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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:20 PM IST

Histoglob Injection 1 ml is used to treat allergic reactions like allergic rhinitis (inflammation in the nose) and urticaria (the occurrence of swollen, pale red bumps or plaques on the skin). It is also used in treating eczema (a skin condition that causes patches of itchiness, inflammation, swelling, and cracked skin). It contains Human Normal Immunoglobulin, Histamine and Sodium Thiosulphate. It works by blocking the action of certain chemical messengers that are responsible for inflammation, congestion, itching and other allergic reactions.

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Manufacturer/Marketer

Bharat Serums and Vaccines Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Histoglob Injection 1 ml

Histoglob Injection 1 ml is used in the treatment of allergic reactions like allergic rhinitis (inflammation in the nose) and urticaria (the occurrence of swollen, pale red bumps or plaques on the skin). It is also used in treating eczema (a skin condition that causes patches of itchiness, inflammation, swelling, and cracked skin) and premenstrual syndrome (PMS).

Histoglob Injection 1 ml is a combination of three medicines: Human Normal Immunoglobulin, Histamine, and Sodium Thiosulphate. These medicines are used to treat allergic reactions like allergic rhinitis and urticaria. This medicine works by blocking the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions. 

Histoglob Injection 1 ml will be administered by a trained healthcare professional. Hence, do not self-administer. This medicine may cause certain side effects such as swelling or hardening at the injection site, headache, and flu-like illness (runny nose and sore throat). These side effects are usually mild and temporary. However, if any of the side effects persist or get worse, inform your doctor immediately.

Histoglob Injection 1 ml should be avoided if you are allergic to any of its components. Before receiving Histoglob Injection 1 ml, inform your doctor if you have had any vaccinations recently or have already had this product recently. Histoglob Injection 1 ml should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections). Histoglob Injection 1 ml is not recommended for use in pregnant women, during menstruation and during an acute allergic attack. Inform your doctor about all your medical conditions along with your medication history, including herbal and vitamin supplements.

Uses of Histoglob Injection 1 ml

Treatment of Allergic rhinitis, Urticaria, Eczema and Premenstrual syndrome (PMS)

Medicinal Benefits

Histoglob Injection 1 ml contains a combination of three medicines, Human Normal Immunoglobulin, Histamine and Sodium Thiosulphate, which are used in the treatment of allergic reactions like allergic rhinitis and urticaria. This medicine works by blocking the action of certain chemical messengers that are responsible for inflammation, congestion, itching and other allergic reactions. It is also used in the treatment of eczema, premenstrual syndrome, bronchitis, and migraine. Histoglob Injection 1 ml is also used as prophylaxis treatment in children (where there is a family history of allergy) who are about to undergo an adenoidectomy or tonsillectomy.

Directions for Use

Histoglob Injection 1 ml is intended for subcutaneous use only. A trained healthcare professional will administer it. So, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Histoglob Injection 1 ml

  • Injection site reactions
  • Headache
  • Swelling or hardening at the injection site
  • Fever

Drug Warnings

Histoglob Injection 1 ml should be avoided if you are allergic to any of its components. Before receiving Histoglob Injection 1 ml, inform your doctor if you have had any vaccinations recently or have already had this product recently. Histoglob Injection 1 ml should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections). This medicine is intended for subcutaneous administration (injection given in the fatty tissue, just under the skin) only. Histoglob Injection 1 ml is not recommended for use in pregnant women, during menstruation and during an acute allergic attack. Inform your doctor about all your medical conditions along with your medication history, including herbal and vitamin supplements. Histoglob Injection 1 ml should be used with caution in people with obesity or overweight, diabetes, high blood pressure (hypertension), hypovolemia (low blood volume), and blood clotting disorders, as there is a risk of developing a blood clot (very rare effect of Histoglob Injection 1 ml). Also, let your doctor know if you have any kidney problems.

Drug Interactions

Drug-Drug Interactions: Histoglob Injection 1 ml may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Histoglob Injection 1 ml should be used with caution in people with blood clotting disorders, kidney disease and immunoglobulin A (IgA) deficiency.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • MMR VACCINE
  • VARICELLA (LIVE ATTENUATED)

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet that includes grains,  fresh fruits, vegetables, lean meats, and dairy products. 
  • Stay active and do moderate exercises every day. Maintain a normal weight.
  • Get enough sleep, as sleep and immunity are closely related.
  • Limit intake of sugar-rich foods or drinks.
  • Staying hydrated is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate cough, runny nose and sneezing.
  • Manage stress levels. 
  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean.

Special Advise

  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.

  • Histoglob Injection 1 ml should not be given intravenously.

  • Do not take any vaccines (especially live vaccines) at least three months after taking Histoglob Injection 1 ml as this medicine may make the vaccine less effective.

