed as a whole with water. Do not crush or chew it.
Lipaglyn Tablet should be taken during pregnancy if prescribed by the doctor. Please consult the doctor if you are pregnant or think you may be pregnant.
Nursing mothers should not use Lipaglyn Tablet as it is unknown if Saroglitazar is excreted into the breast milk.
Lipaglyn Tablet may cause common side effects like stomach inflammation, nausea, vomiting, weakness, chest discomfort, dizziness, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult the doctor if any of the side effects persist or worsen.
You are recommended to avoid alcohol consumption while taking Lipaglyn Tablet to prevent unpleasant side effects.
Take the missed dose as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose at the regular time.
Lipaglyn Tablet may help increase HDL/good cholesterol and lower LDL/bad cholesterol.
Lipaglyn Tablet should not be taken by people who are allergic to any of its components. It should be used with caution in people with abnormal liver/kidney function or a history of myopathies (disease that affects skeletal muscles).

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