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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Keytruda 100 mg Injection 4 ml is an anti-cancer medicine used in the treatment of various types of cancers in both adult and paediatric populations. It contains Pembrolizumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the action of a programmed death receptor-1 (PD-1), thereby stopping the abnormal growth of cancer cells. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

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Whats That

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Composition :

PEMBROLIZUMAB-100MG

Manufacturer/Marketer :

Msd Pharmaceutical Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Keytruda 100 mg Injection 4 ml

Keytruda 100 mg Injection 4 ml is an anti-cancer medicine used in the treatment of various types of cancers in both adult and paediatric populations. Cancer is a disease caused due to the abnormal growth of cells that divide uncontrollably. This medicine is used in treating advanced renal cell carcinoma, hepatocellular carcinoma, colorectal cancer, non-small cell lung cancer, metastatic melanoma, small cell lung cancer, gastric cancer, classical Hodgkin’s disease, urothelial carcinoma, cervical cancer, primary mediastinal large B-cell lymphoma, endometrial cancer, microsatellite instability-high cancer, and head and neck cancer.

Keytruda 100 mg Injection 4 ml contains Pembrolizumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the action of a programmed death receptor-1 (PD-1) and thereby stops the abnormal growth of cancer cells.

Keytruda 100 mg Injection 4 ml may cause certain side effects such as diarrhoea, nausea, vomiting, tiredness, itching, rash, headache, fever, cough, shortness of breath, muscle/joint pain, loss of appetite and injection site reactions. Inform your doctor if any of these side effects persist for a longer duration. Keytruda 100 mg Injection 4 ml will be administered by an oncologist. Avoid self-administration.

Avoid taking Keytruda 100 mg Injection 4 ml if you are allergic to it or any other components of it. Before taking Keytruda 100 mg Injection 4 ml, inform your doctor if you have/had liver or kidney disease, autoimmune disorders such as ulcerative colitis, Crohn’s disease, any history of organ transplants, received a stem cell transplant that uses donor stem cells (allogeneic), undergone radiation treatment to the chest or any other medical conditions. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

Uses of Keytruda 100 mg Injection 4 ml

Treatment of Renal Cell Carcinoma, Hepatocellular carcinoma, Metastatic Melanoma, non-small cell lung cancer, Malignant pleural mesothelioma, Stomach Cancer, Squamous cell carcinoma of the head and neck, Cervical cancer, and Urothelial carcinoma

Directions for Use

Keytruda 100 mg Injection 4 ml will be administered by a trained oncologist in the hospital setting. Hence, do not self-administer. Your doctor will decide the dose and duration of the medicine based on the severity and type of cancer.

Medicinal Benefits

Keytruda 100 mg Injection 4 ml contains Pembrolizumab, which is used in the treatment different types of cancers. It works by inhibiting the action of a programmed death receptor-1 (PD-1) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

How Keytruda 100 mg Injection 4 ml Works

Keytruda 100 mg Injection 4 ml contains Pembrolizumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the action of a programmed death receptor-1 (PD-1) and thereby stops the abnormal growth of cancer cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Keytruda 100 mg Injection 4 ml

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Tiredness
  • Dizziness
  • Weakness
  • Pain in muscles/joints/bones
  • Cough
  • Headache
  • Fever
  • Itching
  • Rash
  • Back pain
  • Shortness of breath
  • Injection site reactions

What if I have taken an overdose of Keytruda 100 mg Injection 4 ml

As Keytruda 100 mg Injection 4 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

To treat your condition effectually, continue taking Keytruda 100 mg Injection 4 ml for the period that your doctor has prescribed. Keytruda 100 mg Injection 4 ml may cause severe immune-mediated adverse reactions (IMAR) such as immune-mediated colitis, hepatitis (hepatotoxicity), nephritis, endocrinopathies (such as adrenal insufficiency, diabetes, thyroid disorders), pneumonitis, and dermatologic reactions (such as Stevens-Johnson syndrome, epidermal necrolysis). It may also cause infusion-related reactions in some patients. Therefore, caution should be exercised if you have/had liver or kidney disease, any history of organ transplant, received a stem cell transplant that uses donor stem cells (allogeneic), undergone radiation treatment to the chest and autoimmune disorders such as ulcerative colitis, or Crohn’s disease while receiving Keytruda 100 mg Injection 4 ml. Discontinue the treatment if any severe infusion reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children below 2 years of age as the safety and efficacy are not established.

