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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Jan 1, 2025 | 2:49 PM IST
KODEX SYRUP 100ML is used to treat dry cough associated with a common cold or upper respiratory allergies. It contains Chlorpheniramine and Codeine, which works by blocking the action of histamine, a substance responsible for causing allergic reactions. Also, it decreases the urge to cough. In some cases, you may experience certain side effects, such as drowsiness, dry mouth, vomiting, blurred vision, constipation, dizziness, or tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About KODEX SYRUP 100ML

KODEX SYRUP 100ML belongs to a class of medication called ‘cough and cold preparations’ primarily used to treat dry cough associated with a common cold or upper respiratory allergies. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

KODEX SYRUP 100ML is a combination of two drugs: Chlorpheniramine (antihistamine) and Codeine (cough suppressant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Codeine belongs to the class of cough suppressants that blocks the μ-opioid receptor in the brain that produces cough, thereby decreasing the urge to cough.

Take KODEX SYRUP 100ML as prescribed by your doctor. Take KODEX SYRUP 100ML for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain side effects, including drowsiness, dry mouth, vomiting, blurred vision, constipation, dizziness, or tiredness. Most of these side effects of KODEX SYRUP 100ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to KODEX SYRUP 100ML or any other medicines. Drink plenty of fluids while taking KODEX SYRUP 100ML to loosen mucus and protect yourself from being dehydrated or overheated during exercise. In hot weather, as KODEX SYRUP 100ML contains chlorpheniramine, it decreases sweating and increases heatstroke risk. Do not take KODEX SYRUP 100ML if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. KODEX SYRUP 100ML is not recommended for children below 18 years of age. Do not take KODEX SYRUP 100ML if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days, as it may cause life-threatening drug interaction. KODEX SYRUP 100ML is a habit-forming drug, and hence there is a risk of dependence on KODEX SYRUP 100ML. So, before stopping KODEX SYRUP 100ML, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feelings.

Uses of KODEX SYRUP 100ML

Treatment of Dry Cough

Medicinal Benefits

KODEX SYRUP 100ML is a combination of two drugs: Chlorpheniramine and Codeine. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Codeine belongs to the class of narcotic cough suppressants that block the μ-opioid receptor in the brain that produces cough, thereby decreasing the urge to cough. KODEX SYRUP 100ML is used to treat cough associated with a common cold or upper respiratory allergies.

Side Effects of KODEX SYRUP 100ML

  • Dizziness/Drowsiness
  • Mood changes
  • Tiredness/weakness
  • Headache
  • Blurred vision
  • Dry mouth
  • Constipation
  • Coordination problems

Directions for Use

It is available in syrup and tablet forms.Tablet: Your doctor will recommend how often you take this medicine based on your medical condition. Do not crush, chew, or break the tablet.Syrup: Shake the bottle well before use. Check the label for directions and take this medicine on an empty stomach or as prescribed by your doctor with the help of a measuring cup provided with the pack.Do not use this medicine unless prescribed by your doctor. Always take it as your doctor told you. Your doctor will advise you on how often to take this medicine on the basis of your medical condition.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please tell your doctor if you are allergic to KODEX SYRUP 100ML or any other medicines. Do not take KODEX SYRUP 100ML for a prolonged time; $ name contains codeine that may lead to mental or physical dependence on KODEX SYRUP 100ML. Do not take KODEX SYRUP 100ML if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. KODEX SYRUP 100ML is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as a dangerous drug interaction could occur. KODEX SYRUP 100ML should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Drink plenty of fluids while taking KODEX SYRUP 100ML to loosen mucus and protect yourself from being dehydrated or overheated during exercise. In hot weather, as KODEX SYRUP 100ML contains chlorpheniramine, it decreases sweating and increases heatstroke risk. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, kidney, liver, heart or urinary problems, inform your doctor before taking KODEX SYRUP 100ML.

Therapeutic Class

COUGH AND COLD PREPARATIONS

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

Yes

How KODEX SYRUP 100ML Works

KODEX SYRUP 100ML is a combination of two drugs: Chlorpheniramine (antihistamine) and Codeine (cough suppressant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Codeine belongs to the class of cough suppressants that blocks the μ-opioid receptor in the brain that produces cough, thereby decreasing the urge to cough.

What if I have taken an overdose of KODEX SYRUP 100ML

Do not take more than the prescribed dose of KODEX SYRUP 100ML as it may cause overdose. The symptoms of overdose include fast/slow/irregular heartbeat, confusion, cold/clammy skin, seizures (fits), slow/shallow breathing and coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid consumption of alcohol with KODEX SYRUP 100ML as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

KODEX SYRUP 100ML is not recommended for use during pregnancy. KODEX SYRUP 100ML may cause harmful effects on the baby (foetus). Please consult your doctor. So your doctor will weigh the benefits and potential risks before prescribing KODEX SYRUP 100ML for you.

