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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Guficol 2miu Injection is used to treat bacterial infections. It contains Colistimethate which works by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as stomach upset, itching, rash, and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Gufic Criti Care

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Guficol 2miu Injection

Guficol 2miu Injection belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Guficol 2miu Injection does not work against infections caused by a virus.

Guficol 2miu Injection contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take Guficol 2miu Injection as prescribed by your doctor. You are advised to take Guficol 2miu Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of Guficol 2miu Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Guficol 2miu Injection or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking Guficol 2miu Injection. If you are pregnant or breastfeeding, please inform your doctor before taking Guficol 2miu Injection. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as Guficol 2miu Injection may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking Guficol 2miu Injection so that the dose may be reduced accordingly.

Uses of Guficol 2miu Injection

Treatment of Several bacterial infections

Directions for Use

Guficol 2miu Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Guficol 2miu Injection contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. Guficol 2miu Injection binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. Guficol 2miu Injection is used when other antibiotics are not suitable.

How Guficol 2miu Injection Works

Guficol 2miu Injection contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Guficol 2miu Injection

  • Dizziness
  • Stomach upset
  • Tingling
  • Difficulty in breathing

What if I have taken an overdose of Guficol 2miu Injection

Use Guficol 2miu Injection only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, confusion, loss of balance/coordination, rapid eye movement, severe numbness/tingling, weak/shallow breathing, problems with speech, and loss of consciousness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Guficol 2miu Injection or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking Guficol 2miu Injection. If you are pregnant or breastfeeding, please inform your doctor before taking Guficol 2miu Injection. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as Guficol 2miu Injection may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking Guficol 2miu Injection so that the dose may be reduced accordingly. Inform your anesthetist that you are taking Guficol 2miu Injection as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of Guficol 2miu Injection as prescribed by your doctor for effective results.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
ColistinGentamicin
Severe

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Guficol 2miu Injection:
Coadministration of Guficol 2miu Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Guficol 2miu Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
ColistinGentamicin
Severe
How does the drug interact with Guficol 2miu Injection:
Co-administration of Guficol 2miu Injection with Gentamicin can increase the levels and risk of Guficol 2miu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Gentamicin, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinNeomycin
Severe
How does the drug interact with Guficol 2miu Injection:
Combining Guficol 2miu Injection with Neomycin can increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Neomycin, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinAtracurium
Severe
How does the drug interact with Guficol 2miu Injection:
Coadministration of Atracurium with Guficol 2miu Injection can increase the risk of Atracurium side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Atracurium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, slurred speech, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinRocuronium bromide
Severe
How does the drug interact with Guficol 2miu Injection:
Coadministration of Rocuronium bromide with Guficol 2miu Injection may increase the side effects of Rocuronium bromide.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Rocuronium bromide, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinTenofovir alafenamide
Severe
How does the drug interact with Guficol 2miu Injection:
Combining Guficol 2miu Injection with Tenofovir alafenamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Tenofovir alafenamide, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
ColistinStreptomycin
Severe
How does the drug interact with Guficol 2miu Injection:
Coadministration of Streptomycin with Guficol 2miu Injection may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Streptomycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, muscle pain, dizziness, or palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ColistinEverolimus
Severe
How does the drug interact with Guficol 2miu Injection:
Coadministration of Guficol 2miu Injection with Everolimus can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Everolimus, it can be taken if prescribed by a doctor. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, or weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
ColistinTobramycin
Severe
How does the drug interact with Guficol 2miu Injection:
Coadministration of Tobramycin with Guficol 2miu Injection can increase the blood levels and risk of Guficol 2miu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Tobramycin, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
ColistinKanamycin
Severe
How does the drug interact with Guficol 2miu Injection:
Coadministration of Guficol 2miu Injection with Kanamycin can increase the level and risk of Guficol 2miu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 2miu Injection and Kanamycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, swelling, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Guficol 2miu Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Guficol 2miu Injection.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Guficol 2miu Injection Substitute

Substitutes safety advice
  • Promistin Ds 2million Iu Injection

    by AYUR

    2879.10per tablet
  • Icl 2Million IU Injection 1's

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    2377.80per tablet
  • Guficol Plus 2Miu Injection

    by AYUR

    2301.74per tablet
  • Zolineg 2Miu Inj

    by AYUR

    1653.30per tablet
  • Unilistin Forte 2 Million Iu

    by AYUR

    1668.60per tablet
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Alcohol

Caution

Interaction of Guficol 2miu Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Guficol 2miu Injection.

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Pregnancy

Caution

Guficol 2miu Injection is a category C pregnancy drug and is given to pregnant women only if it is essential. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Guficol 2miu Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Guficol 2miu Injection may cause confusion, vision problems or dizziness. Therefore, avoid driving if you experience any of these symptoms after taking Guficol 2miu Injection.

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Liver

Caution

Take Guficol 2miu Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Guficol 2miu Injection with caution, especially if you have a history of Kidney diseases/conditions as Guficol 2miu Injection may affect kidney function. The dose may be adjusted by your doctor as required.

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Children

Caution

Guficol 2miu Injection should be used with caution in children and in doses as prescribed by a doctor. Special care should be taken in new-born and premature babies as kidneys are not developed fully.

FAQs

Guficol 2miu Injection is used to treat bacterial infections.
Guficol 2miu Injection contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria.
You are not recommended to take Guficol 2miu Injection with gentamicin as co-administration of these two medicines may increase the risk of severe adverse effects such as kidney problems, hearing loss or respiratory depression especially in elderly people and in those who have preexisting kidney disease or who are dehydrated. However, please consult your doctor before taking Guficol 2miu Injection with other medicines.
Guficol 2miu Injection may cause dizziness as a common side effect. Avoid driving if you feel dizzy after taking Guficol 2miu Injection. However, if the condition persists or worsens, please consult a doctor.
Guficol 2miu Injection should be used with caution in patients receiving dialysis (the process of filtration and purification of blood using a machine). Therefore, if you are receiving dialysis, please inform your doctor before taking Guficol 2miu Injection so that the dose may be adjusted accordingly.
You are recommended to take Guficol 2miu Injection with extreme caution if you have kidney disease as it may worsen the condition. Regular monitoring of kidney functioning is recommended while taking Guficol 2miu Injection. Therefore, inform your doctor if you have any kidney problems before taking Guficol 2miu Injection.
Before taking Guficol 2miu Injection, inform your doctor if you have a history of kidney problems, myasthenia gravis (a condition that causes muscle weakness), porphyria (a blood disorder), or asthma. These conditions may affect your treatment or require special monitoring.
Guficol 2miu Injection is given by a healthcare professional as an infusion over 30–60 minutes or as a rapid injection within 5 minutes into a vein. Do not self-administer.
Do not use Guficol 2miu Injection if you are allergic to its active substances or any other polymyxins (group of antibiotics to treat bacterial infection). If you are unsure, consult your doctor before receiving Guficol 2miu Injection.
Guficol 2miu Injection is prescribed during pregnancy only if your doctor thinks that the benefits are greater than the potential risks. The safety of Guficol 2miu Injection during pregnancy has not been fully established. Therefore, consult your doctor before taking Guficol 2miu Injection if you are pregnant.
Guficol 2miu Injection is safe when used as per the dose and duration advised by a doctor.
Guficol 2miu Injection causes side effects such as dizziness, stomach upset, tingling, and difficulty in breathing. However, these do not require any medical treatment and gradually reduce over time. Contact a doctor if these side effects persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Other Info - GUF0010

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