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Prescription drug
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Manufacturer/Marketer

Gnosis Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Hqra 400 Mg Tablet

Hqra 400 Mg Tablet belongs to the class of 'anti-inflammatory drugs.' It has various medical uses, including treatment for type 2 diabetes mellitus, acute or chronic rheumatoid arthritis, dyslipidaemia (abnormally elevated cholesterol levels), systemic and discoid lupus erythematosus (autoimmune disease), polymorphous light eruption (a rash caused by sun exposure), and malaria. 

Hqra 400 Mg Tablet contains Hydroxychloroquine, an anti-inflammatory drug. For diabetes, it works by improving insulin sensitivity and increasing insulin secretion. In rheumatoid arthritis, Hydroxychloroquine acts as a mild immunosuppressant and disease-modifying anti-rheumatic agent and inhibits the production of rheumatoid factor. It also decreases the severity of skin lesions in systemic and discoid lupus erythematosus. In malaria, it works by increasing the concentration of a toxic compound in the parasite that leads to its death.

Take this medicine as prescribed by a doctor. Hqra 400 Mg Tablet may cause common side effects like blurred vision, abdominal pain, nausea, vomiting, loss of appetite, diarrhoea, headache, mood changes, skin rashes, itching, sensitivity to light, and pigmentation disorders. These side effects are not familiar to everyone and may vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Before taking Hqra 400 Mg Tablet , please inform your doctor if you are allergic to medicines, liver/kidney/heart diseases, gastrointestinal problems, blood disorders, and brain-related problems. Pregnant and breastfeeding women should consult their doctor before starting Hqra 400 Mg Tablet . Hqra 400 Mg Tablet may cause blurred vision; hence do not drive or operate machinery until you feel better. The safety and efficacy of Hqra 400 Mg Tablet have not been established in children; please seek medical advice for more information.

Uses of Hqra 400 Mg Tablet

Treatment of Type 2 diabetes mellitus, acute or chronic rheumatoid arthritis, dyslipidaemia, systemic and discoid lupus erythematosus, polymorphous light eruption, and malaria

Medicinal Benefits

Hydroxychloroquine has diversified medical uses and works by reducing inflammation in people with autoimmune diseases. It helps treat type 2 diabetes mellitus and autoimmune conditions like rheumatoid arthritis, systemic lupus erythematosus, and malaria. For diabetes, it works by improving insulin sensitivity and increasing insulin secretion. In rheumatoid arthritis, Hydroxychloroquine acts as a mild immunosuppressant and disease-modifying anti-rheumatic agent and inhibits the production of rheumatoid factor. In malaria, it works by increasing the concentration of a toxic compound in the parasite that leads to its death. Hydroxychloroquine is an anti-thrombotic and anti-platelet agent that helps reduce abnormally elevated cholesterol levels. It also decreases the severity of skin lesions in systemic and discoid lupus erythematosus.

Side Effects of Hqra 400 Mg Tablet

  • Blurred vision
  • Abdominal pain
  • Nausea
  • Vomiting
  • Loss of appetite
  • Diarrhoea
  • Headache
  • Mood changes
  • Skin rashes
  • Itching
  • Sensitivity to light
  • Pigmentation disorders

Directions for Use

Swallow Hqra 400 Mg Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before using Hqra 400 Mg Tablet , inform your doctor if you have recently used any prescription and non-prescription medications. Keep your doctor informed of your medical history before starting Hqra 400 Mg Tablet . Please seek medical advice if you are pregnant or breastfeeding before taking Hqra 400 Mg Tablet . This medicine may cause blurred vision; hence drive or operate machinery only when you are alert and have clear vision. Avoid alcohol consumption while being treated with Hqra 400 Mg Tablet . Safety and efficacy of Hqra 400 Mg Tablet have not been established in children.

Therapeutic Class

ANTIDIABETICS

Drug Interactions

Drug-Drug Interaction: Hqra 400 Mg Tablet may interact with anti-cancer drugs (tamoxifen), heart-related medicines (digoxin, amiodarone), anti-diabetic drugs (insulin), anti-malarial drugs (halofantrine, mefloquine), antibiotics (moxifloxacin, azithromycin, penicillamine), immunosuppressants (ciclosporin), heartburn medicines (cimetidine), antipsychotics (amisulpride, quetiapine), fits medicines, and anticoagulants.

Drug-Food Interaction: Avoid alcohol consumption while using Hqra 400 Mg Tablet .

