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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST
Histolaf 10 mg Tablet is used in the treatment of peptic ulcers and gastroesophageal reflux disease (acid reflux). It contains Lafutidine, which reduces the amount of acid in the stomach and helps in relieving acid-related indigestion and heartburn. It may cause side effects such as drowsiness, extreme tiredness, headache, constipation, diarrhea, and muscle pain.
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Composition :

LAFUTIDINE-10MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Histolaf 10 mg Tablet

Histolaf 10 mg Tablet belongs to a class of medicines called ‘H2-receptor antagonists’. It is used in the treatment of peptic ulcers and gastroesophageal reflux disease (acid reflux). Peptic ulcers are sores that develop in the lining of the stomach, lower esophagus or small intestine. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the tube connecting your mouth and stomach (esophagus). This backwash (acid reflux) can irritate the lining of your esophagus.

Histolaf 10 mg Tablet contains ‘lafutidine’ which acts as an antacid. It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Histolaf 10 mg Tablet must be taken in the dose and duration advised by the doctor. Based on the severity of the medical condition, your doctor may prescribe Histolaf 10 mg Tablet to take once daily before bedtime or twice daily in the morning and before bedtime with or without food. Common side-effects of Histolaf 10 mg Tablet are fatigue, drowsiness, headache, increased liver enzymes, constipation, increased uric acid level in the blood, diarrhea, muscle pain, protein in the urine. These side effects resolve on their own, if it persists, stop the Histolaf 10 mg Tablet and contact your doctor immediately.

Do not take Histolaf 10 mg Tablet if you are allergic, other H2 receptor antagonists, or any other ingredients present in it. Before taking Histolaf 10 mg Tablet , inform your doctor if you are taking prescription or non-prescription medications, including antacids, nutritional supplements, or herbal products. Inform your doctor if you have any gastrointestinal problems, kidney diseases, and liver diseases. Inform your doctor if you are pregnant or planning to become a pregnant/breastfeeding woman.

Uses of Histolaf 10 mg Tablet

Treatment of Gastroesophageal reflux disease (acid reflux) and Peptic ulcer disease.

Medicinal Benefits

Histolaf 10 mg Tablet belongs to a group of medicines called ‘H2-receptor antagonists’, which acts as an antacid. It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn. It is used in the treatment of peptic ulcers and gastroesophageal reflux disease (acid reflux). It is also used in the treatment of Zollinger-Ellison syndrome (a condition in which the tumors formed in the pancreas, and duodenum increases stomach acids) and gastric mucosal lesions.

Side Effects of Histolaf 10 mg Tablet

  • Fatigue 
  • Drowsiness
  • Headache
  • Increased liver enzymes
  • Constipation 
  • Increased uric acid level in blood
  • Diarrhea
  • Muscle pain
  • Protein in urine

Directions for Use

Histolaf 10 mg Tablet must be taken in the dose and duration advised by the doctor. Do not crush or break or chew the Histolaf 10 mg Tablet .Swallow it with a glass full of water.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Histolaf 10 mg Tablet if you are allergic, other H2 receptor antagonists, or any other ingredients present in it. Before taking Histolaf 10 mg Tablet , inform your doctor if you are taking prescription or non-prescription medications, including antacids, any nutritional supplements, or herbal products. Inform your doctor if you have any gastrointestinal problems, kidney diseases, and liver diseases. Inform your doctor if you are pregnant or planning to become pregnant/breast-feeding women. Histolaf 10 mg Tablet should be used with caution in the elderly patients due to the increased risk of severe adverse effects. Histolaf 10 mg Tablet should be used with caution in patients on dialysis due to the increased risk of worsening of the patient's condition. Close monitoring of renal function is necessary for such patients during treatment with this medicine. Histolaf 10 mg Tablet may cause shock and anaphylactic reactions in some patients. Report any symptoms such as pale skin, dizziness, breathing difficulty, etc. to the doctor immediately.

Therapeutic Class

ANTACIDS

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Maintain a healthy weight. Lose excess weight if you are overweight or obese.  
  • Do not lie down immediately after eating.
  • Eat smaller meals in short intervals. 
  • Elevate the head of the bed while sleeping. 
  • Quit smoking.
  • Reduce caffeine and alcohol intake.
  • Reduce stress.
  • Do not take nonsteroidal anti-inflammatory drugs (NSAIDs) without the doctor's advice.
  • Avoid spicy foods and carbonated drinks.
  • Avoid eating citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.

Habit Forming

No

How Histolaf 10 mg Tablet Works

Histolaf 10 mg Tablet contains ‘lafutidine’ which acts as an antacid. It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

What if I have taken an overdose of Histolaf 10 mg Tablet

Do not take more than the prescribed dose of Histolaf 10 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

Histolaf 10 mg Tablet may interact with alcohol and increase the risk of side-effects.

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Pregnancy

Caution

Histolaf 10 mg Tablet is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

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Breast Feeding

Caution

Histolaf 10 mg Tablet medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

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Driving

Caution

Histolaf 10 mg Tablet may cause dizziness and headache. So, you should not drive or operate heavy machinery after taking Histolaf 10 mg Tablet .

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Liver

Caution

Histolaf 10 mg Tablet should be used with caution in patients with liver diseases. Consult your doctor before using Histolaf 10 mg Tablet , dose-adjustments may be done by your doctor.

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Kidney

Caution

Histolaf 10 mg Tablet should be used only when prescribed by a doctor. Dose adjustments may be necessary

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Children

Caution

Histolaf 10 mg Tablet is not recommended for use in children, because safety of the drug is not clearly established.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - HIS0099

Author Details

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FAQs

Histolaf 10 mg Tablet is used in the treatment of peptic ulcers and gastroesophageal reflux disease (acid reflux).
Histolaf 10 mg Tablet works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Do not take Histolaf 10 mg Tablet for the long term unless prescribed by a doctor. Prolonged use may cause unwanted side-effects. So, discuss with your doctor the benefits and risks associated with the drug before using it for the long-term.
Histolaf 10 mg Tablet cause common side effects like fatigue, drowsiness, headache, increased liver enzymes, constipation, increased uric acid level in blood, diarrhea, muscle pain, protein in urine.
Histolaf 10 mg Tablet should be taken at night time as acid reflux is usually worse at night time. Take the tablet at a fixed time every day for better results.
Histolaf 10 mg Tablet should not be stopped suddenly. Consult your doctor before stopping the Histolaf 10 mg Tablet .
Histolaf 10 mg Tablet can be taken with food or without food as recommended by the doctor.
Histolaf 10 mg Tablet starts working within one to three hours and lasts for about 10-12 hours. Keep taking Histolaf 10 mg Tablet for the prescribed duration for effective treatment.
Histolaf 10 mg Tablet and omeprazole are two different drugs that belong to different groups of medications. However, both are used to treat stomach acid-related conditions. Histolaf 10 mg Tablet belongs to H2 receptor antagonists (H2 blockers) whereas omeprazole is a proton-pump inhibitor.
No, do not drink alcohol while taking Histolaf 10 mg Tablet as it may increase dizziness, drowsiness, and sleepiness.
Histolaf 10 mg Tablet may cause serious side effects like skin rash, hives, hoarseness, breathing difficulties, itching, and difficulty swallowing. Consult the doctor immediately if you notice any of these symptoms.
Do not take Histolaf 10 mg Tablet if you are allergic to any of its components or other H2 receptor antagonists. Avoid taking painkillers unless advised by the doctor as it might cause stomach irritation. Eat smaller, frequent meals, and chew properly. Limit the intake of caffeine, tea, cocoa as they might irritate the stomach.

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