Joseiz-50 Tablet belongs to the class of anticonvulsants, which is primarily used to treat focal (partial) seizures in adults and children four years of age or older. Focal or partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere.

Joseiz-50 Tablet contains lacosamide, which treats seizures by decreasing disorganized electrical activity in the brain.

In some cases, you may experience certain common side effects of Joseiz-50 Tablet : nausea, vomiting, diarrhoea, headache, confusion, dizziness, uncontrolled movements of the eye, blurred vision, double vision (diplopia), mood disturbances, itching, tremors, fatigue, and trouble walking. Consult your doctor if the side effects persist or worsen over time. Some people may also experience suicidal thoughts. Seek medical attention immediately in such cases.

Do not stop taking Joseiz-50 Tablet even if your condition is controlled, as abrupt stopping may cause the recurrence of the seizures. Before taking Joseiz-50 Tablet , inform your doctor if you are allergic to lacosamide or other ingredients, if you are using other antiepileptics, prescription or non-prescription drugs, nutritional supplements, or herbal products or if you are diagnosed with depression, severe renal impairment, arrhythmias (atrioventricular block, atrial fibrillation, and atrial flutter), severe heart failure, or a heart attack.

Joseiz-50 Tablet is an antiepileptic drug, also called anticonvulsant. It treats focal seizures in adults and children above four years of age.  Joseiz-50 Tablet inactivates the sodium channels across the neuron membranes. This inactivation decreases neuron signals, thereby decreasing the electrical disturbance or abnormal activity in the brain.

• Nausea
• Vomiting
• Diarrhoea
• Dizziness
• Headache
• Drowsiness
• Fatigue
• Blurred vision
• Uncontrollable eye movements
• Impaired coordination
• Uncontrollable movements
• Balance problems
• Pruritus (itching)
• Tremors
• Difficulty walking
• Weakness

Inform your doctor if you use other antiepileptics, prescription or non-prescription drugs, nutritional supplements, or herbal products. Do not take Joseiz-50 Tablet if you are allergic to any of its contents. Inform your doctor before taking Joseiz-50 Tablet if you have or had heart problems, kidney and liver problems, if you have low levels of sodium in blood or if you are taking medicines that could lower the sodium levels in the blood, or if you are using hormonal contraceptives. Do not stop taking Joseiz-50 Tablet without consulting your doctor to avoid precipitating seizures. Avoid intake of Joseiz-50 Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor. Nursing mothers should consult the doctor before using the Joseiz-50 Tablet as it may pass into the breast milk and affect the baby. Joseiz-50 Tablet causes drowsiness and dizziness, so drive only if you are alert. Joseiz-50 Tablet should not be given to children unless prescribed. Avoid consuming alcohol with Joseiz-50 Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Drug-Drug interactions: Joseiz-50 Tablet may interact with HIV medications (e.g. atazanavir, saquinavir), opioid medications (e.g. buprenorphine), anticancer medications (e.g. ceritinib), medicines used to prevent nausea and vomiting caused by cancer chemotherapy (e.g. dolasetron), anaesthetic medications (e.g. ketamine), used to treat multiple sclerosis (e.g. ponesimod, siponimod), medicines used to treat episodes of muscle weakness (e.g. sodium oxybate).

Drug-Food interactions: Avoid consumption of alcohol while taking Joseiz-50 Tablet as it might cause increased dizziness and sleepiness.

Drug-Disease interactions: Joseiz-50 Tablet should be used with caution in patients with depression, renal or hepatic impairment and heart conditions.

• ATAZANAVIR
• SAQUINAVIR
• BUPRENORPHINE
• CERITINIB
• DOLASETRON
• KETAMINE
• PONESIMOD
• SIPONIMOD
• SODIUM OXYBATE

• A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
• Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
• Exercising regularly helps in maintaining weight and improving overall health. 
• Rest well, and get plenty of sleep.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
• Have a seizure response plan, and help those around you know what to do.
• Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
• Understand what triggers seizures are and try reducing or avoiding them.
• Please pay attention to overall health, as it can help reduce seizure activity.
• Install an alarm or emergency device to get assistance during a seizure attack.

Focal or partial-onset seizures are characterized by abnormal electrical activity in only one hemisphere of the brain. Common symptoms of focal seizures are involuntary muscle contractions, followed by relaxation on one side of the body, uncontrolled head or eye movements, a feeling of déjà vu, rapid heart rate, and a tingling sensation on the skin. The symptoms vary in each patient depending on the part of the brain affected.