Holymet-XL 25 Tablet belongs to a group of medicines called beta-blockers used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Hypertension or high blood pressure is a chronic condition in which the blood exerts an increased pressure against the arteries that may lead to various types of heart diseases. Besides this, Holymet-XL 25 Tablet may also help in relieving symptoms of migraine-related headaches and tremors (fits). 

Holymet-XL 25 Tablet contains 'Metoprolol succinate', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. 

Take Holymet-XL 25 Tablet as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Holymet-XL 25 Tablet may cause certain common side effects like dizziness, tiredness, diarrhea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have low blood pressure, asthma, overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking Holymet-XL 25 Tablet if you are pregnant or breastfeeding. Holymet-XL 25 Tablet is not recommended for use in children. Holymet-XL 25 Tablet may cause dizziness, so drive with caution. Avoid alcohol consumption while taking Holymet-XL 25 Tablet as it might increase the blood pressure-lowering effect of Holymet-XL 25 Tablet. Keep your doctor informed about your health condition and medications to rule out any interactions.

Holymet-XL 25 Tablet belongs to a group of medicines called beta-blockers used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it also helps in relieving symptoms of migraine-related headaches and tremors (fits).  Holymet-XL 25 Tablet helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. 

• Dizziness
• Tiredness
• Diarrhoea
• Stomach pain
• Nausea
• Headache

Do not take Holymet-XL 25 Tablet if you are allergic to metoprolol succinate or any other beta-blockers. Avoid taking Holymet-XL 25 Tablet if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or prinzmetal angina. Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents. Consult your doctor before taking Holymet-XL 25 Tablet if you are pregnant or breastfeeding. Holymet-XL 25 Tablet is not recommended for children as safety and efficacy have not been established. Holymet-XL 25 Tablet may cause dizziness, so drive with caution. Let your doctor know if you are taking other prescription/non-prescription medicines or herbal supplements.

Drug-Drug Interaction: Holymet-XL 25 Tablet may interact with antacid (cimetidine), blood pressure-lowering agents (hydralazine, clonidine, prazosin), anti-arrhythmic (amiodarone, propafenone), anaesthetics (cyclopropane), anxiolytics (temazepam, nitrazepam, diazepam), NSAID's (indomethacin, celecoxib), antibiotic (rifampicin), anti-fungal (terbinafine), corticosteroids (hydrocortisone, prednisolone), a local anaesthetic (lidocaine), anti-depressants, barbiturates, phenothiazines, and other beta-blockers.

Drug-Food Interaction: Alcohol might increase the blood pressure-lowering effect of Holymet-XL 25 Tablet. It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Holymet-XL 25 Tablet.

Drug-Disease Interaction: Holymet-XL 25 Tablet may have interaction with disease conditions such as heart conduction problems, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma (tumour in the adrenal gland), metabolic acidosis (excess acid in the body), low blood pressure, and prinzmetal angina.

• CIMETIDINE
• HYDRALAZINE
• CLONIDINE
• PRAZOSIN
• AMIODARONE
• PROPAFENONE
• CYCLOPROPANE
• TEMAZEPAM
• NITRAZEPAM
• DIAZEPAM
• INDOMETHACIN
• CELECOXIB
• RIFAMPICIN
• TERBINAFINE
• HYDROCORTISONE
• PREDNISOLONE
• LIDOCAINE

• Do regular physical activity or exercise.

• Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

• Limit intake of sodium chloride (table salt) in your daily diet.

• Quitting smoking is the best strategy to lower the risk of heart disease. 

• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

• Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

• Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
• If you due to have any surgery, inform the doctor that you are taking Holymet-XL 25 Tablet.

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.