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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Kofarest-LS Syrup is used to provide relief from cough associated with bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), emphysema (damage of air sacs in the lungs) and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist. It contains Levosalbutamol, Ambroxol hydrochloride, and Guaiphenesin. Levosalbutamol works by relaxing muscles and widening the airways of the lungs. Ambroxol hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby helping to cough out phlegm easily. Guaiphenesin increases the volume of fluid in the airways, reduces mucus's stickiness, and helps remove it from the airways. Together, Kofarest-LS Syrup helps relieve the cough.

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in last 90 days
Prescription drug

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Synonym :

AMBROXOL HYDROCHLORIDE+GUAIPHENESIN+LEVOSALBUTAMOL

Manufacturer/Marketer :

Centaur Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Kofarest-LS Syrup is used to provide relief from cough associated with bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), emphysema (damage of air sacs in the lungs) and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection.

Kofarest-LS Syrup is a combination of three drugs, namely Levosalbutamol (bronchodilator), Ambroxol hydrochloride (mucolytic agent), and Guaiphenesin (expectorant). Levosalbutamol works by relaxing muscles and widening the airways of the lungs. Ambroxol hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby helping to cough out phlegm easily. Guaiphenesin increases the volume of fluid in the airways, reduces the stickiness of mucus, and helps to remove it from the airways. Together, Kofarest-LS Syrup helps relieve the cough.

Kofarest-LS Syrup is for paediatric use. Your doctor will recommend how often your child needs to take Kofarest-LS Syrup based on his/her medical condition. Kofarest-LS Syrup may cause common side effects such as nausea, vomiting, indigestion, diarrhoea, headache, dry mouth or throat. Most of these side effects of Kofarest-LS Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If your child is allergic to Kofarest-LS Syrup or any other medicines, please tell your doctor. If your child is suffering from fits or has a history of fits, please inform the doctor before using Kofarest-LS Syrup as it may increase the risk of recurrent fits. Keep your doctor informed about your child’s health condition and medications to rule out any interactions/side effects.

Treatment of Cough
Shake the bottle well before use. Check the label for directions before using it. Give the prescribed dose to your child by mouth using the dropper provided with the pack.

Kofarest-LS Syrup contains Levosalbutamol, Ambroxol hydrochloride, and Guaiphenesin, which are used to treat coughs associated with mucus. Levosalbutamol is a bronchodilator that relaxes muscles and widens the airways of the lungs. Ambroxol hydrochloride is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby helping to cough out easily. Guaiphenesin is an expectorant that works by increasing the volume of fluid in the airways, reducing the stickiness of mucus and helping to remove it from the airways. Together, Kofarest-LS Syrup helps relieve the cough.

Kofarest-LS Syrup is a combination of three drugs, namely Levosalbutamol (bronchodilator), Ambroxol hydrochloride (mucolytic agent), and Guaiphenesin (expectorant). Levosalbutamol works by relaxing muscles and widening the airways of the lungs. Ambroxol hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby helping to cough out phlegm easily. Guaiphenesin increases the volume of fluid in the airways, reduces the stickiness of mucus, and helps to remove it from the airways. Together, Kofarest-LS Syrup helps relieve the cough.
Store in a cool and dry place away from sunlight
  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Headache
  • Dry mouth or throat
Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Kofarest-LS Syrup may include bleeding from the stomach or duodenum, decreased motility or constipation, dizziness or drowsiness, eye irritation, fatigue, gastrointestinal discomfort, gastrointestinal tract irritation, headache, hypokalaemia, nausea, nervousness, peritonitis, respiratory tract irritation, skin irritation, sleeplessness, tachycardia, tremor, and ulceration. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

If your child is allergic to Kofarest-LS Syrup or any other medicines, please tell your doctor. If your child is suffering from fits or has a history of fits, please inform the doctor before using Kofarest-LS Syrup as it may increase the risk of recurrent fits. If your child has kidney, liver or heart problems, inform your doctor before using Kofarest-LS Syrup .

verifiedApollotooltip
GuaifenesinProcarbazine
Severe
LevosalbutamolLevobunolol
Severe

Drug-Drug Interactions

GuaifenesinProcarbazine
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
-

How to manage the interaction:
Co-administration of Kofarest-LS Syrup 100 ml with Procarbazine can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
LevosalbutamolLevobunolol
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
Taking Kofarest-LS Syrup 100 ml with levalbuterol may reduce the benefits of both medications.

