Hicune-200 Tablet belongs to the class of 'anti-inflammatory drugs.' It has various medical uses, including treatment for type 2 diabetes mellitus, acute or chronic rheumatoid arthritis, dyslipidaemia (abnormally elevated cholesterol levels), systemic and discoid lupus erythematosus (autoimmune disease), polymorphous light eruption (a rash caused by sun exposure), and malaria. 

Hicune-200 Tablet contains Hydroxychloroquine, an anti-inflammatory drug. For diabetes, it works by improving insulin sensitivity and increasing insulin secretion. In rheumatoid arthritis, Hydroxychloroquine acts as a mild immunosuppressant and disease-modifying anti-rheumatic agent and inhibits the production of rheumatoid factor. It also decreases the severity of skin lesions in systemic and discoid lupus erythematosus. In malaria, it works by increasing the concentration of a toxic compound in the parasite that leads to its death.

Take this medicine as prescribed by a doctor. Hicune-200 Tablet may cause common side effects like blurred vision, abdominal pain, nausea, vomiting, loss of appetite, diarrhoea, headache, mood changes, skin rashes, itching, sensitivity to light, and pigmentation disorders. These side effects are not familiar to everyone and may vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Before taking Hicune-200 Tablet , please inform your doctor if you are allergic to medicines, liver/kidney/heart diseases, gastrointestinal problems, blood disorders, and brain-related problems. Pregnant and breastfeeding women should consult their doctor before starting Hicune-200 Tablet . Hicune-200 Tablet may cause blurred vision; hence do not drive or operate machinery until you feel better. The safety and efficacy of Hicune-200 Tablet have not been established in children; please seek medical advice for more information.

Hydroxychloroquine has diversified medical uses and works by reducing inflammation in people with autoimmune diseases. It helps treat type 2 diabetes mellitus and autoimmune conditions like rheumatoid arthritis, systemic lupus erythematosus, and malaria. For diabetes, it works by improving insulin sensitivity and increasing insulin secretion. In rheumatoid arthritis, Hydroxychloroquine acts as a mild immunosuppressant and disease-modifying anti-rheumatic agent and inhibits the production of rheumatoid factor. In malaria, it works by increasing the concentration of a toxic compound in the parasite that leads to its death. Hydroxychloroquine is an anti-thrombotic and anti-platelet agent that helps reduce abnormally elevated cholesterol levels. It also decreases the severity of skin lesions in systemic and discoid lupus erythematosus.

• Blurred vision
• Abdominal pain
• Nausea
• Vomiting
• Loss of appetite
• Diarrhoea
• Headache
• Mood changes
• Skin rashes
• Itching
• Sensitivity to light
• Pigmentation disorders

Before using Hicune-200 Tablet , inform your doctor if you have recently used any prescription and non-prescription medications. Keep your doctor informed of your medical history before starting Hicune-200 Tablet . Please seek medical advice if you are pregnant or breastfeeding before taking Hicune-200 Tablet . This medicine may cause blurred vision; hence drive or operate machinery only when you are alert and have clear vision. Avoid alcohol consumption while being treated with Hicune-200 Tablet . Safety and efficacy of Hicune-200 Tablet have not been established in children.

Drug-Drug Interaction: Hicune-200 Tablet may interact with anti-cancer drugs (tamoxifen), heart-related medicines (digoxin, amiodarone), anti-diabetic drugs (insulin), anti-malarial drugs (halofantrine, mefloquine), antibiotics (moxifloxacin, azithromycin, penicillamine), immunosuppressants (ciclosporin), heartburn medicines (cimetidine), antipsychotics (amisulpride, quetiapine), fits medicines, and anticoagulants.

Drug-Food Interaction: Avoid alcohol consumption while using Hicune-200 Tablet .

Drug-Disease Interaction: Before using Hicune-200 Tablet , let your doctor know if you have any medical history of liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency (a genetic enzyme deficiency), high blood pressure, serious stomach or gut problems, nervous system problems, psoriasis, porphyria (a blood disorder), history of heart attack (myocardial infarction), electrolyte imbalance, fits, damaged retina or vision problems, and allergic reactions to medicines.

• TAMOXIFEN
• DIGOXIN
• AMIODARONE
• HALOFANTRINE
• MEFLOQUINE
• MOXIFLOXACIN
• AZITHROMYCIN
• PENICILLAMINE
• CICLOSPORIN
• CIMETIDINE
• AMISULPRIDE
• QUETIAPINE
• INSULIN HUMAN

• Maintain a fibre-rich diet and include fruits, vegetables and whole grains to maintain your blood glucose levels.
• Eat at regular intervals.
• Keep a check on your weight and exercise regularly to keep your heart healthy.
• Notice and manage the early symptoms of high/low blood sugar levels.
• During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.
• Include high-fibre foods like green leafy vegetables and fruits to aid digestion.
• Avoid or limit the intake of alcohol and caffeine.

• Let your doctor/laboratory staff know that you are taking Hicune-200 Tablet if you undergo medical tests.
• While being treated with Hicune-200 Tablet , your doctor may suggest ECG (electrocardiogram) to monitor your heart health.
• Your doctor may also suggest tests for blood cell counts (during prolonged therapy) and liver and kidney function tests.

Diabetes mellitus: It is also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance), or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people above 40 years but can also occur in childhood based on the risk factors. 

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Symptoms include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools.

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.