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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:51 AM IST

Indolous 75 Capsule ER is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. It is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery. It contains Indomethacin, which works by reducing the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience certain common side effects, such as headache, dizziness, diarrhoea, vomiting, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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About Indolous 75 Capsule ER

Indolous 75 Capsule ER is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. Indolous 75 Capsule ER is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery.

Indolous 75 Capsule ER works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Indolous 75 Capsule ER as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, dizziness, diarrhoea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Indolous 75 Capsule ER can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Indolous 75 Capsule ER. Indolous 75 Capsule ER increases the chances of stomach ulcers and bleeding. To treat your condition effectually, continue taking Indolous 75 Capsule ER for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Indolous 75 Capsule ER if you are pregnant or breastfeeding unless prescribed. Indolous 75 Capsule ER causes drowsiness and dizziness, so drive with caution. Indolous 75 Capsule ER should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Indolous 75 Capsule ER as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Indolous 75 Capsule ER

Treatment of Osteoarthritis, Ankylosing spondylitis, Rheumatoid arthritis.

Medicinal Benefits

Indolous 75 Capsule ER belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Indolous 75 Capsule ER is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. Indolous 75 Capsule ER is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery. Indolous 75 Capsule ER works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Directions for Use

Take this medicine with or immediately after food or with milk or antacids. Take it at the same time every day for the best results. Swallow Indolous 75 Capsule ER as a whole with a glass of water or milk; do not chew, break, or crush the tablet.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Indolous 75 Capsule ER

  • Headache,
  • Dizziness
  • Diarrhoea
  • Vomiting
  • Constipation

Drug Warnings

Indolous 75 Capsule ER can increase your risk of having a fatal heart attack, chest pain (angina) or stroke. So, tell your doctor that you are using Indolous 75 Capsule ER before undergoing heart bypass surgery (CABG) or graft surgery. Do not take Indolous 75 Capsule ER if you are allergic to Indolous 75 Capsule ER, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Do not take Indolous 75 Capsule ER if you are pregnant or breastfeeding unless prescribed. Indolous 75 Capsule ER causes drowsiness and dizziness, so drive only if you are alert. Indolous 75 Capsule ER should not be given to children as the safety have not been established. Avoid consuming alcohol along with Indolous 75 Capsule ER as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Indolous 75 Capsule ER and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach like blood in stools.

Drug Interactions

Drug-Drug Interactions: Indolous 75 Capsule ER may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol (used to treat high blood pressure), celecoxib, and prednisone (used to treat arthritis).

Drug-Food Interactions: Avoid consuming alcohol along with Indolous 75 Capsule ER as it could lead to increased drowsiness and dizziness. It could also elevate the risk of stomach bleeding.

Drug-Disease Interactions: Indolous 75 Capsule ER should not be given in patients with heart failure, fluid retention (oedema), asthma, gastrointestinal toxicity, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), rash, platelet aggregation inhibition, CNS problems, kidney and liver toxicity.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ASPIRIN
  • DULOXETINE
  • METOPROLOL
  • CELECOXIB
  • PREDNISONE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Special Advise

  • Your doctor may advise you to undergo tests for monitoring liver and kidney functioning, blood cell levels, effect on stomach and intestine.

  • Regular monitoring of eye-sight via eye tests is advised if you have rheumatoid arthritis.

  • Monitoring of blood pressure levels and heart functioning is recommended.

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, inflammation, stiffness, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear-out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include stiffness, pain, swelling, deformities and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine, which starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility, which usually leads to a hunched-forward posture and pain in the back and joints. 

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Indolous 75 Capsule ER. Alcohol intake, along with Indolous 75 Capsule ER, may cause increased dizziness and drowsiness. It may also elevate the risk of stomach bleeding.

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Pregnancy

Unsafe

It is not recommended to take Indolous 75 Capsule ER while you are pregnant. Please consult your doctor if you are pregnant or if you are having any concerns regarding this.

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Breast Feeding

Unsafe

It is not recommended to take Indolous 75 Capsule ER while you are breastfeeding. Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this.

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Driving

Caution

Indolous 75 Capsule ER may cause drowsiness, dizziness, tiredness and vision disturbances, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Indolous 75 Capsule ER should be taken with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver problems with symptoms of yellowing of skin/eyes, difficulty in peeing or feeling exhausted all the time.

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Kidney

Caution

Dose adjustment may be needed. Indolous 75 Capsule ER should be taken with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Indolous 75 Capsule ER should not be used by children, as the efficacy and safety have not been established.

Country of origin

India
Other Info - IN51539

Author Details

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FAQs

Indolous 75 Capsule ER is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. It is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery.
Indolous 75 Capsule ER works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.
Indolous 75 Capsule ER causes drowsiness, dizziness, tiredness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
Diarrhoea might be a side-effect of Indolous 75 Capsule ER. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Indolous 75 Capsule ER for longer durations or high doses as it may cause a heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.
Indolous 75 Capsule ER may increase the risk of heart attack or stroke. Do not use Indolous 75 Capsule ER immediately before or after heart surgery. Consult your doctor before taking Indolous 75 Capsule ER if you have/ had heart problems.
Indolous 75 Capsule ER may affect laboratory test results. Inform the person doing the tests that you are taking Indolous 75 Capsule ER.
Indolous 75 Capsule ER may affect fertility. However, the effect is reversible on stopping Indolous 75 Capsule ER. Consult your doctor before taking Indolous 75 Capsule ER if you are planning to become pregnant. It is important not to become pregnant while using Indolous 75 Capsule ER and for at least 1 month after stopping Indolous 75 Capsule ER as it can cause harm to the unborn baby or fetus. Women can be given a reminder card from the doctor about this.
The common side effects of Indolous 75 Capsule ER include sensitivity to sunlight, dry eyes, dry throat, dry nose and nosebleeds, headaches and general aches and pains.
Yes, Indolous 75 Capsule ER is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate acute pain.
In some cases, you may experience headache as a common side effect. In most cases it does not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience headache persistently.
No, Indolous 75 Capsule ER is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and relieves pain.
The time it takes to see results with Indolous 75 Capsule ER may vary depending on many factors. It's important to follow the recommended dosage and treatment regimen and to consult with a healthcare professional for ongoing monitoring.
Indolous 75 Capsule ER contains Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID).
Inform your doctor about your dietary habits, medications, and underlying health issues. Your doctor will only recommend this if the benefits outweigh the risks.
The recommended dosage may vary depending on your individual needs and the condition being treated. It's best to follow the instructions provided on the product label or as directed by your healthcare provider.
The frequency of intake will depend on your specific situation. Follow the instructions provided or consult with your healthcare provider.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Indolous 75 Capsule ER contains Indomethacin, it has been shown to be an effective.

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