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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Dec 7, 2024 | 2:25 PM IST
Ibivig 5gm Injection is used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders. It contains Human normal immunoglobulin which helps the body fight against infections and works the same way as natural immunoglobulins. In some cases, this medicine may cause side effects such as injection site reactions, headache, fever, flu-like symptoms, and throat tightness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ibivig 5gm Injection

Ibivig 5gm Injection belongs to the class of medications called ‘immunising agents’ used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). Ibivig 5gm Injection is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).

Ibivig 5gm Injection contains ‘Human normal immunoglobulin’, which replaces the deficient antibodies necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an essential part of the immune system, which recognises the antigens or foreign elements in the body and aids in their destruction. It also helps to reduce inflammation by improving immunity.

Ibivig 5gm Injection will be administered by a trained healthcare professional; hence do not self-administer. This may cause side effects such as swelling or hardening at the injection site and headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth, and throat, and throat tightness. These side effects are usually mild and temporary. However, if any of the side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Ibivig 5gm Injection if you are allergic to any of its contents or have blood clotting disorders. Before taking Ibivig 5gm Injection , inform your doctor if you have had any vaccinations recently or have already had this product recently. Ibivig 5gm Injection should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections). Ibivig 5gm Injection is probably safe when given to children, pregnant women, and breastfeeding mothers. Ibivig 5gm Injection should be used with caution in elderly people. Ibivig 5gm Injection may not interact with alcohol. Ibivig 5gm Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Ibivig 5gm Injection

Treatment of Immunoglobulin deficiency and inflammatory disorders such as primary immune thrombocytopenia, Guillain-Barre syndrome, Kawasaki disease, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy.

Medicinal Benefits

Ibivig 5gm Injection acts by replacing the deficient antibodies that are necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an important part of the immune system, which recognizes the antigens or foreign elements in the body and causes their destruction. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). Ibivig 5gm Injection is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).

Directions for Use

A trained healthcare professional will administer Ibivig 5gm Injection , so do not self-administer. The injection is given subcutaneously (under the skin), whereas infusion is given via intravenous (into the vein) route.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ibivig 5gm Injection

  • Swelling or hardening at the injection site
  • Headache
  • Pain in the face, back, arms, legs, joints, or neck
  • Fever
  • Flu-like illness (runny nose and sore throat)
  • Blisters in the mouth and throat
  • Throat tightness

Drug Warnings

Ibivig 5gm Injection should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections) as there is an increased risk of allergic reactions. Ibivig 5gm Injection may cause a sudden fall in blood pressure with an allergic reaction, including shock, even in patients who have tolerated previous treatment with this medicine. So, it is advised to monitor patients during infusion and at least 20 min after the infusion. If you develop a severe headache, drowsiness, fever, neck stiffness, sensitivity to light, nausea, and vomiting after Ibivig 5gm Injection , inform your doctor immediately. It may signify aseptic meningitis syndrome (severe inflammation of the brain's linings). Ibivig 5gm Injection should be used with caution in people with obesity or overweight, diabetes, high blood pressure (hypertension), hypovolemia (low blood volume), and blood clotting disorders, as there is a risk of developing a blood clot (very rare effect of Ibivig 5gm Injection ). So, inform your doctor if you notice any sign of a blood clot, such as pain, swelling and unusual warmth of a limb, weakness on one side of the body, confusion, sudden shortness of breath, chest pain worsening on deep breathing, and difficulty speaking. Ibivig 5gm Injection should be used with caution in patients with kidney problems or who have taken medicines that may harm kidneys (nephrotoxic drugs) as Ibivig 5gm Injection may cause problems with kidney function in these people. In rare cases, Ibivig 5gm Injection may cause non-cardiogenic pulmonary oedema (accumulation of fluid in the lungs' air spaces, which is a non-heart related condition). In such cases, patients may experience breathing difficulty, bluish skin, and very low oxygen levels in the blood.

