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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Jonvir-ET Tablet is used to treat HIV infection. It works by inhibiting enzymes which are necessary for the reproduction of the virus. In some cases, this medicine may cause side effects such as headache, dizziness, nausea, insomnia and fatigue. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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About Jonvir-ET Tablet

Jonvir-ET Tablet belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

You should take this medicine exactly as prescribed by the doctor. Jonvir-ET Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.

It is not recommended to take Jonvir-ET Tablet if you are allergic to any contents of it. Before taking Jonvir-ET Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, Hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Jonvir-ET Tablet should not be given to children below 2 years of age. Jonvir-ET Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Jonvir-ET Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Jonvir-ET Tablet

Treatment of HIV infection.

Directions for Use

Swallow Jonvir-ET Tablet as a whole with water. Do not chew, crush or break it. Jonvir-ET Tablet is to be taken empty stomach.

Medicinal Benefits

Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

 

How Jonvir-ET Tablet Works

Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Jonvir-ET Tablet

  • Headache
  • Dizziness
  • Nausea
  • Insomnia (difficulty in sleeping)
  • Weakness
  • Depression
  • Cough
  • Diarrhoea
  • Impaired concentration
  • Abnormal dreams
  • Fatigue
  • Nasal congestion (stuffy nose)
  • Pain

What if I have taken an overdose of Jonvir-ET Tablet

Take Jonvir-ET Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, trouble concentrating, sleepiness, unusual dreams, hallucination, uncontrolled muscle movements or shaking, and difficulty falling or staying asleep. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is not recommended to take Jonvir-ET Tablet if you are allergic to any contents of it. Before taking Jonvir-ET Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Jonvir-ET Tablet should not be given to children below 2 years of age. Jonvir-ET Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Jonvir-ET Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Jonvir-ET Tablet should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis.

Drug-Drug Interactions

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EfavirenzThioridazine
Critical
EfavirenzErgometrine
Critical

Drug-Drug Interactions

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EfavirenzThioridazine
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Jonvir-ET Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jonvir-ET Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Jonvir-ET Tablet:
When Jonvir-ET Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Jonvir-ET Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzRilpivirine
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Rilpivirine with Jonvir-ET Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Rilpivirine with Jonvir-ET Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzBepridil
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Bepridil with Jonvir-ET Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Jonvir-ET Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzCarbamazepine
Critical
How does the drug interact with Jonvir-ET Tablet:
Using carbamazepine together with Jonvir-ET Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Jonvir-ET Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzVoriconazole
Critical
How does the drug interact with Jonvir-ET Tablet:
Coadministration of Voriconazole with Jonvir-ET Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Jonvir-ET Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
EfavirenzLomitapide
Critical
How does the drug interact with Jonvir-ET Tablet:
When Jonvir-ET Tablet is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Jonvir-ET Tablet with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzRanolazine
Critical
How does the drug interact with Jonvir-ET Tablet:
When Jonvir-ET Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Jonvir-ET Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
EfavirenzDienogest
Critical
How does the drug interact with Jonvir-ET Tablet:
When Jonvir-ET Tablet is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Jonvir-ET Tablet with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Jonvir-ET Tablet:
Taking Jonvir-ET Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jonvir-ET Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly. Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Eating a diet high in vegetables, fruits, whole grains, and legumes.
  • Choosing lean, low-fat sources of protein.
  • Limiting sweets, soft drinks, and foods with added sugar.
  • Including proteins, carbohydrates, and a little good fat in all meals and snacks.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Jonvir-ET Tablet Substitute

Substitutes safety advice
  • Trioday Tablet 30's

    94.44per tablet
  • Tenolam E Tablet 30's

    94.44per tablet
  • Forstavir-LE Tablet 30's

    by AYUR

    89.30per tablet
  • T-Lamirenz Tablet

    77.90per tablet
  • Lacavir-ET Tablet

    79.27per tablet
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Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects.

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Pregnancy

Caution

Jonvir-ET Tablet is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this Jonvir-ET Tablet.

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Breast Feeding

Caution

Jonvir-ET Tablet is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

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Driving

Caution

Jonvir-ET Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Jonvir-ET Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Jonvir-ET Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Jonvir-ET Tablet is not recommended for use in children below 2 years. In children above 2 years of age, dose adjustments may be necessary.

FAQs

Jonvir-ET Tablet is used to treat HIV infection.
Jonvir-ET Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Jonvir-ET Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
Jonvir-ET Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.
Jonvir-ET Tablet may cause the weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
Jonvir-ET Tablet should not be stopped suddenly. Inform your doctor before stopping Jonvir-ET Tablet.
Jonvir-ET Tablet should be used with caution in liver diseases, kidney diseases, hypercholesterolemia, CNS disorders and lactic acidosis.

Country of origin

India
Other Info - JO89603

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