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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Hopace H 5 Capsule is prescribed alone or in combination with other drugs to lower the raised blood pressure. It contains Ramipril and Hydrochlorothiazide, which relaxes the blood vessels and therefore helps lower high blood pressure. Also, it works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Sometimes, you may experience side effects such as headaches, tiredness, slow heart rate, and nausea.
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Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Hopace H 5 Capsule

Hopace H 5 Capsule is prescribed alone or in combination with other drugs to lower the raised blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Hopace H 5 Capsule contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes. 

You can take Hopace H 5 Capsule with a meal or after/before a meal. Your doctor will advise you on the exact dosage and how often you have to take Hopace H 5 Capsule based on your medical condition. Sometimes, you may experience headaches, tiredness, slow heart rate, and nausea. Most of these side effects of Hopace H 5 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Hopace H 5 Capsule may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery.

Try not to stop taking this medicine of your own. You should not stop using the Hopace H 5 Capsule even if your blood pressure becomes normal. Doing so may worsen your condition. Tell your doctor if you have had or currently have liver, kidney, or heart problems. Hopace H 5 Capsule is not recommended in pregnancy and lactation. You should regularly monitor your blood pressure and heart rate. Please tell your doctor if you are taking any other medicines or are allergic to Hopace H 5 Capsule . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Hopace H 5 Capsule

Treatment of Hypertension (high blood pressure)

Directions for Use

Swallow Hopace H 5 Capsule as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Hopace H 5 Capsule contains Ramipril and hydrochlorothiazide. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing the chances of heart attack or stroke. However, Hopace H 5 Capsule does not cure high blood pressure (hypertension) but does help control it. In addition to this, Hopace H 5 Capsule also reduces the physical effects of anxiety.

How Hopace H 5 Capsule Works

Hopace H 5 Capsule contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hopace H 5 Capsule

  • Feeling dizzy or lightheaded
  • Headache
  • Diarrhoea
  • Being sick
  • Mild skin rash
  • Blurred vision
  • Hypotension
  • Nausea (feeling sick)

What if I have taken an overdose of Hopace H 5 Capsule

Do not take more than the prescribed dose of Hopace H 5 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Hopace H 5 Capsule should not be given to the people allergic to Hopace H 5 Capsule , have low blood pressure (less than 90 mm of Hg), have had a heart attack, diabetes, kidney disease, liver disease, are pregnant women, or planning to get pregnant and breastfeeding women. Hopace H 5 Capsule may alter your blood sugar level, so tell your doctor about this before using Hopace H 5 Capsule . Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), and aortic stenosis (heart valve problem). Hopace H 5 Capsule can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Hopace H 5 Capsule and breastfeeding. Do not consume alcohol with Hopace H 5 Capsule as it may increase the risk of low blood pressure. Avoid potassium supplements with Hopace H 5 Capsule as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking Hopace H 5 Capsule . Drink a lot of fluids as Hopace H 5 Capsule can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Hopace H 5 Capsule:
Taking aliskiren together with Hopace H 5 Capsule may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Hopace H 5 Capsule with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Hopace H 5 Capsule:
Taking Cisapride and Hopace H 5 Capsule can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Hopace H 5 Capsule together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Hopace H 5 Capsule:
Taking Dofetilide and Hopace H 5 Capsule can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Hopace H 5 Capsule together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RamiprilLosartan
Severe
How does the drug interact with Hopace H 5 Capsule:
Coadministration of Hopace H 5 Capsule together with losartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Losartan with Hopace H 5 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilAmiloride
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Hopace H 5 Capsule and amiloride together may increase the levels of potassium in your blood.