Drug Interactions

Drug-Drug Interactions: Ibivig 5gm Injection may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Ibivig 5gm Injection should be used with caution in people with blood clotting disorders and immunoglobulin A (IgA) deficiency.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • ETHACRYNIC ACID
  • MMR VACCINE
  • VARICELLA (LIVE ATTENUATED)

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet that includes grains,  fresh fruits, vegetables, lean meats, and dairy products. 
  • Stay active and do moderate exercises every day. Maintain a normal weight.
  • Get enough sleep, as sleep and immunity are closely related.
  • Limit intake of sugar-rich foods or drinks.
  • Stay hydrated. 
  • Practice good hygiene.
  • Manage stress levels. 

Special Advise

  • Ibivig 5gm Injection  should not be given intravenously.
  • The side effects can be reduced or sometimes avoided by giving the Ibivig 5gm Injection  at a slow rate.
  • The patient should be observed during the whole infusion and for at least 20 min after giving the Ibivig 5gm Injection to exclude any development of the allergic reaction.
  • It is strongly recommended that each time a dose of Ibivig 5gm Injection is given, the name and batch number of the medicine should be recorded to maintain a record of the batches used.
  • Ibivig 5gm Injection may alter some blood test results for a certain time, so inform your doctor that you have Ibivig 5gm Injection before undergoing blood tests.
  • Ibivig 5gm Injection should be used with caution in patients with diabetes as it may alter blood sugar levels. Ibivig 5gm Injection doesn’t contain sugar; however, it can be diluted in a special sugar solution before giving the infusion.
  • Do not take any vaccines (especially live vaccines) at least three months after taking Ibivig 5gm Injection as this medicine may make the vaccine less effective. 

Disease/Condition Glossary

Immunoglobulin deficiency: Immunoglobulin deficiency indicates low levels of antibodies in the body due to decreased ability or inability to produce enough antibodies. It can be primary immunodeficiency (PID) and acquired or secondary immunodeficiency (SID). PID is congenital and a disorder present from birth. In PID, there is. On the other hand, SID is an acquired disorder that you get later in life.  Immunoglobulin deficiency can lead to recurrent infections and ineffective antimicrobial treatment.

Primary immune thrombocytopenia: In this condition, platelet levels are decreased in the blood. This condition causes easy bruising or bleeding. Children may also experience purplish spots on the lower legs. In children, this condition usually resolves without any treatment. However, adults may require treatment to control bleeding.  

Guillain-Barre syndrome: It is a rare condition in which the immune system attacks the nerves due to an acute bacterial or viral infection. Symptoms include weakness and tingling in the legs and feet that can spread to the upper body. Some patients may also develop paralysis.

Kawasaki disease: It is the inflammation of the blood vessels that is characterized by rashes and fever. It can also affect lymph nodes and cause symptoms in your nose, mouth, and throat. This condition is seen in young infants and children.

Chronic inflammatory demyelinating neuropathy (CIDP): It is a condition in which nerves in the body are affected. Symptoms include slow reflexes and weakness of the arms and legs.

Multifocal motor neuropathy: It is a condition in which motor nerves (nerves that control movements and actions) are affected due to abnormal responses of the immune system. Symptoms include weakness in the upper and lower arms, cramps, involuntary twitching, and atrophy (wasting) of affected muscles.

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Alcohol

Safe if prescribed

Ibivig 5gm Injection may not interact with alcohol. However, limit or avoid consumption of alcohol to avoid possible side effects.

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Pregnancy

Safe if prescribed

Inform your doctor if you are pregnant or planning pregnancy before receiving Ibivig 5gm Injection . Your doctor will assess the benefits and the risks before prescribing.

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Breast Feeding

Safe if prescribed

Inform your doctor if you are breastfeeding before receiving Ibivig 5gm Injection . Your doctor will assess the benefits and the risks before prescribing.

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Driving

Caution

Ibivig 5gm Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after receiving this medicine.

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Liver

Caution

Ibivig 5gm Injection should be used with caution in patients with liver diseases. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

Ibivig 5gm Injection should be used with caution in patients with kidney diseases. Your doctor may adjust the dose if necessary based on your condition.

