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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Ivables 5 Tablet is used to treat symptomatic stable angina pectoris and chronic heart failure. It contains Ivabradine, which works by reducing the heart rate by a few beats per minute. In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen. This helps control or reduce the chances of more angina attacks. It may cause side effects such as feeling tired, irregular or rapid feeling heartbeat, headache, dizziness, visual impairment or blurry vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

IVABRADINE-5MG

Manufacturer/Marketer :

Lloyd Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Ivables 5 Tablet

Ivables 5 Tablet is used to treat symptomatic stable angina pectoris and chronic heart failure. In angina, Ivables 5 Tablet  is suggested to adults whose heart rate is over or equal to 70 beats per minute and who cannot take or tolerate heart medicine called beta-blockers. In chronic heart failure, this medicine is suggested with standard therapy for adult patients whose heart rate is over or equal to 75 beats per minute. 

Ivables 5 Tablet contains Ivabradine, which works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen. This helps control or reduce the chances of more angina attacks.

Ivables 5 Tablet should be taken as prescribed by the doctor. Seek medical attention immediately if you notice any sign of an allergic reaction, including hives, swelling of the face and lips, and difficulty breathing. The possible side effects of using Ivables 5 Tablet include feeling tired, irregular or rapid feeling heartbeat, headache, dizziness, visual impairment or blurry vision. Ivables 5 Tablet may increase the brightness of the eyes, especially during the first two months after starting the treatment. These effects will pass with time or after the completion of treatment.

A person dealing with a serious heart condition such as sick sinus syndrome is not allowed to take Ivables 5 Tablet . The usage of Ivables 5 Tablet is not allowed in persons who are allergic to any of its constituents or pregnant or breastfeeding females or children below 18 years. Keep your doctor informed about your health condition and all the medicines you are taking before taking this medicine to rule out any side effects.

Uses of Ivables 5 Tablet

Treatment of Angina, chronic heart failure

Directions for Use

Take Ivables 5 Tablet as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Ivables 5 Tablet is a heart medicine suggested to treat symptomatic stable angina pectoris and chronic heart failure. Ivables 5 Tablet comes under the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers that slow the heart rate by a few beats per minute so that the heart can pump more oxygenated blood according to the needs of the body. Ivables 5 Tablet is responsible for reducing oxygen requirement in conditions where the angina attack may happen. In this way, this medicine controls and reduces the number of angina attacks. Additionally, a high rate could affect the functioning of the heart and may cause serious consequences in patients dealing with chronic heart failure. By reducing the heart rate, this medicine improves the heart's functioning and helps improve chronic heart failure.

How Ivables 5 Tablet Works

Ivables 5 Tablet contains Ivabradine, which works by reducing the heart rate by a few beats per minute.  In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen. This helps control or reduce the chances of more angina attacks.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ivables 5 Tablet

  • Feeling tired
  • Irregular or rapid feeling heartbeat
  • Headache
  • Dizziness
  • Visual impairment or blurry vision

What if I have taken an overdose of Ivables 5 Tablet

Do not take more than the prescribed dose of Ivables 5 Tablet as it may cause overdose. The symptoms of overdose include very slow heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

One should not take Ivables 5 Tablet if they have pre-existing sick sinus syndrome, liver disease, or have very low blood pressure as Ivables 5 Tablet reduces the heart rate so that heart can pump more effectively. Before taking this medicine, a person should tell their doctor about their pre-existing medical conditions and ongoing medications. Using Ivables 5 Tablet is strictly restricted in pregnant women as this medicine may harm an unborn baby. A woman should use effective birth control pills to avoid chances of pregnancy. A person may face serious heart rhythm problems after taking Ivables 5 Tablet , so if a person notices racing heartbeats, very slow heartbeats, severe dizziness, or tiredness, then they must tell their doctor about it on an immediate basis. The usage of Ivables 5 Tablet is not allowed in children below 18 years of age. Tell your doctor if you have lactose intolerance, as this medicine consists of lactose.

Drug-Drug Interactions

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IvabradineImatinib
Critical
IvabradineKetoconazole
Critical

Drug-Drug Interactions

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IvabradineImatinib
Critical
How does the drug interact with Ivables 5 Tablet:
Coadministration of Ivables 5 Tablet with Imatinib can increase the levels of Ivables 5 Tablet in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Ivables 5 Tablet with Bosutinib together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineKetoconazole
Critical
How does the drug interact with Ivables 5 Tablet:
Coadministration of Ivables 5 Tablet with Ketoconazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ivables 5 Tablet with Ketoconazole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradineCeritinib
Critical
How does the drug interact with Ivables 5 Tablet:
Coadministration of Ivables 5 Tablet with ceritinib can increase the levels and effects of Ivables 5 Tablet.

