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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:24 PM IST
Lescol XL 80 Tablet is used to lower raised cholesterol levels and reduce the risk of heart attack and stroke in the future. It contains Fluvastatin which works by inhibiting an enzyme that produces cholesterol and decreases the production of LDL (bad cholesterol) by the liver. In some cases, this medicine may cause side effects such as stomach pain, nausea, headache, indigestion, or difficulty sleeping. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

FLUVASTATIN-80MG

Manufacturer/Marketer

Novartis India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Lescol XL 80 Tablet

Lescol XL 80 Tablet belongs to the class of medicines called 'statins' primarily used to lower raised bad cholesterol and triglyceride (TG) levels. Lescol XL 80 Tablet also reduces the risk of heart attack and stroke in the future. High cholesterol known as hyperlipidemia or dyslipidemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged that finally contributes to coronary heart diseases, like stroke and heart attack. 

Lescol XL 80 Tablet contains Fluvastatin that works by inhibiting HMG-CoA reductase an enzyme that produces cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Thus, Lescol XL 80 Tablet reduces the risk of stroke or heart attack by preventing the release of excess cholesterol deposition in the major blood vessels of the brain and heart.

Take Lescol XL 80 Tablet as prescribed by your doctor. You are advised to take Lescol XL 80 Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience stomach pain, nausea, headache, indigestion, or difficulty sleeping. Most of these side effects of Lescol XL 80 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Lescol XL 80 Tablet or any other medicines, please tell your doctor. Avoid using Lescol XL 80 Tablet if you are pregnant or breastfeeding women and consult a doctor before taking Lescol XL 80 Tablet . You are advised to take effective birth control measures while taking Lescol XL 80 Tablet to avoid pregnancy. Avoid consumption of alcohol with Lescol XL 80 Tablet as it may increase the risk of liver damage. Avoid taking Lescol XL 80 Tablet if you have liver disease, including high levels of certain liver enzymes such as transaminases.  If you are about to undergo an operation, inform your doctor that you are taking Lescol XL 80 Tablet .

Uses of Lescol XL 80 Tablet

Treatment of Hyperlipidemia (high cholesterol)

Medicinal Benefits

Lescol XL 80 Tablet contains Fluvastatin used to lower bad cholesterol and triglyceride levels in patients whose cholesterol levels are not controlled by diet and exercise alone. Lescol XL 80 Tablet inhibits HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, Lescol XL 80 Tablet reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the brain and the heart's major blood vessels. 

Directions for Use

Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lescol XL 80 Tablet

  • Stomach pain
  • Nausea
  • Headache
  • Indigestion
  • Difficulty in sleeping
  • Myalgia (muscle pain)

Drug Warnings

If you are allergic to Lescol XL 80 Tablet or any other medicines, please tell your doctor. If you have thyroid disorder (hypothyroidism), serious infection, very low blood pressure, low blood potassium, diabetes, kidney, liver, or muscle problems, please inform your doctor before taking Lescol XL 80 Tablet . Avoid using Lescol XL 80 Tablet if you are pregnant or breastfeeding women and consult a doctor before taking Lescol XL 80 Tablet . You are advised to take effective birth control measures while taking Lescol XL 80 Tablet to avoid pregnancy. Avoid consumption of alcohol with Lescol XL 80 Tablet as it may increase the risk of liver damage. Maintain a low-fat diet along with Lescol XL 80 Tablet for effective results. If you are taking or have taken fusidic acid (antibiotic) orally or by an injection in the last 7 days, inform your doctor before taking Lescol XL 80 Tablet as this combination may cause severe muscle problems. Avoid taking Lescol XL 80 Tablet if you have liver disease, including high levels of certain liver enzymes such as transaminases.  If you are about to undergo an operation, inform your doctor that you are taking Lescol XL 80 Tablet . 

Drug Interactions

Drug-Drug Interaction: Lescol XL 80 Tablet may have interaction with other medicines used to lower bad cholesterol (gemfibrozil, niacin, cholestyramine), antifungal (fluconazole), anticonvulsant (phenytoin), antibiotic (rifampicin, fusidic acid), a medicine used to treat gout (colchicine), antidiabetic (glibenclamide), immunosuppressant (cyclosporine), blood thinners (warfarin, clopidogrel).

Drug-Food Interaction: Avoid alcohol consumption with Lescol XL 80 Tablet as it may increase the risk of liver problems.

Drug-Disease Interaction: If you have thyroid disorder (hypothyroidism), severe infection, very low blood pressure, low blood potassium, diabetes, kidney, liver, or muscle problems, please inform your doctor before taking Lescol XL 80 Tablet .

Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • NIACIN
  • CHOLESTYRAMINE
  • FLUCONAZOLE
  • PHENYTOIN
  • RIFAMPICIN
  • COLCHICINE
  • GLIBENCLAMIDE
  • CYCLOSPORINE
  • WARFARIN
  • CLOPIDOGREL
  • FUSIDIC ACID

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts, and cut down beverages, processed and sugary foods.
  • Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight as obesity also raises bad cholesterol and lowers good cholesterol.
  • Avoid smoking and alcohol consumption.

Special Advise

  • Lescol XL 80 Tablet may give abnormal blood test values for liver and muscle.
  • Regular blood tests are recommended while taking Lescol XL 80 Tablet to monitor cholesterol levels in the blood and liver functioning.
  • Prolonged use of Lescol XL 80 Tablet may affect your skeletal muscle causing myopathy and rhabdomyolysis. 
  • Regular monitoring of Liver function test (LFT) is required as there might be an increase in liver enzymes in rare cases. 

Disease/Condition Glossary

High cholesterol known as hyperlipidemia or dyslipidemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged that finally contributes to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body, i.e. good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol from our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke. 

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Alcohol

Unsafe

Avoid consumption of alcohol with Lescol XL 80 Tablet as it may increase the risk of liver damage.

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Pregnancy

Unsafe

Lescol XL 80 Tablet is a Category X pregnancy drug and is not recommended for pregnant women as it may cause harm to the unborn baby. So, if you are pregnant or planning for pregnancy, please inform your doctor before taking Lescol XL 80 Tablet .

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lescol XL 80 Tablet as it may be unsafe for the baby. However, please consult a doctor before taking Lescol XL 80 Tablet .

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Driving

Safe if prescribed

Lescol XL 80 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Lescol XL 80 Tablet is not recommended for patients with Liver diseases/conditions as it may worsen the condition.

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Kidney

Caution

Take Lescol XL 80 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Lescol XL 80 Tablet is not recommended for children below 10 years of age. If it is highly required, it has to be determined by the doctor.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - LES0011

Author Details

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FAQs

Lescol XL 80 Tablet is used to treat high cholesterol. It lowers bad cholesterol and triglyceride levels and reduces the risk of heart attack and stroke in the future.
Lescol XL 80 Tablet contains Fluvastatin which works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, Lescol XL 80 Tablet reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.
You are not recommended to take Lescol XL 80 Tablet with fusidic acid (antibiotic) as it may increase the risk of severe muscle problems called rhabdomyolysis (the breakdown of muscle tissue). Also, inform your doctor if you are taking or have taken fusidic acid (antibiotic) orally or by an injection in the last 7 days. However, please consult a doctor before taking Lescol XL 80 Tablet with any other medicines.
Lescol XL 80 Tablet should be used with caution in diabetic patients as it may increase blood sugar levels. Regular monitoring of blood sugar levels is recommended while taking Lescol XL 80 Tablet as it may increase the risk of developing diabetes. Also, inform your doctor before taking Lescol XL 80 Tablet if you are diabetic.
You are recommended to avoid eating foods rich in fat or cholesterol and caffeine as it may increase side effects.
Lescol XL 80 Tablet may be used to prevent or reduce the risk of a heart attack in certain patients with coronary artery disease (damage or blockage of coronary arteries due to build-up of plaque). Lescol XL 80 Tablet decreases the excess cholesterol deposition in the major blood vessels of the heart.
You are not recommended to stop taking Lescol XL 80 Tablet without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Lescol XL 80 Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Lescol XL 80 Tablet , please consult your doctor so that the dose may be gradually reduced.
High cholesterol occurs when excess cholesterol builds up in the blood, increasing the risk of heart disease and stroke. It can be caused by poor diet, lack of exercise, smoking, and genetics. Cholesterol is carried by LDL (bad cholesterol), which contributes to plaque build-up, and HDL (good cholesterol), which helps remove excess cholesterol. Managing cholesterol through lifestyle changes and medicine is key to reducing health risks.
You are recommended to take Lescol XL 80 Tablet as long as your doctor advises, as it is typically prescribed for long-term use and may need to be taken for lifelong. Do not stop the medication, as side effects may reoccur.
Yes, tiredness can be a possible side effect of Lescol XL 80 Tablet . Not everyone experiences this, but some individuals may feel more tired while taking it. Contact a doctor if you have any concerns.
You are recommended to avoid alcohol while taking Lescol XL 80 Tablet , as it may cause liver damage. Please, consult the doctor if you have any concerns.
Lescol XL 80 Tablet is generally safe for patients when taken as per the dose and duration advised by a doctor.
Lescol XL 80 Tablet should be taken as prescribed by your doctor. It is recommended to take it at the same time every day, with or without food. Always follow your doctor's guidance for the exact timing.
Lescol XL 80 Tablet causes side effects such as stomach pain, nausea, headache, indigestion, difficulty in sleeping, and myalgia (muscle pain). Most of these side effects are temporary and do not require any medical attention, as these will reduce over time. Consult a doctor, if these side effects persist for longer durations.

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