Kerendia 20 mg Tablet is used to treat patients with chronic renal damage caused by type 2 diabetes. Kerendia 20 mg Tablet also lowered the occurrence of new-onset heart failure considerably. Chronic renal disease is defined by a gradual kidney function decline over time. Type 2 diabetes occurs when your body cannot maintain normal blood sugar levels.

Kerendia 20 mg Tablet contains the active substance finerenone. It works by blocking the action of certain hormones (mineralocorticoids) that can damage your kidneys and heart.

To treat your condition effectually, continue using Kerendia 20 mg Tablet for as long as your doctor has prescribed it. Kerendia 20 mg Tablet may cause high potassium level (hyperkalaemia), weakness or tiredness, feeling sick (nausea), numbness in the hands and lips, decreased pulse rate, low sodium level (hyponatraemia), tiredness, headache, confusion, muscle weakness, spasms or cramps and high uric acid level (hyperuricaemia) in some cases. Most of these side effects do not necessitate medical attention and will resolve gradually over time. If you are experiencing these side effects regularly, consult your doctor.

If you are allergic to any components in this composition, do not take Kerendia 20 mg Tablet ; if in doubt, check with a healthcare expert. You should not use this medication while pregnant unless your doctor says it is absolutely necessary. You should not breastfeed if you are on this medication; it might harm your child. Kerendia 20 mg Tablet is not recommended for children younger than 18 years old. Do not stop taking Kerendia 20 mg Tablet on your own unless your doctor advises you to. Your doctor may make this decision after checking your blood. Inform your doctor if you have hyperkalemia (high potassium level), severe renal illness, liver illness, heart failure, or Addison's disease (when your body does not generate enough of the hormones 'cortisol' and 'aldosterone').

Kerendia 20 mg Tablet contains the active ingredient finerenone. It belongs to a class of drugs known as non-steroidal mineralocorticoid receptor (MR) antagonists. It is indicated to reduce the risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalisation for heart failure in adult patients with chronic kidney disease associated with type 2 diabetes. Kerendia 20 mg Tablet also lowered the occurrence of new-onset heart failure considerably. It acts by inhibiting the function of specific hormones (mineralocorticoids) that might cause kidney and cardiac damage.

• High potassium level (hyperkalaemia)
• Weakness or tiredness
• Feeling sick (nausea)
• Numbness in the hands and lips
• Muscle cramps
• Decreased pulse rate
• Low sodium level (hyponatraemia)
• Tiredness
• Headache
• Confusion
• Muscle weakness, spasms or cramps
• Decrease in how well the kidneys filter blood (glomerular filtration rate decreased)
• High uric acid level (hyperuricaemia)

Before taking Kerendia 20 mg Tablet , inform your doctor about your medical history (heart, liver or kidney impairment) and other medications (especially diuretics, anti-bacterial and potassium salts) you are currently taking to rule out any potential negative effects. If you are allergic to any components in this composition, do not take Kerendia 20 mg Tablet ; if in doubt, check with a healthcare expert. You must not take medicines that belong to the group of ‘strong CYP3A4 inhibitors’ while taking Kerendia 20 mg Tablet . You should not use this medication while pregnant unless your doctor says it is absolutely necessary. You should not breastfeed if you are on this medication; it might harm your child. This medicine should not be given to children or teenagers under the age of 18 because it is not known whether it is safe and effective in this age group. Do not eat grapefruit or drink grapefruit juice as long as you take Kerendia 20 mg Tablet .

Drug-drug interactions: Kerendia 20 mg Tablet may interact with antifungal medications (e.g. itraconazole or ketoconazole), HIV medications (e.g. ritonavir, nelfinavir, or cobicistat) and anti-depression medicines (e.g. nefazodone).

Drug-food interactions: Reduce the consumption of potassium and phosphate in your diet. Do not consume grapefruit or grapefruit juice while taking Kerendia 20 mg Tablet . 

Drug-disease interactions: Kerendia 20 mg Tablet should be used with caution in patients with a high potassium level in the blood, severe renal function loss or failure, liver difficulties, heart failure, or Addison's disease (when your body does not generate enough of the hormones 'cortisol' and 'aldosterone').

• ITRACONAZOLE
• KETOCONAZOLE
• RITONAVIR
• NELFINAVIR
• COBICISTAT
• NEFAZODONE

• A healthy, balanced diet lowers your risk of kidney disease. Keep your blood pressure and cholesterol at a healthy level.
• A well-balanced diet should include plenty of fruits and vegetables.
• Include starchy foods such as potatoes, wholegrain bread, rice, or pasta in your main meal.
• For a protein source, include beans or pulses, fish, eggs, or meat in your daily diet.
• Limit intake of saturated fat, salt, and sugar.
• Limit the amount of potassium or phosphate in your diet.
• Quit smoking. Avoid or limit the consumption of alcohol.

• Do not skip any laboratory appointments, as your doctor will need to regularly check your liver and kidneys and blood and urine samples.

Chronic kidney disease: Chronic kidney disease, also known as chronic kidney failure, is a long-term kidney condition that results in renal failure. Kidneys remove waste and extra fluid from the blood. Renal disease is characterised by a steady decline of kidney function over time. As a result, waste can accumulate to dangerously high levels in the blood, potentially making you sick. Loss of appetite, nausea, vomiting, sleep problems, and swelling of the feet and ankles are the symptoms of renal failure. Treatment focuses mostly on stopping the progression of kidney disease by addressing the underlying cause.