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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST

Kivadase Tablet is used to relieve pain and inflammation associated with various medical conditions, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. It consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

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About Kivadase Tablet

Kivadase Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 

Kivadase Tablet consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Kivadase Tablet should be taken as prescribed by your doctor.  Sometimes it may cause certain common side effects such as nausea, vomiting, stomach pain, loss of appetite, indigestion, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Kivadase Tablet may cause drowsiness and dizziness, so drive with caution. Kivadase Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Kivadase Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions. It is advised not to take more than the prescribed dose of medicine and for a longer period. 

Uses of Kivadase Tablet

Treatment of Pain and inflammation associated with musculoskeletal and joint disorders

Medicinal Benefits

Kivadase Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol, and Trypsin chymotrypsin. Kivadase Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) and Paracetamol is an analgesic. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin is a combination of enzymes that breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation by increasing the blood supply at the affected area.

Side Effects of Kivadase Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Indigestion
  • Loss of appetite
  • Heartburn

Directions for Use

Take Kivadase Tablet with food to prevent stomach upset. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Avoid taking Kivadase Tablet if you are allergic to any of its contents; if you have/had severe heart problems, active or recurring peptic ulcer, gastrointestinal perforation, bleeding problems, inflammation of intestines, or severe liver or kidney impairment. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, a habit of smoking, or liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Kivadase Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. This medicine is not recommended for use in children as safety is not established. It is advised not to take more than the prescribed dose of Kivadase Tablet for a prolonged period.

Therapeutic Class

ANALGESICS

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

Habit Forming

No

What if I have taken an overdose of Kivadase Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Kivadase Tablet may include abdominal pain, bloody, black, or tarry stools, coma and death, drowsiness, liver problems, loss of consciousness, nausea, seizures, slow, shallow, or irregular breathing, stomach pain, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Kivadase Tablet as it may increase drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Inform your doctor if you are pregnant or planning pregnancy before taking Kivadase Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding before taking Kivadase Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Kivadase Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have liver problems. Dose adjustment may be needed. Kivadase Tablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Please consult your doctor if you have kidney impairment. Dose adjustment may be needed. Kivadase Tablet is not recommended for patients with severe renal impairment.

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Children

Unsafe

Kivadase Tablet is not recommended for children as safety and effectiveness have not been established.

Manufacturer/Marketer address

Wz-583 Third Floor Rishi Nagar Delhi-34, Delhi, Delhi, India, 110034
Other Info - KI34509

FAQs

Kivadase Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain.
Kivadase Tablet contains Diclofenac, Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.
Do not take any other medicines for pain relief, such as NSAIDs along with Kivadase Tablet, unless prescribed by a doctor, as it might increase the risk of side effects.
Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Kivadase Tablet might cause serious liver damage or allergic reactions like rash, difficulty breathing, and swelling of the face, throat, and mouth. Therefore, Kivadase Tablet should not be taken for longer durations unless prescribed by the doctor.

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