Kineret 100 mg Injection 0.67 ml

Kineret 100 mg Injection 0.67 ml belongs to the group of immunosuppressive agents used in the treatment of rheumatoid arthritis, Still’s disease, various periodic fever syndromes, neonatal-onset multisystem inflammatory disease (NOMID) and COVID-19. Rheumatoid arthritis is a chronic inflammatory and autoimmune disorder of the joints. Still’s disease is also an inflammatory type of arthritis affecting the joints. Periodic fever syndromes are autoimmune inflammatory syndromes characterised by recurrent bouts of fever and swelling. 

Kineret 100 mg Injection 0.67 ml contains Anakinra, an interleukin-1 receptor antagonist which works by blocking the action of interleukin, a protein that causes inflammation. It shields the body from the harmful effects of proteins called cytokines. Thereby, Kineret 100 mg Injection 0.67 ml helps treat the signs and symptoms of rheumatoid arthritis, Still's disease, periodic fever syndrome, and COVID-19.

Kineret 100 mg Injection 0.67 ml will be administered by a qualified healthcare professional or you may self-administer the injection if you have been properly trained by your doctor or nurse. In some cases, Kineret 100 mg Injection 0.67 ml may cause certain common side effects such as headache, increased blood cholesterol levels, redness, bruising, swelling, or itching at the injection site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components or E. coli as Kineret 100 mg Injection 0.67 ml is produced using E. coli. Keep your doctor informed if you suffer from HIV, asthma, cancer, liver disease, kidney problems, heart disease, epilepsy or a disease of the veins. Offer a detailed medical and vaccination history. Inform the doctor especially if you are on radiotherapy, tumour necrosis factor (TNF-alpha) inhibiting drugs such as etanercept, blood-thinners, anti-rheumatoid drugs, antiepileptics or antivirals. Consult your doctor if you are pregnant or breastfeeding.

Kineret 100 mg Injection 0.67 ml belongs to the group of immunosuppressive agents used in the treatment of rheumatoid arthritis, Still’s disease, various periodic fever syndromes, neonatal-onset multisystem inflammatory disease (NOMID), and COVID-19. Kineret 100 mg Injection 0.67 ml works by shielding the body from the harmful effects of an increased level of proteins called cytokines. Cytokines are body proteins that monitor and regulate the normal functioning of cells. An increase in the level of cytokines (interleukin-1) leads to inflammation and swelling. In normal circumstances, an innate protein regulates the abnormal rise of interleukin-1 and blocks its adverse effects. However, in disease states, this function is compromised. Kineret 100 mg Injection 0.67 ml works by mimicking the body’s natural interleukin-1-blocking protein and screening the harmful effects of the increased interleukin-1.

• Redness, itching, bruising, or swelling at the injection site
• Headache
• Increased blood cholesterol levels

It is advisable to inform the doctor if you are allergic to any of its components or E. coli as Kineret 100 mg Injection 0.67 ml is produced using E. coli. Inform your doctor if you suffer from HIV, asthma, cancer, liver disease, kidney problems, heart disease, low blood cell count, epilepsy, disease of the veins, if you are on radiotherapy, tumour necrosis factor (TNF-alpha) inhibiting drugs such as etanercept, blood-thinners, anti-rheumatoid drugs and antiepileptics. Keep your doctor informed if you have recently had any surgery. Offer a detailed medical and vaccination history. Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding.

Drug-Drug Interactions: Kineret 100 mg Injection 0.67 ml may interact with antiepileptic (phenytoin), anti-TNF (etanercept), anticoagulants (warfarin). 

Drug-Food Interactions: Kineret 100 mg Injection 0.67 ml may interact with alcohol.

Drug-Disease Interactions: Kineret 100 mg Injection 0.67 ml should be used with caution in patients with a known hypersensitivity disorder, HIV, asthma, cancer, liver disease, kidney problems, heart disease, epilepsy or a disease of the veins.

• ETANERCEPT
• PHENYTOIN
• WARFARIN

• Meditation, music and yoga have been proven very effective in helping with mental health.
• Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.
• Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.
• Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health. 
• Keep yourself at a safe distance from people.
• Always sneeze or cough into your elbow and keep a handkerchief with you.
• Wash your hands with soap and water and keep yourself clean.
• Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.
• Doing weight-bearing exercises such as brisk walking, jogging, tennis or even dance can be very useful in promoting overall bone health. However, do not over-exert yourself if you feel too tired or suffer from severely brittle bones. Muscle training activities such as yoga and Pilates can also be very helpful in maintaining healthy bones.
• Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.
• Spend time under the sun (however with proper sunscreen) for quality intake of Vitamin D. Vitamin D is necessary for the absorption of Calcium, which is the most important component of bones.

• Discuss contraception with your doctor while taking Kineret 100 mg Injection 0.67 ml.
• You may self-inject once you have been trained properly. Make sure you get all your questions and queries cleared with your healthcare professional.
• In case you miss a dose of Kineret 100 mg Injection 0.67 ml, contact your doctor to find out when to take the next dose.
• Use Kineret 100 mg Injection 0.67 ml with caution in the elderly as they’re more prone to infections.
• Live vaccinations should not be taken along with Kineret 100 mg Injection 0.67 ml. Discuss with the doctor if you are due to take any vaccines.

Rheumatoid Arthritis: Rheumatoid arthritis is an autoimmune inflammatory disorder of the joints. Autoimmunity is when the body recognises its own cells as foreign and tends to attack them. Rheumatoid arthritis is often seen in conjunction with other autoimmune diseases such as hypothyroidism, inflammatory bowel disease (IBD), vitiligo, lupus etc. Symptoms include stiffness, swelling and weakness at the joints, lumps and redness on the skin, compromised movements, bone erosion and joint deformity.

Still’s Disease: Still’s disease is a form of inflammation and arthritis that causes joint pain, fever and rash. It commonly affects the joints of the wrists.

Coronavirus Disease: Coronavirus disease is an infection caused by the SARS-CoV-2 virus. It can range from a mild cold, cough and fever to full-blown pneumonia. Drop-in oxygen saturations and breathlessness may also occur.