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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Holoxan Uromitexan 200mg/1gm Injection is used in the treatment of different kinds of cancer, such as blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Sometimes, you may experience specific side effects such as nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Before receiving this medicine, you should inform your doctor if you are allergic to any of its ingredients or if you are pregnant or breastfeeding, and about all the medications you are taking and any pre-existing medical conditions to rule out the potential side effects.

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Manufacturer/Marketer :

Zydus Cadila

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Holoxan Uromitexan 200mg/1gm Injection

Holoxan Uromitexan 200mg/1gm Injection is used to treat different cancers such as Blood, breast, non-small cell, ovarian, testicular, and pancreatic cancer. Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. These cells can form tumours or spread to other body parts, interfering with normal function.

Holoxan Uromitexan 200mg/1gm Injection is a combination medication. It contains ifosfamide (antineoplastic agent) and mesna (cytoprotectants). Holoxan Uromitexan 200mg/1gm Injection works by damaging the genetic material (DNA and RNA) of cancer cells, stopping their growth and multiplication. 

Sometimes, you may experience specific side effects such as nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Most of these side effects will resolve gradually over time and do not require medical attention. However, consult the doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Holoxan Uromitexan 200mg/1gm Injection may cause dizziness. Therefore, avoid driving or operating heavy machinery unless you are fully alert. Holoxan Uromitexan 200mg/1gm Injection is safe for children if prescribed by the doctor. Holoxan Uromitexan 200mg/1gm Injection should not be given to children as its safety and efficacy have not been established. Consumption of alcohol is not recommended while receiving this Holoxan Uromitexan 200mg/1gm Injection as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, and seizures. Inform your doctor about your pre-existing medical conditions and if you are taking any other medications to prevent potential side effects.

Uses of Holoxan Uromitexan 200mg/1gm Injection

Holoxan Uromitexan 200mg/1gm Injection is used in the treatment of Blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer.

Directions for Use

Holoxan Uromitexan 200mg/1gm Injection will be administered by a healthcare professional through the Intravenous route. Do not self-administer.

Medicinal Benefits

Holoxan Uromitexan 200mg/1gm Injection belongs to the group of medicines called antineoplastic agents. Holoxan Uromitexan 200mg/1gm Injection is a combination of two drugs, Ifosfamide (antineoplastic agent) and mesna (cytoprotectants), used to treat different kinds of cancers such as blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Holoxan Uromitexan 200mg/1gm Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.

How Holoxan Uromitexan 200mg/1gm Injection Works

Holoxan Uromitexan 200mg/1gm Injection contains Ifosfamide (an antineoplastic agent) and mesna (cytoprotectant). Ifosfamide damages the genetic material (DNA and RNA) of cancer cells, stopping their growth and multiplication. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Holoxan Uromitexan 200mg/1gm Injection

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhoea
  • Dizziness
  • Loss of appetite
  • Headache
  • Hair loss
  • Pain or redness at the injection site
  • Fever
  • Sore throat
  • Cough

What if I have taken an overdose of Holoxan Uromitexan 200mg/1gm Injection

Since the doctor or nurse will administer the medication, the risk of overdose is minimal. However, in the case of any accidental overdose, it is essential to contact the doctor immediately for prompt care and ensure the patient is closely monitored.

Drug Warnings

Holoxan Uromitexan 200mg/1gm Injection should not be administered to individuals if they are allergic to it or its ingredients. Women of childbearing age should use effective birth control during treatment and for at least six months after the last dose to avoid pregnancy. Regular urine and blood tests, including CBC, are required to monitor blood cell counts while receiving Holoxan Uromitexan 200mg/1gm Injection. Holoxan Uromitexan 200mg/1gm Injection is not intended for use in conditions like haematuria due to thrombocytopenia or other underlying diseases. It may cause blurry vision and dizziness; therefore, avoid driving or operating heavy machinery while treating with Holoxan Uromitexan 200mg/1gm Injection. Inform your doctor if you have a history of kidney, heart, liver disease, cystitis, or CNS toxicity before starting therapy with Holoxan Uromitexan 200mg/1gm Injection. Avoid the consumption of alcohol as it may cause interactions and lead to unpleasant side effects. Holoxan Uromitexan 200mg/1gm Injection is unsafe during pregnancy and breastfeeding. Patients with infections should exercise caution, and chemotherapy may be temporarily stopped if fever or signs of infection occur. Holoxan Uromitexan 200mg/1gm Injection may cause bone marrow suppression, decreasing white blood cells and platelets, so regular monitoring is essential.