How to manage the interaction:
Although there is a possible interaction, Kofarest-LS Syrup 100 ml can be taken with Levobunolol if prescribed by the doctor. Do not discontinue the medications without consulting doctor.
LevosalbutamolCocaine
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
Taking Kofarest-LS Syrup 100 ml with Cocaine may cause irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction, Kofarest-LS Syrup 100 ml can be taken with Cocaine if prescribed by the doctor. Do not discontinue the medications without consulting doctor.
LevosalbutamolPropranolol
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
Coadministration of propranolol and Kofarest-LS Syrup 100 ml can increase the risk of breathing problems.

How to manage the interaction:
Although there is an interaction between propranolol and Kofarest-LS Syrup 100 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LevosalbutamolLabetalol
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
When Kofarest-LS Syrup 100 ml is used in combination with Labetalol, the therapeutic effectiveness of Kofarest-LS Syrup 100 ml can be decreased which may lead to low treatment outcomes.

How to manage the interaction:
Taking Kofarest-LS Syrup 100 ml with Labetalol may lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
LevosalbutamolCarvedilol
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
Coadministration of Carvedilol and Kofarest-LS Syrup 100 ml may reduce the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Kofarest-LS Syrup 100 ml and Carvedilol, it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
LevosalbutamolSotalol
Severe
How does the drug interact with Kofarest-LS Syrup 100 ml:
Coadministration of Sotalol and Kofarest-LS Syrup 100 ml may decrease the bronchodilatory activities of Kofarest-LS Syrup 100 ml.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Kofarest-LS Syrup 100 ml, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods.
  • Replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.
  • Give your child plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Let your child have fruits rich in water content, such as pears, watermelon, peaches and pineapples.
No
EXPECTORANT AND COUGH PRODUCTS

Kofarest-LS Syrup Substitute

Substitutes safety advice
  • Ascoril LS Expectorant 100 ml

    1.27per tablet
  • Cheston LS Sugar Free Syrup 100 ml

    1.14per tablet
  • Tixylix LS Syrup 100 ml

    1.16per tablet
  • Zerotuss LS Syrup 100 ml

    0.89per tablet
  • Lcf LS Syrup 100 ml

    1.45per tablet
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Not applicable

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Not applicable

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Not applicable

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Not applicable

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Caution

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Caution

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Safe if prescribed

FAQs

Kofarest-LS Syrup is used to treat Cough in children.
Kofarest-LS Syrup contains Levosalbutamol, Ambroxol hydrochloride, and Guaiphenesin. Levosalbutamol relaxes muscles and widens the airways of the lungs. Ambroxol hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thus, it helps to cough out easily. Guaiphenesin increases the volume of fluid in the airways, reduces the stickiness of mucus, and helps to remove it from the airways.
Kofarest-LS Syrup should be used with caution in children with hyperthyroidism (overactive thyroid) as it may worsen the condition. Inform the doctor if your child has hyperthyroidism before using Kofarest-LS Syrup so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while using Kofarest-LS Syrup for your child.
Kofarest-LS Syrup may cause diarrhoea as a common side effect. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to stop using Kofarest-LS Syrup for your child without consulting the doctor as it may worsen the cough or cause recurring symptoms. Therefore, use Kofarest-LS Syrup for as long as your doctor has prescribed it, and if your child experiences any difficulty while using Kofarest-LS Syrup , please consult your doctor.
Kofarest-LS Syrup is generally used for wet or productive cough only. Consult your doctor for more personalized guidance.
No, Kofarest-LS Syrup does not contain any active ingredient to treat pain.
No, you will not get addicted to Kofarest-LS Syrup .
Kofarest-LS Syrup is a combination of three drugs, namely Levosalbutamol (bronchodilator), Ambroxol hydrochloride (mucolytic agent), and Guaiphenesin (expectorant) used to provide relief from cough in children.
Usually, it is safe to use as directed by the physician. Sometimes, Kofarest-LS Syrup may cause common side effects such as nausea, vomiting, indigestion, diarrhea, headache, dry mouth or throat. Most of these side effects of Kofarest-LS Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is recommended not to use it if your child is allergic to any component. Also, inform your doctor about your child's medical history and medications. Your doctor will weigh the benefits over the risks.
Usually, it does not cause dizziness. If you observe any symptoms related to it, please seek medical attention.
Use Kofarest-LS Syrup for children as prescribed by the doctor. The dose may differ from person to person based on medical condition, child's age, and body weight.
INDIA
CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Other Info - KOF0104

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