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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Levofloxcin Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria by inhibiting the gyrase enzyme and thereby helps reduce various bacterial infections. This medicine is not effective for treating viral infections. Common side effects include constipation, nausea, diarrhoea, headache, dizziness, light-headedness, pain, redness, and injection site reactions.
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Prescription drug

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Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Levofloxcin Injection

Levofloxcin Injection belongs to the class of 'antibiotics', primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Levofloxcin Injection is composed of 'Levofloxacin' that belongs to a class of quinolone antibiotics. It works by inhibiting an enzyme called gyrase, responsible for the growth and development of bacterial DNA. Thereby, inhibits bacterial growth and treats bacterial infection.

Levofloxcin Injection will be administered by a healthcare professional. Levofloxcin Injection may cause a few side effects, although not everybody gets them. Common side effects of Levofloxcin Injection include constipation, nausea, diarrhoea, headache, dizziness, light-headedness, trouble sleeping/insomnia, pain, redness, and swelling at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have any allergic reactions to medicines, liver/kidney problems, fits, diabetes, tendonitis (inflammation of the tendon, a tissue connecting muscle and bone), myasthenia gravis (muscular weakness), high blood pressure, low blood potassium (hypokalaemia), and mood disorders. Levofloxcin Injection should be used only with a doctor's advice during pregnancy and breastfeeding. Levofloxcin Injection may cause light-headedness/dizziness; in such cases, please do not drive until you are alert. Levofloxcin Injection may cause dizziness; hence avoid or limit alcohol consumption.

Uses of Levofloxcin Injection

Treatment of Bacterial infections

Medicinal Benefits

Levofloxcin Injection treats various bacterial infections, including infections of the lower respiratory tract (lungs), urinary tract (kidneys and bladder), skin, soft tissues, and prostate gland. It contains Levofloxacin, a quinolone antibiotic that inhibits bacterial DNA gyrase, an enzyme required for the replication, transcription, and repair of the DNA. Thereby, inhibits bacterial growth and treats bacterial infection. It is also used to treat anthrax (a rare but serious bacterial illness) and certain types of plague.

Directions for Use

Levofloxcin Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Levofloxcin Injection

  • Constipation 
  • Nausea
  • Diarrhoea 
  • Light-headedness
  • Dizziness
  • Headache
  • Trouble sleeping/insomnia
  • Pain, redness, and swelling at the injection site

Drug Warnings

Brief your medical history to the doctor if you are allergic to any of the components in Levofloxcin Injection . Let your doctor know if you have any allergic reactions to medicines, liver/kidney diseases, diabetes, fits, tendon problems, high blood pressure, hypokalaemia, and mood disorders before starting Levofloxcin Injection . Levofloxcin Injection can make myasthenia gravis worse; hence you should take Levofloxcin Injection only under a doctor's supervision. Inform your doctor if you are pregnant or breastfeeding before starting this medicine. Levofloxcin Injection may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol consumption to prevent any undesired effects like dizziness while undergoing treatment.

Drug Interactions

Drug-Drug Interaction: Levofloxcin Injection may interact with antibiotics (erythromycin, azithromycin), blood thinners (warfarin), nonsteroidal anti-inflammatory drugs, respiratory medication (theophylline), immunosuppressants (cyclosporine), heart-related medicines (digoxin), gout medicines (probenecid), antacids (cimetidine), medicines treating abnormal heart rhythm (quinidine), antidepressants (amitriptyline), antipsychotics, anti-diabetic drugs, and multivitamins with minerals.

Drug-Food Interaction: Alcohol consumption should be avoided to prevent adverse effects

Drug-Disease Interaction: Before taking Levofloxcin Injection , let your doctor know if you have any liver or kidney diseases, tendonitis, bursitis, fits, diabetes, myasthenia gravis, dialysis, high blood pressure, nerve problems, mood disorders (depression), aneurysm, blockage of the aorta or other blood vessels, and connective tissue disorders like Marfan syndrome and Ehlers-Danlos syndrome.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • AZITHROMYCIN
  • WARFARIN
  • THEOPHYLLINE
  • CYCLOSPORINE
  • DIGOXIN
  • PROBENECID
  • CIMETIDINE
  • QUINIDINE
  • AMITRIPTYLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Avoid sharing personal items like shaving razors.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Special Advise

  • Levofloxcin Injection can cause serious tendon problems and nerve damage; hence you should be cautious. If you experience any symptoms like severe headaches, extreme hunger, irritability, numbness, tingling, burning pain, confusion, agitation, and memory problems, please stop using this medicine and seek immediate medical advice.
  • Levofloxcin Injection  might produce false-positive urine screening results for opiates. Inform the laboratory staff that you are taking Levofloxcin Injection if you are due to undergo any tests. 
  • Levofloxcin Injection may cause mental health-related side effects; hence patients with mood disorders should take advice accordingly.
  • If you are diabetic, monitor your blood sugar levels regularly since Levofloxcin Injection may affect blood glucose levels.
  • Quinolone antibiotics like Levofloxacin may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) in electrocardiogram (ECG) in some patients.
  • Clostridium difficile-associated diarrhoea (CDAD) is reported during the usage of antibiotics. Please consult your doctor if you experience prolonged diarrhoea.

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have a thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, shortness of breath, chills, muscle pain, fatigue, and tiredness. Untreated bacterial infections may lead to serious life-threatening conditions like sepsis.

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Alcohol

Caution

Alcohol consumption may worsen the side effect of Levofloxcin Injection like dizziness. It is better to avoid alcohol while you are being treated with Levofloxcin Injection .

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Pregnancy

Caution

Please consult your doctor before taking Levofloxcin Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Levofloxcin Injection is excreted into breast milk. Please consult your doctor before taking Levofloxcin Injection if you are breastfeeding.

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Driving

Caution

Levofloxcin Injection may cause side effects like dizziness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Levofloxcin Injection to be taken with caution if you have a history of liver diseases/conditions.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Levofloxcin Injection .

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Children

Caution

Levofloxcin Injection should be used for children only when prescribed by a doctor The dose may depend on the child's age and body weight.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - LEV0114

Author Details

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FAQs

Levofloxcin Injection belongs to the class of 'antibiotics', primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Levofloxcin Injection is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Levofloxcin Injection should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver or kidney diseases, hypokalaemia, diabetes, joint or tendon problems (tendonitis, bursitis), mood disorders (depression), myasthenia gravis (muscle weakness), peripheral neuropathy (nerve damage), fits, aneurysm (weakening of an artery), blockage of the aorta or other blood vessels, high blood pressure, and connective tissue disorders like Marfan syndrome and Ehlers-Danlos syndrome.
Levofloxcin Injection may cause hypoglycemia (low blood sugar levels) or hyperglycemia (high blood sugar levels). Inform your doctor if you have diabetes and monitor your blood sugar levels regularly if prescribed.
Levofloxcin Injection can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Levofloxcin Injection if you are undergoing any vaccinations.
Antacids and multivitamins with minerals can decrease the efficacy of Levofloxcin Injection . Hence, it is recommended to take Levofloxcin Injection 2 to 4 hours before or 4 to 6 hours after taking magnesium/aluminium antacids, sucralfate, zinc or iron preparations, and multivitamins with minerals.
Diarrhoea can be a side-effect of Levofloxcin Injection . Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Levofloxcin Injection . Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Levofloxcin Injection therapy.

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