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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Lariago Injection is an anti-malarial medication used in the treatment of malaria and extraintestinal Amebiasis. This medicine contains chloroquine which causes the death of the parasite by increasing the concentration of a toxic compound in the parasite. Common side effects include nausea, vomiting, diarrhoea, stomach cramps, headache, hair loss, changes in mood, etc.
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Synonym :

CHLOROQUINE PHOSPHATE

Composition :

CHLOROQUINE-40MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lariago Injection

Lariago Injection belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. It may also be used to treat extraintestinal amebiasis/amoebiasis. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Extraintestinal amebiasis is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver.

Lariago Injection contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Thereby treats malaria ans extraintestinal amebiasis.

Your doctor will decide the dose and duration based on your medical condition. Common side effects of Lariago Injection include nausea, vomiting, diarrhoea, stomach cramps, headache, hair loss, changes in mood/confusion, vision changes/blurred vision, black or tarry stools, bleeding gums, and dizziness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you are allergic to any of the components in Lariago Injection. Inform your doctor if you have any liver or kidney problems, fits, heart diseases, hearing problems, vision-related issues, fits, and damaged retina or vision problems before starting Lariago Injection. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Lariago Injection may cause dizziness; hence do not drive or operate machinery until you are alert. Avoiding alcohol during the treatment is recommended to rule out any possibility of worsening side effects. Lariago Injection should be used for children only when prescribed by a doctor.

Uses of Lariago Injection

Treatment of Malaria and Extraintestinal Amebiasis

Directions for Use

Lariago Injection will be injected by a healthcare professional. Do not self-administer.

Medicinal Benefits

Lariago Injection contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is effective against parasitic species, including Plasmodium vivax, Plasmodium malariae, and susceptible strains of Plasmodium falciparum. Lariago Injection is useful in extending the interval between treatment and relapse in patients with malaria or vivax malaria. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Chloroquine also has off-label uses in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus.

How Lariago Injection Works

Lariago Injection contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Thereby treats malaria ans extraintestinal amebiasis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lariago Injection

  • Nausea 
  • Vomiting 
  • Diarrhoea 
  • Stomach cramps 
  • Headache 
  • Hair loss 
  • Changes in mood/confusion 
  • Vision changes/blurred vision 
  • Black or tarry stools 
  • Bleeding gums 
  • Dizziness 

What if I have taken an overdose of Lariago Injection

Lariago Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include, severe dizziness, fainting, and slow/irregular heartbeat. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Before using Lariago Injection, inform your doctor if you have recently used any prescription and non-prescription medications, including other anti-malarial drugs. Inform your doctor if you have any allergic reactions, liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency, electrolyte imbalance, psoriasis, alcoholism, porphyria, hearing problems, vision-related issues, fits, and damaged retina or vision problems. Please seek medical advice if you are pregnant or breastfeeding before taking Lariago Injection. This medicine may cause dizziness; hence drive or operate machinery only when you are alert. Do not consume alcohol while being treated with Lariago Injection.

Drug-Drug Interactions

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ChloroquineMesoridazine
Critical
ChloroquineSparfloxacin
Critical

Drug-Drug Interactions

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ChloroquineMesoridazine
Critical
How does the drug interact with Lariago Injection 30 ml:
Taking Lariago Injection 30 ml with Mesoridazine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Injection 30 ml with Mesoridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineSparfloxacin
Critical
How does the drug interact with Lariago Injection 30 ml:
Using Lariago Injection 30 ml together with sparfloxacin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Lariago Injection 30 ml with Sparfloxacin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquinePazopanib
Critical
How does the drug interact with Lariago Injection 30 ml:
Taking pazopanib with Lariago Injection 30 ml can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pazopanib with Lariago Injection 30 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ChloroquineBepridil
Critical
How does the drug interact with Lariago Injection 30 ml:
Using Lariago Injection 30 ml together with bepridil can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Lariago Injection 30 ml with Bepridil is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineSaquinavir
Critical
How does the drug interact with Lariago Injection 30 ml:
Using saquinavir together with Lariago Injection 30 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Lariago Injection 30 ml with Saquinavir is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineTelavancin
Critical
How does the drug interact with Lariago Injection 30 ml:
Using Lariago Injection 30 ml together with telavancin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Telavancin with Lariago Injection 30 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineThioridazine
Critical
How does the drug interact with Lariago Injection 30 ml:
When Thioridazine and Lariago Injection 30 ml are taken together, can increase the chance of a serious abnormal heart rhythm

