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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Kolibitor Injection 5 ml is used to treat bacterial infections. It contains Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection. Common side effects of Kolibitor Injection 5 ml may include abnormal heartbeats, headache, diarrhoea, skin rashes, nausea, thrush or candidiasis (a fungal infection that affects the mouth or vagina).
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Fusion Health Care Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Kolibitor Injection 5 ml

Kolibitor Injection 5 ml belongs to the class of medicines called antibiotics. It is used to treat or prevent lung infections caused by bacteria called Pneumocystis jirovecii and Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), ear infections such as otitis media, respiratory tract infections such as bronchitis, and nocardiosis, which can affect the skin, lungs and brain. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Kolibitor Injection 5 ml does not work against infections, flu or cold symptoms caused by the virus.

Kolibitor Injection 5 ml contains two antibiotics, Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection.

Kolibitor Injection 5 ml will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience abnormal heartbeats, headache, diarrhoea, skin rashes, nausea, thrush or candidiasis (a fungal infection that affects the mouth or vagina) as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid receiving Kolibitor Injection 5 ml if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor Injection 5 ml, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. You are recommended to avoid breastfeeding while on treatment with Kolibitor Injection 5 ml. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome.

Uses of Kolibitor Injection 5 ml

Treatment of Bacterial infections

Medicinal Benefits

Kolibitor Injection 5 ml is a combination of two antibiotics, Sulfamethoxazole and Trimethoprim. It is used to treat or prevent lung infections caused by a bacteria called Pneumocystis jirovecii and infections caused by a bacteria called Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media, and nocardiosis which can affect the skin, lungs and brain. Additionally, Kolibitor Injection 5 ml is used to treat brucellosis (a bacterial infection that spreads from animals to people) if other treatments are not effective and in combination with other agents in line with national treatment guidelines. These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thereby inhibiting the growth and multiplication of bacteria and stopping the spread of infection.

Directions for Use

Kolibitor Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kolibitor Injection 5 ml

  • Abnormal heartbeats
  • Headache
  • Diarrhoea
  • Skin rashes
  • Nausea
  • Thrush or candidiasis (a fungal infection that affects the mouth or vagina)

Drug Warnings

Avoid receiving Kolibitor Injection 5 ml if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor Injection 5 ml, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. You are recommended to avoid breastfeeding while on treatment with Kolibitor Injection 5 ml. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome. If you are elderly, malnourished or underweight, inform your doctor before receiving Kolibitor Injection 5 ml.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking antiviral and antiparkinson agents (amantadine), immunosuppressants (ciclosporin, azathioprine), anticancer drugs (methotrexate), antiparasitics (pyrimethamine), diuretic (spironolactone), a blood thinner (warfarin), anticonvulsant (phenytoin), antidiabetics (glibenclamide, tolbutamide, glipizide, repaglinide), medicines used to treat heart problems (digoxin, procainamide), anti-HIV drugs (lamivudine, zidovudine), steroid (prednisolone), antibiotic (rifampicin), folinic acid and contraceptives. 

Drug-Food interactions: No interactions found.

Drug-Disease Interactions: Avoid receiving Kolibitor Injection 5 ml if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), or severe liver or kidney problems. If you have bronchial asthma or severe allergies, porphyria (rare blood disorder), anaemia (lack of blood), glucose-6-phosphate dehydrogenase deficiency, phenylketonuria (build-up of an amino acid called phenylalanine in the body), malnourished or underweight, haematological disorders (serious blood disorders), kidney disease, high levels of potassium and abnormally low levels of sodium in the blood, inform your doctor before receiving Kolibitor Injection 5 ml.

Drug-Drug Interactions Checker List

  • AMANTADINE
  • CICLOSPORIN
  • AZATHIOPRINE
  • METHOTREXATE
  • PYRIMETHAMINE
  • SPIRONOLACTONE
  • WARFARIN
  • PHENYTOIN
  • GLIBENCLAMIDE
  • TOLBUTAMIDE
  • GLIPIZIDE
  • REPAGLINIDE
  • DIGOXIN
  • PROCAINAMIDE
  • LAMIVUDINE
  • ZIDOVUDINE
  • PREDNISOLONE
  • RIFAMPICIN
  • FOLINIC ACID

Habit Forming

No

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Kolibitor Injection 5 ml to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids daily while taking Kolibitor Injection 5 ml.
  • Avoid alcohol consumption as it may increase adverse effects.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and causes infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.

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Alcohol

Consult your doctor

The interaction of Kolibitor Injection 5 ml with alcohol is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Consult your doctor

Kolibitor Injection 5 ml may harm the foetus. Therefore, if you are pregnant or planning pregnancy, inform your doctor before receiving Kolibitor Injection 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Avoid breastfeeding while on treatment with Kolibitor Injection 5 ml due to its potential risk of bilirubin displacement and kernicterus (brain damage). If you are a breastfeeding mother, please inform your doctor before receiving Kolibitor Injection 5 ml.

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Driving

Consult your doctor

Limited information is available on the effect of Kolibitor Injection 5 ml on driving. Please discuss with your doctor before driving or operating machinery after receiving Kolibitor Injection 5 ml.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Kolibitor Injection 5 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Kolibitor Injection 5 ml is contraindicated in patients with severe liver disease.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Kolibitor Injection 5 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Kolibitor Injection 5 ml is contraindicated in patients with severe kidney disease.

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Children

Caution

Kolibitor Injection 5 ml is contraindicated in children less than two months of age (less than six weeks) due to the risk of bilirubin displacement and kernicterus (brain damage).

Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - KOL0091

Author Details

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FAQs

Kolibitor Injection 5 ml is used to treat Bacterial infections.
Kolibitor Injection 5 ml is a combination of two antibiotics, Trimethoprim and Sulfamethoxazole. These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thereby inhibiting the growth and multiplication of bacteria, it stops the spread of infection.
Kolibitor Injection 5 ml may cause diarrhoea as a common side effect. Drink plenty of fluids and eat fibre-rich food if you experience diarrhoea. However, if the condition persists or worsens, or if you notice blood or mucus in your stools, inform your doctor immediately.
Kolibitor Injection 5 ml is not used to treat viral infections. Kolibitor Injection 5 ml is a combination of antibiotics that is used to treat only bacterial infections. If you have a viral infection, please consult a doctor so that appropriate medication may be prescribed.

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