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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Jesgab-T Tablet is used for the management of neuropathic pain. It contains Pregabalin and Amitriptyline, which works by increasing the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Thus, helps in relieving nerve pain. It may cause common side effects such as weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Jesgab-T Tablet

Jesgab-T Tablet is a combination medicine indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation.

Jesgab-T Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain. 

You are advised to take Jesgab-T Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Jesgab-T Tablet may cause drowsiness and dizziness, so drive only if you are alert. Jesgab-T Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Jesgab-T Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Jesgab-T Tablet

Treatment of Neuropathic pain

Directions for Use

Take Jesgab-T Tablet with or without food. Swallow Jesgab-T Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Jesgab-T Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain. 

How Jesgab-T Tablet Works

Jesgab-T Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Jesgab-T Tablet

  • Weight gain
  • Dry mouth
  • Blurred vision
  • Dizziness
  • Tiredness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

What if I have taken an overdose of Jesgab-T Tablet

Do not take more than the prescribed dose of Jesgab-T Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Jesgab-T Tablet if you are allergic to any of its contents; if you have taken MAO inhibitors in the last 14days. Inform your doctor before taking Jesgab-T Tablet if you have/had heart problems, bipolar syndrome, severe liver disease or porphyria. Consult your doctor if you are pregnant or breastfeeding. Jesgab-T Tablet may cause drowsiness and dizziness, so drive only if you are alert. Jesgab-T Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Jesgab-T Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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AmitriptylineSaquinavir
Critical
AmitriptylineTranylcypromine
Critical

Drug-Drug Interactions

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AmitriptylineSaquinavir
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Saquinavir may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Saquinavir may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineTranylcypromine
Critical
How does the drug interact with Jesgab-T Tablet:
Taking Tranylcypromine with Jesgab-T Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although using Tranylcypromine and Jesgab-T Tablet together is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Jesgab-T Tablet:
Jesgab-T Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Jesgab-T Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineBepridil
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSafinamide
Critical
How does the drug interact with Jesgab-T Tablet:
Using Jesgab-T Tablet together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineProcarbazine
Critical
How does the drug interact with Jesgab-T Tablet:
Using Jesgab-T Tablet together with Procarbazine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Procarbazine and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineSparfloxacin
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineLinezolid
Critical
How does the drug interact with Jesgab-T Tablet:
Taking Linezolid with Jesgab-T Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linezolid and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineRasagiline
Critical
How does the drug interact with Jesgab-T Tablet:
Using Jesgab-T Tablet together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, and get plenty of sleep.

  • Try taking a warm bath, as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Jesgab-T Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Jesgab-T Tablet; your doctor will decide whether Jesgab-T Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Jesgab-T Tablet may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Jesgab-T Tablet should not be given to children as the safety and efficacy have not been established.

FAQs

Jesgab-T Tablet is used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.Â
Jesgab-T Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Dry mouth could be a side-effect of Jesgab-T Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
To treat your condition effectually, continue taking Jesgab-T Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Jesgab-T Tablet; your doctor will reduce the dose gradually.
Jesgab-T Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.
Jesgab-T Tablet may cause sexual disturbances such as decreased sex drive and problems with erection. Consult your doctor if you have any concerns regarding this.
Jesgab-T Tablet contains Pregabalin and Amitriptyline. Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain.
Jesgab-T Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Helps in the management of neuropathic pain.
To manage weight gain associated with the use of Jesgab-T Tablet, focus on healthy habits such as consuming nutrient-dense foods, limiting your intake, and frequent exercising. Additionally, stay hydrated and get sufficient sleep. Also, seek advice from your doctor regarding weight management.
Jesgab-T Tablet may cause sleepiness or drowsiness as it is a common side effect in some individuals. To ensure your safety, rest for a while after taking Jesgab-T Tablet and avoid driving. In most cases, sleepiness or drowsiness vanishes as your body adjusts to the medication. If the sleepiness or drowsiness worsens or persists, consult your doctor for guidance.
The use of Jesgab-T Tablet may rarely cause turn urine colour to blue or green. If you notice any unusual changes, inform your doctor.
In rare cases, some side effects of Jesgab-T Tablet may become serious in some individuals including severe blurred vision, dizziness, stomach issues like nausea and vomiting, and unusual weight gain. If you experience any of these, seek medical help.
Usually, Jesgab-T Tablet starts working within a few weeks, but it may vary from person to person depending on individual condition, response, and dosage. Always follow your doctor's instructions.
If you forget a dose of Jesgab-T Tablet, take it immediately when you remember. But, if your next dose is nearer, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
If you take too much Jesgab-T Tablet by mistake, please contact your doctor or emergency services immediately. Overdose symptoms may include drowsiness, confusion, and changes in heartbeat.
No, higher than the recommended dose of Jesgab-T Tablet does not provide more effectiveness or additional relief. Instead, it may increase the risk of adverse effects.
When taking Jesgab-T Tablet avoid drinking alcohol, driving if you are feeling dizzy or sleepy, and taking other medications without consulting your doctor. Always follow your doctor's instructions and don't increase the prescribed dose.
See your doctor as per your scheduled follow-up. The frequency of visits varies based on your health needs. If you are having any concerns or unusual symptoms, you can schedule a visit to discuss with your doctor.
Store Jesgab-T Tablet in a cool dry place protected from sunlight and moisture. Keep them out of reach of children and pets. Regularly check the expiry date. To dispose of the medicine place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink.
The common side effects of the Jesgab-T Tablet, which may occur in some individuals are weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Most of these side effects will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects frequently.

Country of origin

India
Other Info - JE33421

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