Ignalis-M IR 50 mg/500 mg Tablet 10's
₹83.6*
MRP ₹95
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Ignalis-M Ir 50/500 Tab is a combination drug of Sitagliptin (DPP4 inhibitors) and Metformin (Biguanides), belonging to the class of anti-diabetic agents used to treat type II diabetes. Type 2 diabetes is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood), or there is resistance to the action of insulin. As a result, insulin is produced in large amounts, but it cannot act on the body's organs.
Sitagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors that work by increasing the amounts of certain natural substances that lower blood sugar when it is high. Another medicine, Metformin, belongs to the class of biguanides that lower glucose production in the liver, delay glucose absorption from the intestines, and increase the body's sensitivity to insulin. Thus, Ignalis-M Ir 50/500 Tab controls blood glucose levels from rising to very high levels after meals.
Ignalis-M Ir 50/500 Tab should be taken with food to avoid an upset stomach. Ignalis-M Ir 50/500 Tab should be taken at the same time of the day each time for best results. For better advice, your doctor will decide what dose should be taken, and it can change in time depending on your condition. The most common side effect of Ignalis-M Ir 50/500 Tab is hypoglycemia (low blood glucose levels), characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycemia, you should not miss meals and should also carry some form of sugar with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.
Ignalis-M Ir 50/500 Tab should not be stopped even if you feel better, without consulting the doctor as your sugar level keeps changing. If you stop taking Ignalis-M Ir 50/500 Tab abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Ignalis-M Ir 50/500 Tab should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, are planning to get pregnant or are breastfeeding.
Ignalis-M Ir 50/500 Tab helps the pancreas produce more insulin, effectively utilise insulin, and decrease the excess sugar the liver makes. It helps control the rise of blood sugar levels after a meal. Besides this, it does not cause weight gain in prolonged use. Ignalis-M Ir 50/500 Tab plays a vital role in controlling blood sugar levels. It prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
Ignalis-M Ir 50/500 Tab should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Ignalis-M Ir 50/500 Tab , might develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid accumulates in the blood, which can damage the workings of your liver and kidneys, which are required to eliminate excess lactic acid from the blood. Before you start taking Ignalis-M Ir 50/500 Tab , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 levels. Ignalis-M Ir 50/500 Tab , when used with insulin, Ignalis-M Ir 50/500 Tab may lower the blood sugar level, leading to hypoglycaemia, which can be fatal. In this case, your doctor may adjust the dose by lowering the insulin dose or Ignalis-M Ir 50/500 Tab . Prolonged intake of Ignalis-M Ir 50/500 Tab may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you will have a diagnostic test with an injection of dye or X-ray contrast agent. You should stop using Ignalis-M Ir 50/500 Tab briefly before an X-ray procedure.
Drug-Drug Interactions: Ignalis-M Ir 50/500 Tab interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-HIV drugs (dolutegravir), ethanol, saliva reducing drugs (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine). Other drug interactions can contribute to increased low blood sugar, including sex hormones (androgens), anti-oxidants (alpha-lipoic acid), pain killers (aspirin), anti-TB drugs (prothionamide), growth hormones (pegvisomant), and other antidiabetic medicines.
Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Ignalis-M Ir 50/500 Tab .
Drug-Disease Interactions: People affected with heart diseases (like congestive heart failure and myocardial infarction), Vitamin B12 deficiency, and alcoholism should avoid intake of Ignalis-M Ir 50/500 Tab .
Type 2 diabetes is a condition where the body cannot make sufficient insulin, or the insulin it makes doesn't work properly or is utilized by our body. This can cause high blood sugar levels (hyperglycaemia). Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increase in the chance of heart attack or stroke.
Alcohol
Caution
Avoid consumption of alcohol while on treatment with Ignalis-M Ir 50/500 Tab .
Pregnancy
Caution
Ignalis-M Ir 50/500 Tab is only recommended during pregnancy when the benefit outweighs the risk. Please consult your doctor before starting Ignalis-M Ir 50/500 Tab if you are pregnant or planning to conceive.
Breast Feeding
Caution
Consult your doctor; Ignalis-M Ir 50/500 Tab should be used in breastfeeding mothers only if the benefits outweigh the risks.
Driving
Caution
Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking these medications you should not drive or operate any machinery or vehicles.
Liver
Caution
If you have or have a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.
Kidney
Caution
If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.
Children
Caution
It is advisable to consult a doctor before using it.
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