How to manage the interaction:
Although taking amiloride along with Hopace H 5 Capsule can result in an interaction, they can be taken together if prescribed by a doctor. However, consult the doctor if you feel weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting a doctor.
RamiprilIrbesartan
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Hopace H 5 Capsule together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Hopace H 5 Capsule together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
RamiprilAzilsartan medoxomil
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Azilsartan medoxomil with Hopace H 5 Capsule may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Hopace H 5 Capsule together with Azilsartan medoxomil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in the hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
RamiprilCandesartan
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking Hopace H 5 Capsule with Candesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Hopace H 5 Capsule together with Candesartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.
RamiprilEprosartan
Severe
How does the drug interact with Hopace H 5 Capsule:
Coadministration of Hopace H 5 Capsule together with eprosartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Hopace H 5 Capsule together with Eprosartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.
RamiprilLeflunomide
Severe
How does the drug interact with Hopace H 5 Capsule:
Taking leflunomide with Hopace H 5 Capsule can increase the risk of liver problems.

How to manage the interaction:
Although taking Hopace H 5 Capsule with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.

  • Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.

  • Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Hopace H 5 Capsule Substitute

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Alcohol

Unsafe

Hopace H 5 Capsule may enhance the hypotensive (low blood pressure) effect if alcohol is taken along with. For better advice, you should consult your doctor about whether you can take Hopace H 5 Capsule with alcohol.

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Pregnancy

Unsafe

The use of Hopace H 5 Capsule or any ACE inhibitors (Ramipril) is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Hopace H 5 Capsule .

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Breast Feeding

Caution

Use of Hopace H 5 Capsule is not recommended during the breastfeeding stage.

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Driving

Unsafe

Drive with caution, Hopace H 5 Capsule may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking Hopace H 5 Capsule , so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Hopace H 5 Capsule to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Hopace H 5 Capsule should be given with precaution in hemodialysis condition.

bannner image

Children

Caution

Hopace H 5 Capsule is not recommended for children. The safety and effectiveness of Hopace H 5 Capsule have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Hopace H 5 Capsule or not.

FAQs

Hopace H 5 Capsule is used to treat Hypertension (High blood pressure).
Usually, Hopace H 5 Capsule is prescribed for a long-term treatment ranging from weeks to months or for life long also for treating lowering raised blood pressure, swelling due to fluid overload (oedema) and heart-related conditions. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor prescribes it.
Yes, Hopace H 5 Capsule can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Hopace H 5 Capsule . In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.
If you forget to take Hopace H 5 Capsule at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
Yes, in some cases, Hopace H 5 Capsule may affect your serum potassium level, so consult your doctor before using potassium supplements or its salt substitutes.
Hopace H 5 Capsule should not be used if you have a history of a serious allergic reaction, including swelling of the face/lips/tongue/throat (angioedema) and an inability to make urine. Besides this, if you are using alcohol or recreational drugs, do not do hazardous work like driving a motor vehicle or operating heavy machinery. Before going outdoor in the sun, try to wear sunscreen (SPF) and avoid sunlamps and tanning booths as prolonged intake of Hopace H 5 Capsule may cause your skin to be sensitive to the sunlight.
Yes, if you have diabetes, Hopace H 5 Capsule may change your blood sugar level, so check your blood sugar regularly as directed. Tell your doctor if you have high blood sugar (hyperglycemia) symptoms like increased thirst/urination or signs of low blood sugar (hypoglycemia) such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor might adjust your dose of Hopace H 5 Capsule .
Hopace H 5 Capsule contains Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes. 
The common side effects of Hopace H 5 Capsule include headaches, tiredness, slow heart rate, and nausea. Most of these side effects gradually resolve over time; however, if they persist, please inform your doctor.
No, you should not stop treatment with Hopace H 5 Capsule even if you feel an improvement in your symptoms because high blood pressure often has no symptoms and can shoot up at any time. Continue taking it for as long as it has been advised by your doctor.
Yes, you can take Hopace H 5 Capsule every day if advised by the doctor. Just make sure to follow your doctor’s instructions regarding how long to use it. Taking it for years on your own without your doctor’s approval could be fatal.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - HOP0004

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