Histacalamine Lotion 125 ml belongs to the class of medication called 'astringent' or anti-allergic, primarily used to treat skin infections (cuts, wounds, small burns) and allergies. Skin infection may occur when the skin is broken, cut or wounded. An allergy occurs when foreign elements known as allergens attack and invade our body, thereby causing histamine release (a chemical messenger) that causes swelling, inflammation, redness, itchiness, watery nose, throat, and eyes. 

Histacalamine Lotion 125 ml contains Chlorpheniramine (anti-histamine) and Calamine (astringent). Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It directly acts on the brain and relieves allergy symptoms by preventing histamine release. Calamine is an astringent with antiseptic and soothing agent properties. So, it helps to heal wounds, cuts and burns. Collectively, both act as soothing lotions to treat skin infections.

Take Histacalamine Lotion 125 ml as prescribed by your doctor. You are advised to take Histacalamine Lotion 125 ml for as long as your doctor has prescribed it based on your medical condition. Some people may experience application site irritation, skin irritation, and a burning sensation. Most of these side effects of Histacalamine Lotion 125 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Please inform your doctor if you are allergic to Histacalamine Lotion 125 ml or other medicines. Please consult a doctor before taking Histacalamine Lotion 125 ml if you are pregnant or breastfeeding. Avoid using Histacalamine Lotion 125 ml if you have taken drugs such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Cover the open wounds with a sterile dressing or bandage after applying the Histacalamine Lotion 125 ml. Wash your hands before and after using Histacalamine Lotion 125 ml.

Histacalamine Lotion 125 ml contains Chlorpheniramine (anti-allergic drug) and Calamine (astringent). It temporarily relieves itching; pain is caused due to minor wounds (burns, cuts and scrapes). It also treats eczema, rashes, insect bites, and sunburn. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Calamine is an astringent with antiseptic and soothing agent properties. So, it helps to heal wounds, cuts and burns. Collectively, both act as soothing lotions to treat skin infections.

• Burning sensation
• Application site reaction
• Skin irritation

Please consult a doctor before taking Histacalamine Lotion 125 ml if you are pregnant or breastfeeding. Avoid using Histacalamine Lotion 125 ml if you have taken antidepressants medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection (for diagnosis) in the past 14 days as Histacalamine Lotion 125 ml has chlorpheniramine. In children under two years of age, Histacalamine Lotion 125 ml should not be used for skin irritation. Do not take $nma if you have haemorrhoids or other genital/anal conditions in children less than the age of 12 years. Drink plenty of fluids while taking Histacalamine Lotion 125 ml to protect yourself from being dehydrated or overheated during exercise and in hot weather, as Histacalamine Lotion 125 ml decreases sweating and increases heatstroke risk.

Drug-Drug Interactions: Histacalamine Lotion 125 ml may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine), anticonvulsants (phenytoin) and antianxiety drugs (alprazolam).

Drug-Food Interactions:  No interactions found.

Drug-Disease Interactions: If you have liver or kidney problems, haemorrhoids, or genital or anal problems, inform your doctor before taking the Histacalamine Lotion 125 ml.

• DIPHENHYDRAMINE
• CETIRIZINE
• DULOXETINE
• PHENYTOIN
• ALPRAZOLAM

• Wash your hands with soap and water regularly to prevent the spread of germs.
• Eat plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
• Drink plenty of fluids to avoid dehydration.
• Gargle with salt water for relief from sore throat.
• Avoid consumption of alcohol with Histacalamine Lotion 125 ml as it may cause tiredness, drowsiness or lack of concentration.
•  Do not scratch or pick your skin to avoid infecting the affected area.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Do not walk barefoot at places like gym showers to prevent bacterial infections.

• If you have used any MAO inhibitors or anti-depressant pills like Isocarboxazid, Phenelzine, Selegiline, or Tranylcypromine in the last 14 days, do not take Histacalamine Lotion 125 ml.

Allergies: Allergies occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamine' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever etc.

Skin infection: Skin infection can occur when the skin is broken, cut or wounded. This skin infection allows pathogenic microorganisms to enter and invade the tissues surrounding the wound.