How to manage the interaction:
Taking Lariago Injection 30 ml with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase beta
Critical
How does the drug interact with Lariago Injection 30 ml:
Using Lariago Injection 30 ml with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Lariago Injection 30 ml is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineAurothioglucose
Critical
How does the drug interact with Lariago Injection 30 ml:
Taking Aurothioglucose with Lariago Injection 30 ml can cause blood disorders and other severe side effects

How to manage the interaction:
Taking Aurothioglucose with Lariago Injection 30 ml is not recommended, as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineLevacetylmethadol
Critical
How does the drug interact with Lariago Injection 30 ml:
Using Levacetylmethadol together with Lariago Injection 30 ml can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Lariago Injection 30 ml with Levacetylmethadol is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Malaria:

  • Take nutritious food, including fresh fruits and vegetables, to help recover from malarial fever.

  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.

  • Include high-fibre foods like green leafy vegetables and fruits to aid digestion.

  • Take proper rest to help your body relax and heal faster.

  • Avoid or limit the intake of alcohol and caffeine.

Extra intestinal Amebiasis:

  • Include fruits, vegetables, whole-grain bread, low-fat dairy products, beans, lean meats, and fish in your diet.

  • Avoid alcohol consumption that can further damage your liver in liver abscess.

  • Wash your hands often to prevent infection.

  • Stay away from patients who are infected with amebiasis.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Lariago Injection Substitute

Substitutes safety advice
  • Lariago Injection 2 ml

    2.70per tablet
  • Tamquin 40mg Injection

    0.55per tablet
  • Troyquin DS 40mg Tablet

    2.17per tablet
  • Malswift 40mg Injection

    0.30per tablet
  • Bitaquine 40mg Injection

    0.42per tablet
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Alcohol

Caution

Avoid alcohol while using Lariago Injection since it can worsen your side effects.

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Pregnancy

Caution

There is limited information on how Lariago Injection affects pregnancy. Please seek medical advice if you are pregnant or planning to conceive. Your doctor will prescribe Lariago Injection only if the benefits outweigh the risks.

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Breast Feeding

Caution

Lariago Injection may be excreted into the breast milk when used during lactation. Please consult your doctor before starting Lariago Injection if you are a breastfeeding mother.

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Driving

Caution

Lariago Injection may make you feel dizzy or cause blurry vision. In such cases, do not drive or operate machinery until you are alert and have a clear vision.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Lariago Injection.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Lariago Injection.

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Children

Caution

Lariago Injection should be used for children only when prescribed by a doctor. Your doctor will decide the dose based on your child's age and body weight.

FAQs

Lariago Injection belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. It may also be used to treat extraintestinal amebiasis/amoebiasis. Lariago Injection treats malaria by increasing the concentration of a toxic compound in the parasite that leads to its death.
Lariago Injection may cause irreversible retinal damage with long-term therapy. Retinopathy (disease related to the retina) is also reported with Chloroquine usage. You may not be advised Lariago Injection by your doctor if you have vision changes or retina damage. If the doctor has prescribed you this medicine knowing your medical history, you may be further advised to take ophthalmological examinations, including visual acuity, expert slit-lamp, funduscopic, and visual field tests. If there are any changes in these examinations, you may be asked to discontinue the treatment.
Inform your doctor in advance if you have any liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency (a genetic enzyme deficiency), electrolyte imbalance, psoriasis, alcoholism, porphyria (a blood disorder), hearing problems, vision-related issues, fits, and damaged retina or vision problems before starting Lariago Injection. Also, let your doctor know if you have recently undergone treatment with other anti-malarial drugs.
It is advised not to use Lariago Injection for the long term since it may produce retinal toxicity leading to blindness.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - LAR0017

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