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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Linox Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of infection-causing bacteria and thereby helps reduce various bacterial infections of the lungs (pneumonia) and skin. Some of the common side effects include headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, indigestion and localized pain.
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Composition :

LINEZOLID-2MG

Manufacturer/Marketer :

Unichem International

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Linox Injection

Linox Injection belongs to the class of medicines called oxazolidinones used to treat bacterial infections of the lungs (pneumonia), and skin. It is also used to treat infections which are resistant to other antibiotics. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Linox Injection does not work against infections caused by the virus, including cold and flu.

Linox Injection contains Linezolid. It treats infection by stopping the growth of infection-causing bacteria. 

Linox Injection shows some common side-effects like thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, indigestion and localized pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.

Inform your doctor before receiving this injection if you are pregnant or planning pregnancy. Linox Injection passes into breastmilk and can cause diarrhoea and vomiting in infants; therefore, discontinue breastfeeding prior to and throughout the treatment. Avoid alcohol consumption while taking Linox Injection as it may cause increased dizziness. Linox Injection may cause dizziness and vision problems, so drive and operate machinery only if you are alert. Keep your doctor informed about your health condition and your ongoing medications to rule out any interactions.

Uses of Linox Injection

Treatment of Bacterial infections

Directions for Use

Linox Injection will be administered by a qualified healthcare professional; do not self-administer.

Medicinal Benefits

Linox Injection belongs to the class of medicines called oxazolidinones used to treat bacterial infections of the lungs (pneumonia), and skin. It is also used to treat infections which are resistant to other antibiotics. Linox Injection contains Linezolid. It treats infection by stopping the growth of infection-causing bacteria. 

How Linox Injection Works

Linox Injection contains Linezolid. It treats infection by stopping the growth of infection-causing bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Linox Injection

  • Thrush (fungal infection)
  • Headache
  • Metallic taste
  • Diarrhoea
  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Indigestion
  • Localized pain

What if I have taken an overdose of Linox Injection

Linox Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of Linox Injection may cause wheezing, chest tightness, seizures, swelling of the face, lips, tongue, or throat, and severe diarrhea. Your doctor will initiate necessary measures when an overdose is suspected.

Drug Warnings

Let your doctor know before receiving Linox Injection if you are allergic to any of its contents; Linox Injection should not be taken if you are taking or have taken monoamine oxidase (MAO) inhibitors in the last 14 days. Inform your doctor if you have high blood pressure, overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion or other mental problems. Inform your doctor if you have bruises or bleeding disorders, have anaemia (low red blood cells), are prone to infections, have a history of seizures, if you are on dialysis, have diarrhoea, kidney or liver problems. Consult your doctor immediately if you experience a throbbing headache, vision problems, loss of sensitivity or tingling/prickling sensation in arms and legs, persistent diarrhoea, nausea, vomiting, abdominal pain or rapid breathing. 

Drug-Drug Interactions

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LinezolidModafinil
Critical
LinezolidClomipramine
Critical

Drug-Drug Interactions

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LinezolidModafinil
Critical
How does the drug interact with Linox Injection 300 ml:
Coadministration of Linox Injection 300 ml with Modafinil can increase the levels of Modafinil and increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Modafinil with Linox Injection 300 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, excessive sweating, shortness of breath, chest pain or tightness, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidClomipramine
Critical
How does the drug interact with Linox Injection 300 ml:
When Clomipramine is taken with Linox Injection 300 ml, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Clomipramine and Linox Injection 300 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-contact a doctor immediately. Do not stop using any medications without a doctor's advice.
LinezolidEpinephrine
Critical
How does the drug interact with Linox Injection 300 ml:
Taking Linox Injection 300 ml with Epinephrine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Linox Injection 300 ml with Epinephrine is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidFluvoxamine
Critical
How does the drug interact with Linox Injection 300 ml:
Taking Linox Injection 300 ml with Fluvoxamine can increase the risk of serotonin syndrome( a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Linox Injection 300 ml with Fluvoxamine is not recommended but can be taken together if prescribed by a doctor. However, if you experience confusion, hallucination (seeing & hearing things that do not exist), seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor (shaking of hands & legs), incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medication without consulting a doctor.
LinezolidOxcarbazepine
Critical
How does the drug interact with Linox Injection 300 ml:
When Oxcarbazepine is taken with Linox Injection 300 ml, it can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Linox Injection 300 ml is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
LinezolidVortioxetine
Critical
How does the drug interact with Linox Injection 300 ml:
Co-administration of Linox Injection 300 ml with Vortioxetine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Linox Injection 300 ml with Vortioxetine can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
LinezolidTramadol
Critical
How does the drug interact with Linox Injection 300 ml:
Co-administration of Linox Injection 300 ml with Tramadol can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linox Injection 300 ml with Tramadol is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
LinezolidMirtazapine
Critical
How does the drug interact with Linox Injection 300 ml:
Using Linox Injection 300 ml together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Linox Injection 300 ml with Mirtazapine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidDuloxetine
Critical
How does the drug interact with Linox Injection 300 ml:
Taking Duloxetine with Linox Injection 300 ml can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Duloxetine with Linox Injection 300 ml is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
LinezolidMethylphenidate
Critical
How does the drug interact with Linox Injection 300 ml:
Taking Linox Injection 300 ml with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Linox Injection 300 ml with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Linox Injection 300 ml for at least 14 days. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can kill the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Linox Injection Substitute

Substitutes safety advice
  • Linoplus Iv Injection 300ml

    3.02per tablet
  • Linospan 600 mg Injection 300 ml

    2.24per tablet
  • Linowin 2 mg/ml Infusion 300 ml

    1.09per tablet
  • Adlid 2mg Infusion

    1.14per tablet
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Alcohol

Unsafe

Avoid consuming alcohol while taking Linox Injection as it may cause increased dizziness.

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Pregnancy

Caution

There is no sufficient and rigorous research on pregnant women. However, if you are pregnant, inform your doctor. Your doctor may prescribe this medicine only if the possible benefit outweighs the potential risk to the foetus.

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Breast Feeding

Caution

If you are a breastfeeding mother, inform your doctor before receiving this medicine. Linox Injection passes into breastmilk and can cause diarrhoea and vomiting in infants; therefore, discontinue breastfeeding prior to and throughout the treatment.

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Driving

Caution

Linox Injection may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Long-term treatment with Linox Injection may worsen your liver condition if you have liver problems. Dose adjustment may be needed. Please inform your doctor before taking Linox Injection if you have liver impairment/liver disease or a history of liver conditions.

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Kidney

Caution

Linox Injection does not require dose adjustment for kidney dysfunction as the majority of both drugs undergo nonrenal clearance. However, if you have kidney problems, inform your doctor before receiving this injection.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing Linox Injection for your children based on age and the condition of the child.

FAQs

Linox Injection belongs to the class of medicines called oxazolidinones used to treat bacterial infections of the lungs (pneumonia), and skin. It is also used to treat infections which are resistant to other antibiotics.
Linox Injection works by stopping the growth of infection-causing bacteria. Thus, it treats the infection.
Diarrhoea might be a side-effect of Linox Injection . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain while on treatment with Linox Injection , inform your doctor. Do not take anti-diarrheal medicine on your own.
Linox Injection may cause oral or vaginal thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth/throat or vagina. Consult your doctor if the condition persists or worsens.
Linox Injection may affect certain laboratory test results such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the lab technician that you are on treatment with Linox Injection .
Linox Injection may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102
Other Info - LIN0003

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