Istavel 50 mg Tablet belongs to the group of anti-diabetic medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors) used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus is a condition in which blood sugar is too high because the body does not produce or use insulin normally.

Istavel 50 mg Tablet contains Sitagliptin, which works by blocking the action of DPP-4 (dipeptidyl peptidase-4) and increases the amount of insulin made by the body. Thus, it helps lower blood glucose levels.

In some cases, Istavel 50 mg Tablet may cause side effects such as upper respiratory tract infections, headache, and nasopharyngitis (inflammation of nasal passages). Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if any side effects persist or worsen.

Do not take Istavel 50 mg Tablet if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Istavel 50 mg Tablet is not recommended in children below 18 years. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Istavel 50 mg Tablet contains Sitagliptin, which belongs to the group of anti-diabetic medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Istavel 50 mg Tablet works by blocking the action of DPP-4 (dipeptidyl peptidase-4) and increasing the amount of insulin made by the body. Thus, it helps lower blood glucose levels.

• Upper respiratory tract infections
• Headache
• Nasopharyngitis (inflammation of nasal passages)

Do not take Istavel 50 mg Tablet if you are allergic to any of its components. Inform the doctor if you have kidney or liver problems, pancreatitis (inflammation of the pancreas), gallstones, type 1 diabetes, diabetic ketoacidosis (a complication of diabetes with high blood sugar, rapid weight loss, nausea or vomiting), a history of alcoholism, heart problems/heart failure, or high blood triglyceride levels. Consult the doctor if you are pregnant or breast-feeding. Seek medical attention if you experience symptoms of pancreatitis (severe abdominal pain) or heart failure (shortness of breath, swelling in the legs, unusual tiredness). Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions: Inform the doctor if you are taking anti-diabetic (insulin glargine), diuretic (furosemide), hormone (levothyroxine), or cardiac glycoside(digoxin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have diabetic ketoacidosis, type-1 diabetes, heart problems, or pancreatitis.

• INSULIN GLARGINE
• FUROSEMIDE
• LEVOTHYROXINE
• DIGOXIN

• Include fruits, vegetables, whole grains, and beans in your diet.
• Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
• Maintain a healthy weight by exercising regularly.
• Rest properly.
• Avoid stress by doing meditation or yoga.
• Limit saturated and processed food.
• Stay physically active as it helps manage blood glucose levels. 
• Avoid/limit the consumption of alcohol as it may affect blood sugar levels.

• If you are due to undergo any tests or surgery, inform the doctor that you are taking Istavel 50 mg Tablet.
• Regular monitoring of blood sugar levels is advised.
• It is recommended to stay on your prescribed diet and exercise program while taking Istavel 50 mg Tablet.
• Consult the doctor if you have stress, fever, trauma, infection or surgery. The doctor may adjust the dose in such cases.

Type-2 diabetes mellitus: Type-2 diabetes mellitus, also known as non-insulin-dependent diabetes or adult-onset diabetes, is a chronic or lifelong disease that keeps the body from utilizing insulin (a hormone which controls sugar levels in the blood) properly. It is a medical condition in which blood glucose levels are above normal. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes; hence, it is also known as adult-onset diabetes. Type 2 diabetes symptoms include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.