Jotter-AT LS 10/100 Tablet is indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to damaged sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).
 
Jotter-AT LS 10/100 Tablet is a combination of two drugs: Gabapentin (anti-convulsant) and Amitriptyline (tricyclic antidepressant). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain. Amitriptyline works by increasing the serotonin and noradrenaline (natural substances) levels in the brain, thereby preventing the movement of pain signals in the brain. Together, Jotter-AT LS 10/100 Tablet helps in providing relief from neuropathic pain.
 
You are advised to take Jotter-AT LS 10/100 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Jotter-AT LS 10/100 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Please consult your doctor if you have any concerns regarding the usage of Jotter-AT LS 10/100 Tablet in children. Avoid consuming alcohol along with Jotter-AT LS 10/100 Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Jotter-AT LS 10/100 Tablet is a combination of two drugs: Gabapentin and Amitriptyline. Gabapentin belongs to a class of drugs called anti-convulsants, whereas Amitriptyline belongs to tricyclic antidepressants. Jotter-AT LS 10/100 Tablet is used to treat neuropathic pain. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain. Amitriptyline works by increasing the level of chemical messengers such as noradrenaline and serotonin, thereby preventing the movement of pain signals in the brain. Together, Jotter-AT LS 10/100 Tablet helps in providing relief from neuropathic pain.

• Dizziness
• Sleepiness
• Tiredness
• Headache
• Nausea
• Vomiting
• Dry mouth

Do not take Jotter-AT LS 10/100 Tablet if you are allergic to any of its contents; if you recently had a heart attack, if you have heart rhythm problems, severe liver disease or if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14days. Inform your doctor if you have/had heart, kidney or liver problems, nervous system disorders, respiratory disorders, or muscle weakness. Consult your doctor if you are pregnant or breastfeeding. Jotter-AT LS 10/100 Tablet may cause drowsiness, dizziness and blurred vision, so drive only if you are alert. Avoid consuming alcohol along with Jotter-AT LS 10/100 Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions: Jotter-AT LS 10/100 Tablet may interact with hypnotics (zolpidem), antidepressants (duloxetine, escitalopram, sertraline), pain killers (hydrocodone, acetaminophen), anti-histamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), anti-convulsant (pregabalin, topiramate), anti-thyroid (levothyroxine), anti-anxiety (alprazolam), anti-psychotic (quetiapine).

Drug-Food Interactions: Avoid alcohol consumption while taking Jotter-AT LS 10/100 Tablet as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Inform your doctor if you have heart problems, pheochromocytoma (tumour of the adrenal gland), depression, seizures, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, glaucoma, diabetes, thyroid problems, suicidal tendency, haemodialysis, kidney or liver problems.

• ZOLPIDEM
• DULOXETINE
• ESCITALOPRAM
• SERTRALINE
• HYDROCODONE
• ACETAMINOPHEN
• DIPHENHYDRAMINE
• CETIRIZINE
• CYCLOBENZAPRINE
• PREGABALIN
• TOPIRAMATE
• LEVOTHYROXINE
• ALPRAZOLAM
• QUETIAPINE

• Include food rich in vitamin B and D in your diet.

• Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

• Exercising regularly helps in improving overall health and combating pain. 

• Rest well, get plenty of sleep.

• Try taking a warm bath, as it can be soothing.

• Avoid smoking and alcohol consumption.

• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

• Acupuncture can be helpful by stimulating pressure points.

• Using essential oils for massages can help increase circulation.

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).