Istavel D 10/100 Tablet is used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus (also known as non-insulin-dependent diabetes or adult-onset diabetes) is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.

Istavel D 10/100 Tablet contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors) and Sitagliptin (dipeptidyl peptidase-4 inhibitor). Dapagliflozin lowers blood glucose levels and increases the excretion of glucose in the urine. By increasing insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces. Thus, Istavel D 10/100 Tablet helps control blood sugar levels.

Istavel D 10/100 Tablet may cause side effects such as diarrhoea, hypoglycaemia, headache, nausea, and vomiting. These effects do not require medical attention and gradually resolve over time. Inform your doctor if any of these side effects persist or bother you. Take Istavel D 10/100 Tablet as prescribed by your doctor.

Istavel D 10/100 Tablet should be avoided if you are allergic to any of the components in it. Inform your doctor if you are pregnant or breastfeeding. Let your doctor know about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Istavel D 10/100 Tablet is a combination medicine containing Dapagliflozin and Linagliptin as active ingredients. Dapagliflozin helps in removing excess sugar from the body via urine. Linagliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas. Together, Istavel D 10/100 Tablet helps control blood sugar levels.

• Stomach upset
• Hypoglycaemia (low blood sugar levels)
• Nausea
• Vomiting
• Diarrhea
• Headache
• Constipation
• Dizziness
• Runny nose
• Sore throat

Do not take Istavel D 10/100 Tablet if you are allergic to any of its components. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Inform your doctor if you have any liver/kidney disease, heart problems, and hypertension before taking Istavel D 10/100 Tablet . Istavel D 10/100 Tablet is not recommended for children as safety and effectiveness have not been established. Avoid alcohol consumption while taking Istavel D 10/100 Tablet as it might cause unpleasant side effects. It is unknown whether Istavel D 10/100 Tablet can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age.

Drug-Drug Interactions: Istavel D 10/100 Tablet may interact with anti-diabetic (insulin glargine), diuretics (furosemide), hormone (levothyroxine) and corticosteroids.

Drug-Food Interactions: Avoid alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have hypoglycaemia (low blood sugar levels), heart problems and liver/kidney disease.

• INSULIN
• FUROSEMIDE
• LEVOTHYROXINE

• Eat foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables.
• Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
• Follow a healthy diet and walk/exercise for at least 45 minutes.
• Maintain a healthy weight by exercising regularly.
• Rest properly and avoid stress by doing meditation or yoga.

• Regularly monitor blood glucose levels while taking Istavel D 10/100 Tablet .
• Try not to skip any doses and take Istavel D 10/100 Tablet for as long as your doctor has prescribed it for you.
• Always carry a sugary food such as candy or fruit juice and consume them if you experience hypoglycaemia.

Type-2 diabetes mellitus: It is also known as non-insulin-dependent diabetes. It is a chronic or lifelong disease that keeps the body from utilizing insulin properly. Diabetes is a medical condition in which blood glucose levels are above normal. People with type 2 diabetes either do not produce enough insulin, or the produced insulin cannot perform its function in the body (insulin resistance).