Diet & Lifestyle Advise

  • Eat protein-rich, low-fat foods like eggs, Greek yoghurt, seafood, lean meats, poultry, beans, soy products, and unsalted nuts.
  • Include vitamin A-rich foods like carrots, sweet potatoes, kale, spinach, and apricots.
  • Avoid intake of fatty, fried, spicy, and overly sweet foods to avoid nausea.
  • Practise good hygiene by staying away from crowded places, and avoiding raw and undercooked food to reduce the risk of infection.
  • Avoid refined sugars and carbohydrates, as tumours often use glucose for energy.
  • Avoid consumption of alcohol and quit smoking.
  • Empty your bladder frequently within 24 hours of chemotherapy; inform your doctor if you experience pain during urination.
  • Get at least 8 hours of sleep and rest regularly.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Holoxan Uromitexan 200mg/1gm Injection Substitute

Substitutes safety advice
  • Ifomid-M Injection 1's

    by AYUR

    396.90per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while treatment with Holoxan Uromitexan 200mg/1gm Injection as it may cause unpleasant side effects.

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Pregnancy

Unsafe

Holoxan Uromitexan 200mg/1gm Injection is not recommended to be used in pregnancy as it may cause serious side effects. Use effective birth control measures during treatment with Holoxan Uromitexan 200mg/1gm Injection and for 6 months after completing the treatment. Inform your doctor If you get pregnant while you are receiving Holoxan Uromitexan 200mg/1gm Injection.

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Breast Feeding

Unsafe

Holoxan Uromitexan 200mg/1gm Injection is excreted in breast milk. Ifosfamide has been demonstrated to produce significant adverse effects and tumours in animal tests. It is essential to consider the importance of the medicine to the mother before discontinuing nursing. Ifosfamide should not be taken by women who are breastfeeding.

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Driving

Caution

Some patients may experience blurred vision or dizziness after using this $ name. If you experience any of these symptoms during treatment, do not drive a vehicle or operate heavy machinery.

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Liver

Caution

There were no official investigations undertaken on patients with liver impairment. Holoxan Uromitexan 200mg/1gm Injection is metabolized extensively in the liver, producing both beneficial and harmful metabolites. It should be administered with caution to patients with poor liver function.

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Kidney

Caution

There were no official studies undertaken on people with kidney impairment. The kidneys eliminate Holoxan Uromitexan 200mg/1gm Injection and metabolites but may accumulate in plasma with impaired renal function. Patients with renal impairment should be continuously watched for toxicity, and dose reduction may be necessary.

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Children

Caution

Holoxan Uromitexan 200mg/1gm Injection is not recommended for use in children under 12 years of age as its safety and efficacy have not been established.

FAQs

Holoxan Uromitexan 200mg/1gm Injection belongs to the group of medications called antineoplastic agents. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer and pancreatic cancer.
Holoxan Uromitexan 200mg/1gm Injection is an antineoplastic agent. It works by damaging the DNA of cancer cells, preventing their growth and spread. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.
Holoxan Uromitexan 200mg/1gm Injection may cause diarrhoea as a common side effect. If you experience this symptom, drink plenty of fluids to stay hydrated, eat non-spicy food, get plenty of rest, and take probiotics. Do not take anti-diarrheal medicines on your own without a doctor’s advice.
The side effects of Holoxan Uromitexan 200mg/1gm Injection include nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Most of these side effects will resolve gradually over time and do not require medical attention. However, consult the doctor if you experience these side effects persistently.

Manufacturer/Marketer address

Office No. 5119, 5Th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072
Other Info - HO64214

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