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Breast Feeding

Unsafe

KODEX SYRUP 100ML may be excreted in breast milk and cause harm to the baby. Therefore, KODEX SYRUP 100ML should not be used by breastfeeding mothers without a doctor’s advice.

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Driving

Unsafe

KODEX SYRUP 100ML may cause dizziness, drowsiness, blurred vision, or impaired thinking in some people. Therefore, drive only if you are alert after taking KODEX SYRUP 100ML.

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Liver

Caution

Take KODEX SYRUP 100ML with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take KODEX SYRUP 100ML with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

KODEX SYRUP 100ML is not recommended for children below 18 years of age.

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot ? C, ?G? Block, Bandra-Kurla Complex, Bandra (East), Mumbai ? 400 051, India.
Other Info - KOD0004

Author Details

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FAQs

KODEX SYRUP 100ML is used to treat dry cough associated with a common cold or upper respiratory allergies.
KODEX SYRUP 100ML is a combination of two drugs, namely; Chlorpheniramine and Codeine, which relieves dry cough. Chlorpheniramine Maleate is an antihistaminic that blocks the action of a chemical messenger (histamine), which may trigger a cough due to allergy. Codeine is a cough suppressant. It suppresses cough by reducing the activity of the cough centre in the brain.
Do not take KODEX SYRUP 100ML with 'alprazolam' as co-administration of these two medicines may increase adverse effects such as sedation, respiratory depression, coma, and death. However, please consult a doctor before taking KODEX SYRUP 100ML with other medicines.
KODEX SYRUP 100ML is excreted in breast milk and may cause drowsiness, breathing problems, or death in a nursing baby. Therefore, if breastfeeding, please inform your doctor before taking KODEX SYRUP 100ML. Your doctor will weigh the benefits and potential risks before prescribing them.
KODEX SYRUP 100ML is not recommended for children below 18 years of age as a misuse of KODEX SYRUP 100ML in children may lead to serious adverse effects. Codeine in KODEX SYRUP 100ML may cause life-threatening respiratory depression and death in children who recently had surgery to remove the tonsils or adenoids.
KODEX SYRUP 100ML may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. KODEX SYRUP 100ML contains Chlorpheniramine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
KODEX SYRUP 100ML is unsafe to use in pregnancy. KODEX SYRUP 100ML contains codeine, If you use KODEX SYRUP 100ML while pregnant, your baby could become dependent on codeine. This can cause life-threatening withdrawal symptoms in the baby after it is born.
Yes, codeine in KODEX SYRUP 100ML may cause mental or physical dependence if used for prolonged periods. Therefore, take KODEX SYRUP 100ML only in dose and duration as advised by your doctor.
You are not recommended to stop taking KODEX SYRUP 100ML even if you feel better, as you may experience withdrawal symptoms such as restlessness, watery eyes, a runny nose, nausea, sweating, and muscle aches. To avoid withdrawal symptoms, your doctor may gradually reduce your dose. The risk of withdrawal is higher if you've been using the medication for a long period (more than a few weeks) or at high doses. If you experience withdrawal symptoms or any difficulty while taking KODEX SYRUP 100ML, please consult your doctor.
Yes, KODEX SYRUP 100ML may make you drowsy or sleepy as it is one of its common side effects. However, please consult a doctor if it persists for longer durations.
Yes, there are serious side effects associated with the use of KODEX SYRUP 100ML such as noisy breathing, shallow breathing, breathing that stops during sleep, confusion, severe drowsiness, light-headed feeling, severe constipation or adrenal gland problems (nausea, vomiting, loss of appetite, feeling very dizzy, weak or tired). Stop using KODEX SYRUP 100ML, and consult a doctor if you have any of these symptoms.
No, higher than the recommended dose of KODEX SYRUP 100ML will not be more effective, instead it can lead to increased side effects. Therefore, do not exceed the recommended dose. If symptoms like confusion, seizures, cold/clammy skin, or irregular heartbeat occur or worsen, please consult your doctor.
Yes, the use of KODEX SYRUP 100ML can cause constipation. It is a temporary side effect and does not require any medical treatment. Please, contact a physician if this persists or worsens.
Avoid alcohol while using KODEX SYRUP 100ML, as it can increase drowsiness, slow your breathing, and other risks. However, if you have any concerns regarding this, please discuss with your doctor.
Store KODEX SYRUP 100ML at a temperature below 25°C in a cool and dry place as advised on label. Protect from light and moisture. Keep it out of reach of children. KODEX SYRUP 100ML should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.

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