Drug-Drug Interactions

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PembrolizumabThalidomide
Severe
PembrolizumabBetamethasone
Severe

Drug-Drug Interactions

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PembrolizumabThalidomide
Severe
How does the drug interact with Keytruda 100 mg Injection 4 ml:
Taking Keytruda 100 mg Injection 4 ml with thalidomide may increase the risk of serious side effects.

How to manage the interaction:
Although taking thalidomide and Keytruda 100 mg Injection 4 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
PembrolizumabBetamethasone
Severe
How does the drug interact with Keytruda 100 mg Injection 4 ml:
Taking Keytruda 100 mg Injection 4 ml with betamethasone may decrease the effects of Keytruda 100 mg Injection 4 ml, which may make the medication less effective.

How to manage the interaction:
Although there is a possibility of interaction, it can be taken if prescribed by doctor. Do not stop using any medications without consulting a doctor.
PembrolizumabPomalidomide
Severe
How does the drug interact with Keytruda 100 mg Injection 4 ml:
Taking Keytruda 100 mg Injection 4 ml with Pomalidomide together may increase the risk of serious side effects.

How to manage the interaction:
Taking Keytruda 100 mg Injection 4 ml with Pomalidomide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
PembrolizumabLenalidomide
Severe
How does the drug interact with Keytruda 100 mg Injection 4 ml:
Using lenalidomide and Keytruda 100 mg Injection 4 ml together can increase the risk of adverse effects.

How to manage the interaction:
Taking Lenalidomide with Keytruda 100 mg Injection 4 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
PembrolizumabThalidomide
Severe
How does the drug interact with Keytruda 100 mg Injection 4 ml:
Taking Keytruda 100 mg Injection 4 ml with thalidomide may increase the risk of serious side effects.

How to manage the interaction:
Although taking thalidomide and Keytruda 100 mg Injection 4 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any dizziness, blurred vision, or drowsiness consult your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Consult your doctor

It is unknown whether Keytruda 100 mg Injection 4 ml interacts with alcohol. Consult your doctor.

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Pregnancy

Unsafe

Keytruda 100 mg Injection 4 ml is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Keytruda 100 mg Injection 4 ml. You should not become pregnant while you are taking Keytruda 100 mg Injection 4 ml for at least 4 months from the last dose of Keytruda 100 mg Injection 4 ml. Using effective birth control methods while on treatment is suggested.

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Breast Feeding

Unsafe

Keytruda 100 mg Injection 4 ml should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine and at least for 4 months from the last dose of medicine.

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Driving

Caution

Keytruda 100 mg Injection 4 ml will be administered in the hospital setting. Driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before receiving this medicine. Hence, this medicine should be taken cautiously in patients with moderate liver impairment. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Keytruda 100 mg Injection 4 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Keytruda 100 mg Injection 4 ml is safe for use in children above two years of age when recommended by the physician. It will be administered only if the benefits outweigh risks.

FAQs

Keytruda 100 mg Injection 4 ml is used to treat Renal Cell Carcinoma, Hepatocellular carcinoma, Metastatic Melanoma, non-small cell lung cancer, Malignant pleural mesothelioma, Stomach Cancer, Squamous cell carcinoma of the head and neck, Cervical cancer, and Urothelial carcinoma.

Keytruda 100 mg Injection 4 ml contains Pembrolizumab, which works by inhibiting the action of a PD-1 that causes the multiplication of cancerous cells.

Country of origin

India

Manufacturer/Marketer address

Platina, 8Th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Other Info - KEY0037

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