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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 2:46 PM IST
Koftrodex Syrup 100 ml is a combination medicine which belongs to the class of expectorants. It is used in the treatment of wet/productive cough. This medicine works by increasing the volume of fluid in the airways, reducing the stickiness of mucus, and removing it from the airways. Common side effects include nausea, diarrhoea, vomiting, stomach discomfort, sweating, muscle cramps, dizziness, and headache.
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About Koftrodex Syrup 100 ml

Koftrodex Syrup 100 ml belongs to the class of medicines called 'expectorants' primarily used to treat cough associated with mucus. Coughing (dry or productive) is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.

Koftrodex Syrup 100 ml is a combination of four drugs, namely: Ambroxol (mucolytic agent), Desloratadine (antihistamine) Guaifenesin (expectorant), and Menthol (cooling agent). Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Guaifenesin works by increasing the volume of fluid in the airways, reducing the stickiness of mucus, and helping to remove it from the airways. Desloratadine works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Menthol produces a cooling sensation and provides relief from minor throat irritation.

Take Koftrodex Syrup 100 ml as prescribed. You are advised to take Koftrodex Syrup 100 ml for as long as your doctor has prescribed it based on your medical condition. Some people may experience drowsiness, dry mouth, headache, dizziness, tiredness, nausea, vomiting, and stomach upset. Most of these side effects of Koftrodex Syrup 100 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Koftrodex Syrup 100 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Koftrodex Syrup 100 ml. Koftrodex Syrup 100 ml is not recommended for children unless advised by a doctor. Drink plenty of fluids while taking Koftrodex Syrup 100 ml to loosen mucus. Drive only if you are alert after taking Koftrodex Syrup 100 ml as it may cause dizziness or drowsiness in some people. Avoid alcohol consumption while taking Koftrodex Syrup 100 ml as it might cause increased dizziness.

Uses of Koftrodex Syrup 100 ml

Treatment of Cough

Medicinal Benefits

Koftrodex Syrup 100 ml contains Ambroxol, Desloratadine, Guaifenesin, and Menthol used to treat a cough with mucus. Ambroxol is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Guaifenesin is an expectorant that increases the volume of fluid in the airways, reduces the stickiness of mucus, and helps to remove it from the airways. Desloratadine is an anti-allergic drug that blocks the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation.

Side Effects of Koftrodex Syrup 100 ml

  • Drowsiness
  • Dry mouth
  • Headache
  • Dizziness
  • Tiredness
  • Nausea
  • Vomiting
  • Stomach upset

Directions for Use

Take Koftrodex Syrup 100 ml with or without food as advised by your doctor. Check the label for directions before using Koftrodex Syrup 100 ml. Shake the bottle well before use and take it with the help of a measuring cup that is provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Koftrodex Syrup 100 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Koftrodex Syrup 100 ml. Koftrodex Syrup 100 ml is not recommended for children unless advised by a doctor. If you are suffering from a kidney or liver problem, please inform your doctor before taking Koftrodex Syrup 100 ml. Drink plenty of fluids while taking Koftrodex Syrup 100 ml to loosen mucus. Drive only if you are alert after taking Koftrodex Syrup 100 ml as it may cause dizziness or drowsiness in some people. 

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough. It helps loosen mucus. 
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches, and pineapples.

Habit Forming

No

How Koftrodex Syrup 100 ml Works

Koftrodex Syrup 100 ml is a combination of four drugs, namely: Ambroxol (mucolytic agent), Desloratadine (antihistamine) Guaifenesin (expectorant), and Menthol (cooling agent). Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Guaifenesin works by increasing the volume of fluid in the airways, reducing the stickiness of mucus, and helping to remove it from the airways. Desloratadine works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Menthol produces a cooling sensation and provides relief from minor throat irritation.

What if I have taken an overdose of Koftrodex Syrup 100 ml

Do not take more than the prescribed dose of Koftrodex Syrup 100 ml as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid alcohol consumption with Koftrodex Syrup 100 ml as it may increase dizziness and drowsiness.

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Pregnancy

Caution

The safety of Koftrodex Syrup 100 ml in pregnant women is unknown. Therefore, it is given to pregnant women only if doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Koftrodex Syrup 100 ml is excreted in human milk. Koftrodex Syrup 100 ml is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Koftrodex Syrup 100 ml may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Koftrodex Syrup 100 ml.

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Liver

Caution

Take Koftrodex Syrup 100 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Koftrodex Syrup 100 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Koftrodex Syrup 100 ml should be used with caution in children if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - KOF0214

Author Details

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FAQs

Koftrodex Syrup 100 ml belongs to the class of medicines called expectorants primarily used to treat cough associated with mucus.
Koftrodex Syrup 100 ml contains Ambroxol, Desloratadine, Guaifenesin and Menthol. Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Guaifenesin increases the volume of fluid in the airways, reduces the stickiness of mucus, and helps to remove it from the airways. Desloratadine blocks the action of histamine, a substance responsible for causing allergic reactions. Menthol produces a cooling sensation and provides relief from minor throat irritation.
Koftrodex Syrup 100 ml may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Koftrodex Syrup 100 ml to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
Koftrodex Syrup 100 ml should be used with caution in asthma patients as it causes allergic reactions. Therefore, if you have asthma, it is recommended to inform your doctor before taking Koftrodex Syrup 100 ml.
You are recommended to take Koftrodex Syrup 100 ml for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after using Koftrodex Syrup 100 ml for 1 week, please consult your doctor.
You are not recommended to stop taking Koftrodex Syrup 100 ml without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Koftrodex Syrup 100 ml for as long as your doctor has prescribed it and if you experience any difficulty while taking Koftrodex Syrup 100 ml, please consult your doctor.
Koftrodex Syrup 100 ml is not designed to treat chronic cough or asthma. It is primarily used for coughs that involve mucus (wet cough). Since most asthma-related coughs are dry and non-productive, Koftrodex Syrup 100 ml may not be effective for asthma or chronic cough. These conditions require specific treatments to address inflammation and airway narrowing. Please consult your doctor to determine the underlying cause and the appropriate treatment.
It is essential to be cautious when taking Koftrodex Syrup 100 ml alongside other cold or allergy medications. Medications with similar effects to Koftrodex Syrup 100 ml may increase the risk of side effects or interactions. Always consult your doctor for advice on which medications are safe to take together to avoid unwanted effects or overdose.
To ensure safe usage of Koftrodex Syrup 100 ml, follow these simple steps. Take the recommended dose, never take an overdose, and inform your doctor if you become pregnant while using this medication. Monitor your body's response and report any side effects. Also, avoid consuming alcohol while taking this medication. By following these guidelines, you'll maximize the benefits of Koftrodex Syrup 100 ml and protect your health.
Pregnant or breastfeeding women should consult their doctor before using Koftrodex Syrup 100 ml, as its safety during these periods is not well-established. Before prescribing, your doctor will determine whether the potential benefits outweigh the risks.
If you miss a dose of Koftrodex Syrup 100 ml, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.
Some people may experience side effects such as drowsiness, dry mouth, headache, dizziness, tiredness, nausea, vomiting, or stomach upset while using Koftrodex Syrup 100 ml. These side effects are usually mild and go away on their own over time, not requiring medical attention. However, if any side effects persist, worsen, or become bothersome, please consult your doctor for further advice and management.

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