KLOTIN INJECTION belongs to the class of medications called ‘anti-fibrinolytic drugs. It is mainly used to treat abnormal bleeding in various conditions such as menorrhagia (heavy bleeding in periods), epistaxis (nose bleeds), cervical surgery (conization of the cervix), post-prostatectomy (prostate surgery), post-cystectomy (bladder surgery), traumatic hyphaema (bleeding inside the eye), before tooth removal (dental extraction) in hemophiliacs (people who bleed more easily than normal) and a hereditary disease called angioneurotic oedema (HANO).

KLOTIN INJECTION contains an anti-fibrinolytic drug, tranexamic acid. Tranexamic acid helps the body's natural blood clotting system by reducing fibrin breakdown, which inhibits fibrinolysis, a process that limits the development of blood clots. As a result, KLOTIN INJECTION contributes to the prevention of excessive bleeding.

KLOTIN INJECTION is a parenteral form. It will be administered by the healthcare professional; do not self-administer. KLOTIN INJECTION may cause side effects such as feeling sick (nausea), diarrhoea, vomiting, itchy skin, and pain at the injection site. These side effects usually disappear with time. However, consult your doctor immediately if these side effects persist or if you develop any other serious side effects, such as vision problems while using KLOTIN INJECTION.

If you are allergic to KLOTIN INJECTION or any other medicines, please inform your doctor. Inform your doctor if you have pre-existing or a history of kidney disease, disseminated intravascular coagulation (a disease where blood clots form throughout your body), thrombosis (formation of blood clots in the blood vessels) or seizures (fits), as this medicine is not recommended in such cases. Also, inform your doctor before receiving this injection if you are using any birth control pills or fibrinolytic agents (medicines that dissolve blood clots) or if you are pregnant, planning pregnancy or breastfeeding.

KLOTIN INJECTION contains tranexamic acid, which is an anti-fibrinolytic medication. Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, and this stops fibrinolysis, a process that stops blood clot formation. Thus KLOTIN INJECTION helps to prevent excessive bleeding.

• Nausea
• Diarrhoea
• Itchy skin
• Pain at the injection site
• Injection site reactions
• Vomiting

Before administering KLOTIN INJECTION, inform your doctor if you notice blood in your urine (except during periods), or have a history of uncontrollable bleeding, disseminated intravascular coagulation (DIC) (a disease where blood clots form throughout your body), irregular periods and kidney disease. Also, inform your doctor if you or your family has a history of thrombosis (formation of blood clots in the blood vessels). Let your doctor know if you are taking medicine to treat a hereditary disease called angioneurotic oedema (HANO) every day for a long time. Your doctor may advise regular eye tests and blood tests to check your vision problems and also liver/kidney functioning. Inform your doctor if you are using birth control pills, including the patch, vaginal ring, and an intrauterine device (IUD), as there is a risk of deep vein thrombosis (a condition in which a blood clot is formed in the deeper vein, mostly the legs). Inform your doctor if you are using fibrinolytic agents (drugs that break blood clots) such as streptokinase, as they may stop the effect of KLOTIN INJECTION. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

Drug-drug interactions: KLOTIN INJECTION may interact with fibrinolytic drugs (streptokinase, urokinase, reteplase, alteplase, and tenecteplase, etc.), an antipsychotic drug (chlorpromazine), and a drug used to treat blood cancer (tretinoin) and progestins (levonorgestrel).

Drug-food interactions: No interactions found.

Drug-disease interactions: KLOTIN INJECTION interacts with various disease conditions, including colour vision defect, active intravascular clotting, intracranial haemorrhage, seizures (fits) and renal dysfunction.

• CHLORPROMAZINE
• TRETINOIN
• STREPTOKINASE
• UROKINASE
• LEVONORGESTREL

• Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.
• Stay hydrated; drink plenty of water.
• Cut down on sugars, salts, spicy food, coffee, and alcohol.
• A heating pad can help ease the pain by placing it on the belly or lower back.
• Exercise can help ease the pain of menstrual cramps.
• Avoid stress by performing meditation or yoga.
• Massage your lower back or abdomen to relieve the pain.
• Take proper rest.

Menorrhagia: It is a condition characterized by heavy or prolonged bleeding during menstrual periods which last for more than seven days

Epistaxis: Bleeding from the nose when the blood vessels of the nose lining burst. This can occur due to dryness or nose injury.

Post-operative bleeding: It is bleeding after surgery due to the blood vessel rupture. Some people may experience mild to severe bleeding due to cuts made during surgery.

Traumatic hyphema: It is a condition characterized by the presence of blood in the anterior chamber of the eye due to a blunt injury. This condition may also result in vision loss.

Hereditary angioneurotic oedema (HANO): Hereditary angioneurotic oedema is a hereditary disease that causes recurrent painless swelling under the skin.