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Children

Safe if prescribed

Ibivig 5gm Injection can be safely used in children when prescribed.

Country of origin

India

Manufacturer/Marketer address

Flat No 302, 3Rd Floor, Unicon Foland 2Nd Main, Reshme Nagar, Hosahalli Villag Bsk 6Th Stage Bangalore Ka 560062 In
Other Info - IBI0035

Author Details

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FAQs

Ibivig 5gm Injection is used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders.
The Ibivig 5gm Injection contains 'Human normal immunoglobulin', which helps restore the deficient immunoglobulins or antibodies in the body. Antibodies are an essential part of the immune system that helps to reduce infection and inflammation. They act by identifying, attacking, and thereby destroying the antigen or foreign body that has entered or is present in the body.
Ibivig 5gm Injection may alter some blood test results for a certain time, so inform your doctor that you have Ibivig 5gm Injection before undergoing blood tests. Taking any vaccines (especially live vaccines) at least three months after taking Ibivig 5gm Injection is not recommended as this medicine may make the vaccines less effective.
Ibivig 5gm Injection should be used with caution in patients with diabetes if this medicine is given as an infusion, as it may alter blood sugar levels. Ibivig 5gm Injection doesn’t contain sugar; however, it can be diluted in a special sugar solution before giving the infusion.
Ibivig 5gm Injection is usually well-tolerated. However, some patients may experience side effects such as swelling or hardening at the injection site and headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth, and throat, and throat tightness. If any side effects persist or get worse, inform your doctor immediately.
It is a condition in which there is a decrease in antibody levels in the body due to decreased ability or inability to produce enough antibodies. It can be present from birth (primary) or acquired during the later stages of life (secondary).
Certain vaccinations, such as those for chickenpox, measles, mumps, and rubella, may become less effective when administered with Ibivig 5gm Injection . Therefore, before receiving any vaccinations, inform your doctor if you are allergic to Ibivig 5gm Injection . Let your doctor know that you are taking Ibivig 5gm Injection . And also inform your doctor if you are breastfeeding, pregnancy or planning pregnancy.
No, you should not discontinue using Ibivig 5gm Injection without consulting your doctor, even if you feel fine. Stopping the usage of Ibivig 5gm Injection early can increase the risk of infections. Always follow your doctor's instructions and complete the prescribed course of treatment to ensure the best outcome.
The effects of Ibivig 5gm Injection can vary depending on the individual and the condition being treated. Generally, it may take up to 4 weeks of regular therapy to notice a steady improvement in your symptoms. Therefore, complete the full course of treatment as prescribed by your doctor.
Yes, Ibivig 5gm Injection can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, hypovolemia (a decrease in the volume of circulating blood) and diabetes are at risk of developing kidney failure. Additionally, patients who are overweight, above 65 years of age and who are taking medicines that can cause kidney damage are also at risk of developing kidney failure. Therefore, please inform your doctor if you have any pre-existing kidney problems.
No, hair loss is not a commonly reported side effect of Ibivig 5gm Injection . If you experience hair loss, it might be due to some other underlying problem. Please consult your doctor if bothers you.
Ibivig 5gm Injection benefits people with weakened immune systems, such as those who have undergone bone marrow transplants or have severely reduced antibody-forming capacity. It can also treat or prevent infections who are suffering with measles, hepatitis, and mumps. It is used for patients with primary immunodeficiency syndromes (PID) and acquired or secondary immunodeficiency (SID). Please consult your doctor if you have any concerns.
If you are pregnant, take your doctor’s advice before using Ibivig 5gm Injection . Your doctor will assess the benefits and risks of Ibivig 5gm Injection before prescribing.
Store Ibivig 5gm Injection in a refrigerator (2 - 8°C). Do not freeze. Protect it from light. Keep out of reach of children.
No, Ibivig 5gm Injection should not be self-administered. It is usually administered by a healthcare professional, such as a doctor or nurse.

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Keep Refrigerated. Do not freeze.