Lethyrox 50 mcg Tablet is used to indicate the treatment of hypothyroidism or low secretion of thyroid hormone. Hypothyroidism is a chronic condition when the thyroid gland does not make enough thyroid hormones to meet your body’s needs. 

Lethyrox 50 mcg Tablet contains Levothyroxine sodium, which works by replacing the body's normally produced thyroid hormone. It minimizes symptoms of low thyroid hormone-like unknown weight gain, fatigue, and sensitivity to the cold. 

In some cases, Lethyrox 50 mcg Tablet may cause side effects like headache, weight loss, diarrhoea, irritability and nervousness. Most of these side effects may not require medical attention and may be resolved gradually over time. However, if the side effects persist or worsen, consult the doctor.

Your doctor may prescribe calcium or vitamin D supplements alongside Lethyrox 50 mcg Tablet for your bone health. People affected with diabetes taking Lethyrox 50 mcg Tablet may have altered blood glucose control that may result in increased antidiabetic agents or insulin requirements. Hence, it is recommended that people with diabetes should contact a doctor and carefully monitor their glucose level after starting, changing or discontinuing thyroid hormone therapy.

Lethyrox 50 mcg Tablet is primarily indicated for the treatment of hypothyroidism or low secretion of thyroid hormone. It comprises levothyroxine, which is a synthetic thyroid hormone that is chemically similar to thyroxine, which is produced by our thyroid glands. Levothyroxine helps to replace missing thyroid hormones and/or relieve stress on the thyroid gland. Lethyrox 50 mcg Tablet minimizes symptoms of low thyroid hormones like unknown weight gain, fatigue, sensitivity to the cold and many more. Thus, it helps in replacing the body's own natural thyroid hormone, which is essential for maintaining both mental and physical health. 

• Irregular heartbeat (palpitations)
• Muscle spasm
• Headache
• Nervousness
• Irritability
• Sleeplessness
• Tremors
• Muscle weakness
• Increased appetite
• Weight loss
• Diarrhoea

Foods like soybean flour, cottonseed meal, cabbage, cauliflower, walnuts, dietary fibre, calcium and calcium-fortified juices may affect the working of Lethyrox 50 mcg Tablet . Hence, avoid the intake of these foods within several hours of dosing if possible. Lethyrox 50 mcg Tablet should not be administered to patients with acute myocardial infarction and high blood pressure patients. So, close clinical monitoring of heart function is recommended before taking Lethyrox 50 mcg Tablet .

Drug-Drug Interaction: Medicines like appetite suppressant (phentermine), acidity medicine (esomeprazole), anti-diabetic drug (metformin), calcium/vitamin D, neuro-related medicine (amphetamine/dextroamphetamine), Antidepressant(amitriptyline, imipramine, dosulepin), Beta Blockers (propranolol, atenolol and sotalol), Anti-convulsants (carbamazepine, primidone and phenytoin), interact with Lethyrox 50 mcg Tablet . So, if you are taking these medicines make sure you contact your doctor before taking Lethyrox 50 mcg Tablet .

Drug-Food Interaction: If you are taking any homoeopathic, ayurvedic, Unani or any OTC items let your doctor know about this. These medicines may interact with Lethyrox 50 mcg Tablet and affect its working. Besides this, absorption of Lethyrox 50 mcg Tablet may be decreased by foods like soybean flour, cottonseed meal, walnuts, dietary fibre, calcium and calcium-fortified juices. So, try to avoid these foods if possible.

Drug-Disease Interaction: Thyroid hormones increase the workload of the heart and oxygen consumption of the body. Hence, a Lethyrox 50 mcg Tablet should be taken with caution in the heart patients (cardiovascular disorders) like high blood pressure, chest pain (angina) and coronary artery disease. You should have regular monitoring of heart function. If chest pain occurs frequently contact the doctor so that doctor may reduce the dosage.

• Eating the right nutrients and taking a regular dose of your prescribed medications may help reduce your symptoms and improve your thyroid function. Iodine, zinc and selenium are beneficial for people with hypothyroidism. However, it’s best to avoid iodine and selenium supplements unless your doctor advises you to take them.
• In hypothyroidism, there is usually a loss of calcium (hypocalcemia) and Vitamin D in our body. In such a case, people affected with hypothyroidism should opt for calcium-enriched foods.
• People with hypothyroidism usually have a slower metabolism, and eating more protein may help boost your metabolism.
• Daily yoga and aerobics exercises can help in boosting the metabolism.
• People with hypothyroidism should prefer the intake of more vegetables, fruits and lean meats. These foods are low in calories and may help prevent weight gain.
• Avoid taking Goitrogens (agents which interfere with the normal function of the thyroid gland), which generally include soy foods (tofu), cabbage, broccoli, kale, cauliflower, spinach, sweet potatoes, cassava, peaches, strawberries, millet, pine nuts, peanuts, etc.

• Doses beyond the range may produce serious or even life-threatening manifestations of toxicity. Thus, if you forget to take Lethyrox 50 mcg Tablet anytime, take the medicine as soon as you remember to take it. However, if it is almost time for your next dose, you should avoid the skipped dose and continue with your regular regime as advised by your doctor.
• Lethyrox 50 mcg Tablet should not be used for the treatment of obesity or for weight loss.
• Patients with adrenaline or pituitary gland problems, heart diseases, diabetes, and clotting disorders should not take Lethyrox 50 mcg Tablet without consulting a doctor, as the dose may need to be adjusted.
• Diabetes patients taking Lethyrox 50 mcg Tablet should contact the doctor before starting this medicine as it may worsen glycaemic control and may result in increased antidiabetic pills or insulin therapy.
• Regular intake of Lethyrox 50 mcg Tablet may decrease bone mineral density, particularly in post-menopausal women. Hence, consult your doctor, who might prescribe the lowest dose possible for your bone health.
• If you are taking Lethyrox 50 mcg Tablet prior to any surgery, let your doctor know.
• Thyroid function tests are usually done on an empty stomach after overnight (6-8 hrs) fasting.
• Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Hypothyroidism/underactive thyroid: It is a chronic condition when the thyroid gland does not make enough thyroid hormones to meet your body’s needs. When there is a low level of thyroid hormones, our body’s functions and metabolism slow down. Symptoms of hypothyroidism include fatigue, increased sensitivity to cold, constipation, dry skin, unexplained weight gain, puffy face, hoarseness of voice and muscle weakness. There may be a loss of Calcium and Vitamin D in some cases of hypothyroidism.