Drug-Disease Interaction: Before using Hqra 400 Mg Tablet , let your doctor know if you have any medical history of liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency (a genetic enzyme deficiency), high blood pressure, serious stomach or gut problems, nervous system problems, psoriasis, porphyria (a blood disorder), history of heart attack (myocardial infarction), electrolyte imbalance, fits, damaged retina or vision problems, and allergic reactions to medicines.

Drug-Drug Interactions Checker List

  • TAMOXIFEN
  • DIGOXIN
  • AMIODARONE
  • HALOFANTRINE
  • MEFLOQUINE
  • MOXIFLOXACIN
  • AZITHROMYCIN
  • PENICILLAMINE
  • CICLOSPORIN
  • CIMETIDINE
  • AMISULPRIDE
  • QUETIAPINE
  • INSULIN HUMAN

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Notice and manage the early symptoms of high/low blood sugar levels.
  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.
  • Include high-fibre foods like green leafy vegetables and fruits to aid digestion.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

What if I have taken an overdose of Hqra 400 Mg Tablet

Never take more than the prescribed dose. Overdose of Hqra 400 Mg Tablet may cause drowsiness, increased thirst, loss of appetite, mood changes, no pulse or blood pressure, numbness or tingling in the hands, feet, or lips, and unconsciousness. If an overdose is suspected, seek immediate medical help.

Special Advise

  • Let your doctor/laboratory staff know that you are taking Hqra 400 Mg Tablet if you undergo medical tests.
  • While being treated with Hqra 400 Mg Tablet , your doctor may suggest ECG (electrocardiogram) to monitor your heart health.
  • Your doctor may also suggest tests for blood cell counts (during prolonged therapy) and liver and kidney function tests.

Disease/Condition Glossary

Diabetes mellitus: It is also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance), or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people above 40 years but can also occur in childhood based on the risk factors. 

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Symptoms include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools.

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. 

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Alcohol

Caution

Avoid alcohol while using Hqra 400 Mg Tablet since it can worsen your side effects and may interfere with the working of the medicine.

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Pregnancy

Unsafe

Hqra 400 Mg Tablet is not recommended during pregnancy. Please seek medical advice if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Hqra 400 Mg Tablet is not recommended during lactation since it is excreted into the breast milk. Please consult your doctor before starting Hqra 400 Mg Tablet if you are a breastfeeding mother.

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Driving

Caution

Hqra 400 Mg Tablet may cause blurry vision affecting your ability to drive or operate. In such cases, do not drive or operate machinery until you are alert and have a clear vision.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Hqra 400 Mg Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Hqra 400 Mg Tablet .

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Children

Caution

Safety and efficacy of Hqra 400 Mg Tablet have not been established in children; please seek medical advice for more information.

