Ketotram Tablet belongs to the group of painkillers and analgesics used short-term to relieve moderate to severe pain. Pain is a sensation that occurs in response to external injury, stress, infection and travels as an impulse through body cells, producing an unpleasant feeling and alerting the body to act.

Ketotram Tablet contains Ketorolac and Tramadol. Ketotram Tablet works by reducing the production of inflammatory substances (prostaglandins) and thus, relieves the body of swelling and subsequent pain. Ketotram Tablet also blocks pain-producing nerve transmitters, thereby providing pain relief. 

Take Ketotram Tablet as prescribed. Ketotram Tablet may cause certain common side effects such as stomach ache, nausea, vomiting, gas, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of Ketotram Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Ketotram Tablet may cause dizziness, so drive only if you are alert. Avoid taking alcohol with Ketotram Tablet as it might lead to increased dizziness.

Ketotram Tablet is an analgesic that is used as a painkiller for short-term management of moderate to severe pain. Ketotram Tablet contains Ketorolac and Tramadol. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing the levels of inflammatory substances called prostaglandins. Prostaglandins are produced at the site of injury and cause inflammation and pain. Tramadol blocks the cellular reuptake of neurotransmitters (sensation-producing substances travelling through nerves) serotonin and noradrenaline, omitting pain impulses at the spinal level. Thus, Ketotram Tablet helps relieve pain.

• Nausea
• Stomach ache
• Gas
• Diarrhoea
• Constipation
• Fatigue
• Dry mouth
• Dizziness

Ketotram Tablet should not be used in case of any known allergy to either of the components or to NSAID’s/opioids in general. Ketotram Tablet is not recommended for use in case of high risk or previous history of peptic ulcer disease, bleeding disorders, heart failure, asthma, IBD or if you have had any kind of stroke (even transient ischaemic stroke). Ketotram Tablet should be used with caution in patients with a known history of substance abuse (individual or within the family), diabetes mellitus, epilepsy, kidney disease, liver disease, arterial or thrombotic disorders, cardiovascular health disorders, mental health issues, asthma, emphysema, pancreatitis, gallbladder disease, bleeding disorders, peptic ulcers, IBD/IBS, enlarged prostate, rheumatoid arthritis, dry eye syndrome, hypertension, obesity, anaemia, nasal polyps (overgrowth in the nose), stroke and any disease-causing swelling in the feet and hands. Consult your doctor before using Ketotram Tablet during pregnancy or breastfeeding as it is not recommended for use in these states. 

Drug-Drug Interactions: Ketotram Tablet may interact with other pain-killers (pentazocin, pentoxifylline, nalbuphine, butorphanol, anti-addiction drug (naltrexone), antihypertensives (captopril, lisinopril, losartan), diuretics (furosemide), mood stabiliser (lithium), DMARD (methotrexate), steroids (prednisolone), blood-thinners (clopidogrel, warfarin, enoxaparin), anti-gout drug (probenecid), anti-epileptic drugs (phenytoin, carbamazepine), psychoactive drugs (fluoxetine, alprazolam), anti-depressants (SSRI’s like citalopram, escitalopram), MAOI’s (selegiline, phenelzine, linezolid, methylene blue, moclobemide, procarbazine), heart medication (quinidine), anti-HIV drug (ritonavir), antifungals (itraconazole, ketoconazole), antibiotics (erythromycin).

Drug-Food Interactions: Ketotram Tablet may interact with high-fat foods and alcohol.

Drug-Disease Interactions: Ketotram Tablet should be used with caution in patients with a known history of substance abuse (individual or within the family), hypersensitivity disorder, diabetes mellitus, epilepsy, kidney disease, liver disease, arterial or thrombotic disorders, cardiovascular health disorders, mental health issues, asthma, emphysema, pancreatitis, gallbladder disease, bleeding disorders, peptic ulcers, IBD/IBS, enlarged prostate, rheumatoid arthritis, dry eye syndrome, hypertension, obesity, anaemia, nasal polyps (overgrowth in the nose), stroke and any disease causing a swelling in the feet and hands.

• PENTAZOCIN
• PENTOXIFYLLINE
• NALBUPHINE
• BUTORPHANOL
• NALTREXONE
• CAPTOPRIL
• LISINOPRIL
• LOSARTAN
• FUROSEMIDE
• LITHIUM
• METHOTREXATE
• PREDNISOLONE
• CLOPIDOGREL
• WARFARIN
• ENOXAPARIN
• PROBENECID
• PHENYTOIN
• CARBAMAZEPINE
• FLUOXETINE
• ALPRAZOLAM
• CITALOPRAM
• ESCITALOPRAM
• SELEGILINE
• PHENELZINE
• LINEZOLID
• METHYLENE BLUE
• MOCLOBEMIDE
• PROCARBAZINE
• QUINIDINE
• RITONAVIR
• ITRACONAZOLE
• KETOCONAZOLE
• ERYTHROMYCIN

• Stay hydrated by drinking plenty of water.
• Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. Limit your intake of sweets and sugars as these can worsen inflammation. 
• Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
• Try meditation and deep breathing to reduce overall stress and pain. 
• Stop smoking as smoking is known to worsen pain conditions. 
• Engage in mild physical exercise daily and keep your body active. 

• In case you miss a dose of Ketotram Tablet , skip it and resume when it is time for the second dose only. Do not ever take a double dose.
• It is very difficult to overdose on Ketotram Tablet however, if you accidentally take extra doses of Ketotram Tablet , please inform your doctor or go to a hospital immediately. Some of the symptoms of an overdose can be blurred vision, shortness of breath, difficulty in speaking, severe headache, unusual tiredness, fainting and or ringing in the ears. 
• Avoid taking antacids within 2-3 hours of Ketotram Tablet .

Pain: Pain is a sensation that occurs in response to external injury, stress, infection and travels as an impulse through body cells, producing an unpleasant feeling and alerting the body to act. Pain relief in pharmacological terms is called analgesia. Various neurotransmitters and their equilibrium are instrumental in producing pain sensation.