How to manage the interaction:
Taking Ivables 5 Tablet with Ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
IvabradinePosaconazole
Critical
How does the drug interact with Ivables 5 Tablet:
Using Ivables 5 Tablet together with posaconazole may significantly increase the blood levels and effects of Ivables 5 Tablet.

How to manage the interaction:
Taking Ivables 5 Tablet with Posaconazole together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineVoriconazole
Critical
How does the drug interact with Ivables 5 Tablet:
Using Ivables 5 Tablet together with voriconazole may significantly increase the blood levels and effects of Ivables 5 Tablet.

How to manage the interaction:
Taking Ivables 5 Tablet with Voriconazole together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
IvabradineClofazimine
Severe
How does the drug interact with Ivables 5 Tablet:
Co-administration of Ivables 5 Tablet with clofazimine can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking Ivables 5 Tablet with Clofazimine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineClotrimazole
Severe
How does the drug interact with Ivables 5 Tablet:
Coadministration of Ivables 5 Tablet with clotrimazole may increase the blood levels of Ivables 5 Tablet, which may result in an excessive slowing of the heart rate.

How to manage the interaction:
Although taking Clotrimazole with Ivables 5 Tablet may result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience dizziness, fatigue, or low blood pressure. irregular heartbeat, or shortness of breath, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
IvabradineFosphenytoin
Severe
How does the drug interact with Ivables 5 Tablet:
Coadministration of Ivables 5 Tablet with Fosphenytoin can induce the metabolism and decrease the levels of Ivables 5 Tablet in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Ivables 5 Tablet with Fosphenytoin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IvabradineRanolazine
Severe
How does the drug interact with Ivables 5 Tablet:
Co-administration of Ivables 5 Tablet with Ranolazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ivables 5 Tablet with Ranolazine together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
IvabradineTrazodone
Severe
How does the drug interact with Ivables 5 Tablet:
Coadministration of Ivables 5 Tablet with Trazodone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ivables 5 Tablet with Trazodone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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IVABRADINE-5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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IVABRADINE-5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
grapefruit juice can significantly increase the blood levels and effects of Ivables 5 Tablet, which may result in excessive slowing of heart rate or other conduction disturbances. Avoid or limit the consumption of grapefruit or grapefruit juice while taking Ivables 5 Tablet therapy, this may result in an interaction and increase the levels of Ivables 5 Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Ivables 5 Tablet Substitute

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Alcohol

Unsafe

A person taking Ivables 5 Tablet is not allowed to consume alcohol as alcohol may worsen the dizziness.

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Pregnancy

Unsafe

Ivables 5 Tablet is not allowed to be used during pregnancy as it may harm an unborn baby or even can cause premature childbirth. Take effective birth control pills and other contraception methods to avoid the chances of pregnancy.

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Breast Feeding

Unsafe

Women taking Ivables 5 Tablet should not breastfeed their children as it may pass into breast milk to newborns.

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Driving

Unsafe

A person taking Ivables 5 Tablet is not allowed to drive or not to operate any machine, especially at night, as this medicine may cause sudden variation in the brightness of the light.

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Liver

Unsafe

Ivables 5 Tablet is not allowed to use in patients with severe preexisting liver disease. However, this medication only is used in patients with liver disease if prescribed by the doctor.

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Kidney

Unsafe

Take Ivables 5 Tablet is not allowed to use in patients dealing with severe renal disease. Ivables 5 Tablet does not interfere with the functions of kidneys in cardiac heart failure patients, but still, this medicine can only be used after the doctor's recommendation.

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Children

Unsafe

Ivables 5 Tablet is not allowed to use in children below 18 years unless prescribed by the doctor.

FAQs

Ivables 5 Tablet is used to treat symptomatic stable angina pectoris and chronic heart failure.

Ivables 5 Tablet contains Ivabradine which works by reducing the heart rate by a few beats per minute. In this way, it lowers the heart's requirement for oxygen, especially in situations where an angina attack can happen. This helps control or reduce the chances of more angina attacks.

Yes, a woman should always take every measure, including a birth control pill to prevent pregnancy while taking Ivables 5 Tablet as this medicine can harm an unborn baby.

No, Ivables 5 Tablet should not be used in those who are suffering from cardiogenic shock (a potentially fatal condition in which your heart suddenly cannot pump enough blood to fulfil your body's needs).

Reducing heart rate is required in patients dealing with angina and heart failure. When the heart rate gets reduced, the heart can pump more amount of blood into the whole body without affecting the heart's contraction and relaxation.

Country of origin

India

Manufacturer/Marketer address

702, Balaji Business Park, Andheri Kurla Road, Marol Naka, Andheri East, Gamdevi, Marol, Andheri East, Mumbai, Maharashtra 400059
Other Info - IVA0070

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