Country of origin

India

Manufacturer/Marketer address

Via Lavoratori Autobianchi, 1, 20832 Desio (MB) - Italy
Other Info - HQR0001

Author Details

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FAQs

Hqra 400 Mg Tablet is used to treat type 2 diabetes mellitus, acute or chronic rheumatoid arthritis, dyslipidaemia (abnormally elevated cholesterol levels), systemic and discoid lupus erythematosus (autoimmune disease), polymorphous light eruption (a rash caused by sun exposure), and malaria.
Hqra 400 Mg Tablet contains Hydroxychloroquine, an anti-inflammatory drug that reduces inflammation in people with autoimmune disorders. Hydroxychloroquine improves insulin sensitivity in diabetes and has a hypoglycaemic effect. It is a disease-modifying anti-rheumatic agent that inhibits the production of rheumatoid factor in rheumatoid arthritis. It also decreases the elevated cholesterol levels in the body and reduces the risk of cardiovascular diseases. Hydroxychloroquine is also an anti-malarial drug that treats malaria by increasing the concentration of a toxic compound in the parasite that leads to its death.
Inform your doctor in advance if you have any liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency (a genetic enzyme deficiency), high blood pressure, serious stomach or gut problems, nervous system problems, psoriasis, porphyria (a blood disorder), history of heart attack (myocardial infarction), electrolyte imbalance, fits, and allergic reactions to medicines.
Hqra 400 Mg Tablet may cause drug-induced retinopathy (disease related to the retina) when taken more than recommended. You may not be advised Hqra 400 Mg Tablet by your doctor if you have vision changes or damage to your retina. If the doctor has prescribed you this medicine knowing your medical history, you may be further advised to take ophthalmological examinations, including visual acuity, ophthalmoscopy, fundoscopy, and visual field tests. If there are any changes in these examinations, you may be asked to discontinue the treatment.
Hydroxychloroquine may sometimes affect mental health and cause problems like irrational thoughts, anxiety, hallucinations, feeling confused or feeling depressed, including thoughts of self-harm or suicide. Hence, you should speak to your doctor before using Hqra 400 Mg Tablet .
The side effects of Hqra 400 Mg Tablet include headache, blurred vision, stomach pain, nausea, vomiting, and diarrhoea. If these side effects persist or worsen, please consult your doctor.
Hqra 400 Mg Tablet is currently under study in several clinical trials (research studies in human beings) to treat patients with COVID-19 (the illness caused by the novel coronavirus) and to prevent the spread of new coronavirus infection. Hqra 400 Mg Tablet has shown some activity against the novel coronavirus in laboratory studies (in vitro studies). However, to determine whether Hqra 400 Mg Tablet is effective against the novel coronavirus, further evidence is needed.
The use of Hqra 400 Mg Tablet for prevention of novel coronavirus infection has been recommended by the national task force for COVID-19 (constituted by ICMR). It is only for use in certain high-risk populations (ie people at high risk of exposure to the virus) or emergency situations. It can be used for prophylaxis in case of asymptomatic healthcare workers involved in the care of confirmed or suspected cases of COVID-19 and asymptomatic household contacts of laboratory-confirmed cases.
No, we do not need to maintain a stock of Hqra 400 Mg Tablet . If you think you may have the new coronavirus infection, consult a doctor immediately and follow their advice strictly. Do not self-administer Hqra 400 Mg Tablet . Remember that it should be taken only if prescribed by a doctor.
Your doctor will prescribe the dose and duration of Hqra 400 Mg Tablet . Follow your doctor’s instructions strictly.
Hqra 400 Mg Tablet should be taken as advised by the doctor. Take it with a meal or glass of milk to prevent nausea and stomach upset. Swallow it as whole. Do not crush, break or chew it.
If someone becomes symptomatic or shows symptoms of novel coronavirus such as dry cough, high fever, difficulty in breathing or tiredness while taking Hqra 400 Mg Tablet , they should consult their doctor immediately. The doctor will recommend if they require isolation or if they need to get tested for the novel coronavirus. They need to follow all the instructions given by the doctor.
Hqra 400 Mg Tablet may take a few weeks or months to show improvement in your symptoms of rheumatoid arthritis or other autoimmune diseases. However, it is important that you be patient and keep taking it regularly. In the meanwhile, your doctor may prescribe some additional medications to provide temporary relief from the symptoms.
Before starting treatment with Hqra 400 Mg Tablet , you must get an eye test and it should be repeated every12 months. Additionally, your doctor may recommend routine checks for your blood counts (CBC) and liver function test (LFT). If any abnormality is detected, your doctor may discontinue Hqra 400 Mg Tablet .
Hqra 400 Mg Tablet contains Hydroxychloroquine, an anti-malarial drug with anti-inflammatory and immunomodulatory properties. It is neither an opioid, nor a painkiller nor a steroid. Hqra 400 Mg Tablet increases the concentration of a toxic compound in the parasite that leads to its death. It reduces inflammation in people with autoimmune disorders. It is a disease-modifying anti-rheumatic agent that inhibits the production of rheumatoid factor in rheumatoid arthritis.
Yes, you may take ibuprofen with Hqra 400 Mg Tablet as there are no interactions found between them. However, always please consult your doctor before taking other medicines with Hqra 400 Mg Tablet .
If you stop taking Hqra 400 Mg Tablet without doctor’s consultation, your illness may worsen. Therefore, even if you start feeling better, do not stop taking Hqra 400 Mg Tablet without first consulting your doctor.
Yes, you need to be careful while using Hqra 400 Mg Tablet if you are diabetic as it may lower your blood glucose levels to dangerous levels so much resulting in loss of consciousness (severe hypoglycemia). Make sure to monitor your blood glucose levels regularly and if it begins to drop, contact your doctor immediately. Your doctor may change the doses of your anti-diabetic medications as per your blood glucose levels.
Yes, you may take Hqra 400 Mg Tablet but maintain a gap of minimum 4 hours between Hqra 400 Mg Tablet and antacid. If this gap is not maintained, then the antacid may interfere with the working or absorption of Hqra 400 Mg Tablet . Thereby, you may not experience the full benefits of Hqra 400 Mg Tablet .

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