Disease/Condition Glossary

Allergic rhinitis: When the immune system overreacts to allergens in the air, allergic rhinitis, a type of nasal inflammation, results. Runny or stuffy nose, sneezing, red, itchy, and watery eyes, as well as swelling around the eyes, are signs and symptoms of this condition. Dust mites, pollen, spores, animal skin, urine, and saliva are among the most common airborne allergens that cause rhinitis.

Urticaria: Hives, or urticaria, are sudden outbreaks of swollen, pale red bumps or plaques (wheals) on the skin that can occur as a result of an immune system reaction to certain allergens or for unknown causes. The skin's surface may develop welts that are itchy, raised, red, or skin-coloured.

Premenstrual syndrome (PMS): It is a condition in which a group of symptoms occurs between ovulation and menstruation. Symptoms of PMS include mood swings, fatigue, food cravings, breast tenderness, and irritability.

Eczema is a condition in which skin patches become inflamed, itchy, cracked, and rough. Symptoms include a rash on the arms and behind the knees. Eczema can be triggered by various factors, such as foods, drinks, skin products, soaps, chemicals, detergents, make-up products, chlorinated pools, and stress.

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Alcohol

Safe

Histoglob Injection 1 ml may not interact with alcohol. However, limit or avoid the consumption of alcohol to avoid possible side effects.

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Pregnancy

Unsafe

Histoglob Injection 1 ml is not recommended for use in pregnant women. Hence, inform your doctor if you are pregnant or planning to become pregnant before receiving Histoglob Injection 1 ml. Your doctor may suggest an alternative medicine based on your health condition.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding before receiving Histoglob Injection 1 ml. Your doctor will assess the benefits and the risks before prescribing.

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Driving

Safe

Histoglob Injection 1 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases. Your doctor will weigh the benefits and potential risks before prescribing Histoglob Injection 1 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Histoglob Injection 1 ml.

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Children

Safe if prescribed

Histoglob Injection 1 ml can be safely used in children when prescribed by a paediatrician.

Country of origin

INDIA

Manufacturer/Marketer address

17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Other Info - HIS0010

FAQs

Histoglob Injection 1 ml is used to treat Allergic rhinitis, Urticaria, Eczema and Premenstrual syndrome (PMS).
Histoglob Injection 1 ml contains a combination of three medicines, Human Normal Immunoglobulin, Histamine and Sodium Thiosulphate, which are used in the treatment of allergic reactions like allergic rhinitis and urticaria. This medicine works by blocking the action of certain chemical messengers that are responsible for inflammation, congestion, itching and other allergic reactions. It is also used in the treatment of eczema, premenstrual syndrome, bronchitis, and migraine.
Histoglob Injection 1 ml may alter some blood test results for a certain time, so inform your doctor that you have received Histoglob Injection 1 ml before undergoing blood tests. Taking any vaccines (especially live vaccines) at least three months after the administration of Histoglob Injection 1 ml is not recommended as this medicine may make the vaccines less effective.
Histoglob Injection 1 ml is generally used in children. However, it should be used only if recommended by the paediatrician.
Histoglob Injection 1 ml will be administered by the doctor or nurse through a subcutaneous route (injection given in the fatty tissue, just under the skin). Do not self-administer.
Inform the doctor about your complete medical history, including any medications, herbal supplements, and vitamins you are taking or if you have recently received any vaccinations. Let the doctor know if you are breastfeeding, as they will assess the risks and benefits before administering Histoglob Injection 1 ml. This medication is not recommended for use during pregnancy, so inform your doctor if you are pregnant or planning to become pregnant. Your doctor may suggest an alternative treatment based on your health condition.
Allergic rhinitis is an allergic reaction that affects the nasal passages, leading to symptoms such as sneezing, a runny nose, and congestion. Chronic urticaria, or hives, involves the recurring appearance of raised, itchy welts on the skin due to an allergic response or other triggers. The main difference is that allergic rhinitis affects the nose, whereas chronic urticaria affects the skin.
Histoglob Injection 1 ml should not be administered if you are allergic to any of its ingredients. Do not receive any vaccines, especially live vaccines, for at least three months after taking Histoglob Injection 1 ml, as this medication may reduce the effectiveness of the vaccine.
Histoglob Injection 1 ml is not recommended for use during pregnancy. Therefore, inform your doctor if you are pregnant or planning to become pregnant before receiving this injection. Your doctor may recommend an alternative treatment.
You should inform the doctor if you are breastfeeding before receiving Histoglob Injection 1 ml. The doctor will evaluate the potential benefits and risks before administering Histoglob Injection 1 ml.
It is unlikely that Histoglob Injection 1 ml interacts with alcohol. However, it is recommended to limit or avoid alcohol consumption to reduce the risk of potential side effects.
The side effects of Histoglob Injection 1 ml include headache, swelling or hardening at the injection site, and flu-like symptoms (such as runny nose and sore throat). These side effects are typically mild and temporary. However, if any of these side effects persist or worsen, consult the doctor.

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